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    stap2a signal transducing adaptor family member 2a [ Danio rerio (zebrafish) ]

    Gene ID: 327172, updated on 2-Nov-2024

    Summary

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    Official Symbol
    stap2aprovided by ZNC
    Official Full Name
    signal transducing adaptor family member 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5383
    See related
    Ensembl:ENSDARG00000092810 AllianceGenome:ZFIN:ZDB-GENE-030131-5383
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb901; stap2; zgc:63913; wu:fd15d07
    Summary
    Predicted to enable signaling adaptor activity. Is expressed in nervous system; neural tube; and trigeminal placode. Orthologous to human STAP2 (signal transducing adaptor family member 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See stap2a in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (49522178..49569304)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (49787948..49835074)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene RAR-related orphan receptor C b Neighboring gene SH3-domain GRB2-like 1a Neighboring gene si:ch211-209f23.3 Neighboring gene semaphorin 4e Neighboring gene si:ch211-209f23.6 Neighboring gene cactin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Functional characterization of stap2b in zebrafish vascular development. Wang YS, et al. FASEB J, 2023 Jul. PMID 37342918
    2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables signaling adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    signal-transducing adaptor protein 2a
    Names
    signal-transducing adaptor protein-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198808.1 → NP_942103.1  signal-transducing adaptor protein 2a

      See identical proteins and their annotated locations for NP_942103.1

      Status: PROVISIONAL

      Source sequence(s)
      BC054569
      UniProtKB/TrEMBL
      F6NR58, Q1MT70, Q7T2F4
      Related
      ENSDARP00000056253.4, ENSDART00000056254.5
      Conserved Domains (2) summary
      cd09939
      Location:167 → 261
      SH2_STAP_family; Src homology 2 domain found in Signal-transducing adaptor protein (STAP) family
      cd13268
      Location:9 → 135
      PH_Brdg1; BCR downstream signaling 1 Pleckstrin homology (PH) domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      49522178..49569304
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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