tspan36 tetraspanin 36 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tspan36provided by ZNC
Official Full Name: tetraspanin 36provided by ZNC
Primary source: ZFIN:ZDB-GENE-040718-248
See related: Ensembl:ENSDARG00000024540 AllianceGenome:ZFIN:ZDB-GENE-040718-248
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: sb:cb666; zgc:100919
Summary: Acts upstream of or within pigmentation. Predicted to be located in Golgi membrane and endoplasmic reticulum membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including eye; gonad; heart; optic vesicle; and pigment cell. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 8

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (29726620..29734948)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (29717388..29725716)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Positional cloning and rescue identified dali as tetraspanin 3c (tspan3c), encoding a transmembrane scaffolding protein expressed by melanophores and xanthophores.
Title: Tetraspanin 3c requirement for pigment cell interactions and boundary formation in zebrafish adult pigment stripes.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within pigmentation	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: tetraspanin 36

Names: dali; tspan3c; vertebrate transmembrane 4 superfamily-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001002748.2 → NP_001002748.1 tetraspanin 36

See identical proteins and their annotated locations for NP_001002748.1

Status: VALIDATED

Source sequence(s)

AL928845, CT956087

UniProtKB/Swiss-Prot

Q6DGE3, Q6NWG0

Related

ENSDARP00000032359.6, ENSDART00000032498.7

Conserved Domains (1) summary

cd03163
Location:103 → 206

TM4SF8_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF8_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...