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    trpc4apb transient receptor potential cation channel, subfamily C, member 4 associated protein b [ Danio rerio (zebrafish) ]

    Gene ID: 58089, updated on 2-Nov-2024

    Summary

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    Official Symbol
    trpc4apbprovided by ZNC
    Official Full Name
    transient receptor potential cation channel, subfamily C, member 4 associated protein bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-000330-2
    See related
    Ensembl:ENSDARG00000020647 AllianceGenome:ZFIN:ZDB-GENE-000330-2
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tap1b; fa04g10; wu:fa04g10
    Summary
    Predicted to act upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex. Orthologous to human TRPC4AP (transient receptor potential cation channel subfamily C member 4 associated protein). [provided by Alliance of Genome Resources, Nov 2024]
    Annotation information
    Annotation category: suggests misassembly
    Orthologs
    all
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    Genomic context

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    See trpc4apb in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (18759535..18777950, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (18833195..18851608, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene zgc:103759 Neighboring gene myosin, heavy chain 7B, cardiac muscle, beta b Neighboring gene epithelial membrane protein 3b (MAM blood group) Neighboring gene NSFL1 (p97) cofactor (p47)

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution and Distribution of Teleost myomiRNAs: Functionally Diversified myomiRs in Teleosts. Siddique BS, et al. Mar Biotechnol (NY), 2016 Jun. PMID 27262998
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Cul4A-RING E3 ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transient receptor potential cation channel, subfamily C, member 4 associated protein b
    Names
    trp4-associated protein 1b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310093.1 → NP_001297022.1  transient receptor potential cation channel, subfamily C, member 4 associated protein b

      Status: VALIDATED

      Source sequence(s)
      BC162514
      UniProtKB/TrEMBL
      A0A8M1P2D2
      Related
      ENSDARP00000133409.1, ENSDART00000169180.2
      Conserved Domains (1) summary
      pfam12463
      Location:382 → 689
      DUF3689; Protein of unknown function (DUF3689)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      18759535..18777950 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017353602.3 → XP_017209091.1  transient receptor potential cation channel, subfamily C, member 4 associated protein b isoform X1

      UniProtKB/TrEMBL
      A0A8M6Z4G5

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_131568.1: Suppressed sequence

      Description
      NM_131568.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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