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    heatr5a HEAT repeat containing 5a [ Danio rerio (zebrafish) ]

    Gene ID: 368728, updated on 2-Nov-2024

    Summary

    Official Symbol
    heatr5aprovided by ZNC
    Official Full Name
    HEAT repeat containing 5aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030616-152
    See related
    Ensembl:ENSDARG00000023999 AllianceGenome:ZFIN:ZDB-GENE-030616-152
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    CG2747; zgc:63665; si:dz142b24.3; si:busm1-142b24.3
    Summary
    Predicted to be involved in endocytosis; protein localization; and retrograde transport, endosome to Golgi. Predicted to be active in endocytic vesicle. Orthologous to human HEATR5A (HEAT repeat containing 5A). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See heatr5a in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (28624374..28669916)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (28607392..28652953)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene im:7136021 Neighboring gene MIS18 binding protein 1 Neighboring gene HECT domain containing 1 Neighboring gene adaptor related protein complex 4 subunit sigma 1 Neighboring gene striatin, calmodulin binding protein 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • KIAA1316, MGC63665

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein localization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in retrograde transport, endosome to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in endocytic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    HEAT repeat-containing protein 5A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200478.2NP_956772.2  HEAT repeat-containing protein 5A

      See identical proteins and their annotated locations for NP_956772.2

      Status: PROVISIONAL

      Source sequence(s)
      AL593845
      UniProtKB/Swiss-Prot
      Q7SXY8, Q8JFV4
      Related
      ENSDARP00000030254.6, ENSDART00000032975.8
      Conserved Domains (1) summary
      sd00044
      Location:97121
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      28624374..28669916
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009293121.2XP_009291396.1  HEAT repeat-containing protein 5A isoform X1

      See identical proteins and their annotated locations for XP_009291396.1

      UniProtKB/TrEMBL
      A0A8M3AJX9, E7F1I7
      Related
      ENSDARP00000107674.1, ENSDART00000122260.4
      Conserved Domains (1) summary
      sd00044
      Location:97121
      HEAT; HEAT repeat [structural motif]
    2. XM_009293123.2XP_009291398.1  HEAT repeat-containing protein 5A isoform X2

      UniProtKB/TrEMBL
      A0A2R8S021, A0A8M3ARG8
      Conserved Domains (1) summary
      sd00044
      Location:97121
      HEAT; HEAT repeat [structural motif]
    3. XM_009293122.2XP_009291397.1  HEAT repeat-containing protein 5A isoform X1

      See identical proteins and their annotated locations for XP_009291397.1

      UniProtKB/TrEMBL
      A0A8M3AJX9, E7F1I7
      Conserved Domains (1) summary
      sd00044
      Location:97121
      HEAT; HEAT repeat [structural motif]

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394995.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      524116..564576
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)