rad9a RAD9 checkpoint clamp component A [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: rad9aprovided by ZNC
Official Full Name: RAD9 checkpoint clamp component Aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-935
See related: Ensembl:ENSDARG00000056984 AllianceGenome:ZFIN:ZDB-GENE-040426-935
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:56197; zgc:85638
Summary: Predicted to be involved in DNA integrity checkpoint signaling; DNA repair; and cellular response to ionizing radiation. Predicted to act upstream of or within DNA damage checkpoint signaling. Predicted to be part of checkpoint clamp complex. Is expressed in head. Orthologous to human RAD9A (RAD9 checkpoint clamp component A). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (21923742..21932414, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (21626497..21635169, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA damage checkpoint signaling	IEA Inferred from Electronic Annotation more info
involved_in DNA repair	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within DNA repair	IEA Inferred from Electronic Annotation more info
involved_in DNA replication checkpoint signaling	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellular response to ionizing radiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitotic intra-S DNA damage checkpoint signaling	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of checkpoint clamp complex	IBA Inferred from Biological aspect of Ancestor more info
part_of checkpoint clamp complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cell cycle checkpoint control protein RAD9A

NP_956501.2

EC 3.1.11.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200207.2 → NP_956501.2 cell cycle checkpoint control protein RAD9A

Status: VALIDATED

Source sequence(s)

BX324205, EH548015, EH569133

UniProtKB/TrEMBL

A0A8M1PCL5, F2Z4U5

Related

ENSDARP00000054419.4, ENSDART00000054420.5

Conserved Domains (2) summary

cd00577
Location:5 → 263

PCNA; Proliferating Cell Nuclear Antigen (PCNA) domain found in eukaryotes and archaea. These polymerase processivity factors play a role in DNA replication and repair. PCNA encircles duplex DNA in its central cavity, providing a DNA-bound platform for the ...

pfam04139
Location:13 → 261

Rad9; Rad9