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    rnf11b ring finger protein 11b [ Danio rerio (zebrafish) ]

    Gene ID: 100150568, updated on 2-Nov-2024

    Summary

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    Official Symbol
    rnf11bprovided by ZNC
    Official Full Name
    ring finger protein 11bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050913-69
    See related
    Ensembl:ENSDARG00000040635 AllianceGenome:ZFIN:ZDB-GENE-050913-69
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:114095
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be part of ubiquitin ligase complex. Is expressed in several structures, including eye; neural tube; optic cup; segmental plate; and somite. Orthologous to human RNF11 (ring finger protein 11). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See rnf11b in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (16424722..16464453, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (16389010..16428741, complement)

    Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene Fas (TNFRSF6) associated factor 1 Neighboring gene cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) Neighboring gene tetratricopeptide repeat domain 39A Neighboring gene epidermal growth factor receptor pathway substrate 15

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Rnf11-like is a novel component of NF-κB signaling, governing the posterior patterning in the zebrafish embryos. Maddirevula S, et al. Biochem Biophys Res Commun, 2012 Jun 15. PMID 22609198
    2. Zebrafish dmrta2 regulates the expression of cdkn2c in spermatogenesis in the adult testis. Xu S, et al. Biol Reprod, 2013 Jan. PMID 23175770
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC114095

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RING finger protein 11b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001128408.1 → NP_001121880.1  RING finger protein 11b

      Status: PROVISIONAL

      Source sequence(s)
      CT025878
      UniProtKB/TrEMBL
      A0A8M1NHK2, B0V2S5
      Related
      ENSDARP00000089462.4, ENSDART00000098691.5
      Conserved Domains (1) summary
      cd16468
      Location:98 → 140
      RING-H2_RNF11; RING finger, H2 subclass, found in RING finger protein 11 (RNF11) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007119.7 Reference GRCz11 Primary Assembly

      Range
      16424722..16464453 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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