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    taf2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor [ Danio rerio (zebrafish) ]

    Gene ID: 324486, updated on 2-Nov-2024

    Summary

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    Official Symbol
    taf2provided by ZNC
    Official Full Name
    TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3207
    See related
    Ensembl:ENSDARG00000102307 AllianceGenome:ZFIN:ZDB-GENE-030131-3207
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc30f02; fc56a05; TAFII150; TAFII-150; wu:fc30f02; wu:fc56a05
    Summary
    Predicted to enable chromatin binding activity and transcription cis-regulatory region binding activity. Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in transcription initiation at RNA polymerase II promoter. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 40. Orthologous to human TAF2 (TATA-box binding protein associated factor 2). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See taf2 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (9580689..9606284)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (9689787..9715382)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 2 Neighboring gene mal, T cell differentiation protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Identification of 315 genes essential for early zebrafish development. Amsterdam A, et al. Proc Natl Acad Sci U S A, 2004 Aug 31. PMID 15256591, Free PMC Article
    2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC123088

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    contributes_to RNA polymerase II general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription cis-regulatory region binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in transcription initiation at RNA polymerase II promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription factor TFIID complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription factor TFIID complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transcription initiation factor TFIID subunit 2
    Names
    TAF(II)150
    TATA box binding protein (TBP)-associated factor 150kDa
    TBP-associated factor 150 kDa
    transcription initiation factor TFIID 150 kDa subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003835.2 → NP_001003835.2  transcription initiation factor TFIID subunit 2

      See identical proteins and their annotated locations for NP_001003835.2

      Status: VALIDATED

      Source sequence(s)
      CR854958
      UniProtKB/Swiss-Prot
      Q32PW3, Q5BJ13, Q6DGD5, Q6DRH8
      Related
      ENSDARP00000139157.1, ENSDART00000165565.2
      Conserved Domains (2) summary
      cd09839
      Location:16 → 530
      M1_TAF2; TATA binding protein (TBP) associated factor 2
      pfam13646
      Location:641 → 696
      HEAT_2; HEAT repeats

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      9580689..9606284
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021466622.2 → XP_021322297.1  transcription initiation factor TFIID subunit 2 isoform X1

      UniProtKB/TrEMBL
      A0A8M9NZ39
      Conserved Domains (1) summary
      cd09839
      Location:16 → 530
      M1_TAF2; TATA binding protein (TBP) associated factor 2
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q32PW3.2 GenPept UniProtKB/Swiss-Prot:Q32PW3

    Gene LinkOut

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