npr1b natriuretic peptide receptor 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: npr1bprovided by ZNC
Official Full Name: natriuretic peptide receptor 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-100805-4
See related: Ensembl:ENSDARG00000018750 AllianceGenome:ZFIN:ZDB-GENE-100805-4
Gene type: protein coding
RefSeq status: MODEL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable guanylate cyclase activity and peptide receptor activity. Acts upstream of or within olfactory bulb axon guidance. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including eye; fin; integument; muscle; and renal system. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human NPR1 (natriuretic peptide receptor 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (28903743..28991376)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (28969131..29056750)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables guanylate cyclase activity	IEA Inferred from Electronic Annotation more info
enables lyase activity	IEA Inferred from Electronic Annotation more info
enables phosphorus-oxygen lyase activity	IEA Inferred from Electronic Annotation more info
enables protein kinase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cGMP biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cyclic nucleotide biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within intracellular signal transduction	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within olfactory bulb axon guidance	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within protein phosphorylation	IEA Inferred from Electronic Annotation more info