paxbp1 PAX3 and PAX7 binding protein 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: paxbp1provided by ZNC
Official Full Name: PAX3 and PAX7 binding protein 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-070112-2352
See related: Ensembl:ENSDARG00000062361 AllianceGenome:ZFIN:ZDB-GENE-070112-2352
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:158234
Summary: Predicted to enable DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within mRNA splicing, via spliceosome. Predicted to be active in nucleus. Orthologous to human PAXBP1 (PAX3 and PAX7 binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 10

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	10	NC_007121.7 (24421976..24442551)
105	previous assembly	GRCz10 (GCF_000002035.5)	10	NC_007121.6 (24452507..24473099)

Chromosome 10 - NC_007121.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: PAX3- and PAX7-binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080183.2 → NP_001073652.2 PAX3- and PAX7-binding protein 1

Status: VALIDATED

Source sequence(s)

AL929315

UniProtKB/TrEMBL

A0A8M1NBH2, E9QDJ4

Related

ENSDARP00000114980.1, ENSDART00000139850.3

Conserved Domains (2) summary

pfam07842
Location:570 → 783

GCFC; GC-rich sequence DNA-binding factor-like protein

pfam15458
Location:146 → 402

NTR2; Nineteen complex-related protein 2