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    cyyr1 cysteine/tyrosine-rich 1 [ Danio rerio (zebrafish) ]

    Gene ID: 405818, updated on 2-Nov-2024

    Summary

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    Official Symbol
    cyyr1provided by ZNC
    Official Full Name
    cysteine/tyrosine-rich 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2356
    See related
    Ensembl:ENSDARG00000103783 AllianceGenome:ZFIN:ZDB-GENE-040426-2356
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:77252
    Summary
    Predicted to be located in membrane. Is expressed in several structures, including female organism; head; lateral line system; male organism; and pectoral fin. Orthologous to human CYYR1 (cysteine and tyrosine rich 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See cyyr1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (658405..669717, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (663226..674538, complement)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene ATP synthase peripheral stalk subunit F6 Neighboring gene amyloid beta (A4) precursor protein a Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif, 1 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The anti-melanogenic properties of Swietenia macrophylla king. Mahendra CK, et al. Biomed Pharmacother, 2023 Jun. PMID 37068335
    2. Cysteine and tyrosine-rich 1 (CYYR1), a novel unpredicted gene on human chromosome 21 (21q21.2), encodes a cysteine and tyrosine-rich protein and defines a new family of highly conserved vertebrate-specific genes. Vitale L, et al. Gene, 2002 May 15. PMID 12062809
    3. Identification of housekeeping genes suitable for gene expression analysis in the zebrafish. Casadei R, et al. Gene Expr Patterns, 2011 Mar-Apr. PMID 21281742
    4. Dynamic gene expression by putative hair-cell progenitors during regeneration in the zebrafish lateral line. Steiner AB, et al. Proc Natl Acad Sci U S A, 2014 Apr 8. PMID 24706895, Free PMC Article
    5. Genomewide expression profiling in the zebrafish embryo identifies target genes regulated by Hedgehog signaling during vertebrate development. Xu J, et al. Genetics, 2006 Oct. PMID 16888327, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC77252

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cysteine and tyrosine-rich protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212882.2 → NP_998047.1  cysteine and tyrosine-rich protein 1 precursor

      See identical proteins and their annotated locations for NP_998047.1

      Status: VALIDATED

      Source sequence(s)
      CT700616, FO704780
      UniProtKB/Swiss-Prot
      Q6NYG4
      Related
      ENSDARP00000134426.1, ENSDART00000160564.2
      Conserved Domains (1) summary
      pfam10873
      Location:8 → 158
      DUF2668; Protein of unknown function (DUF2668)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      658405..669717 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NYG4.1 GenPept UniProtKB/Swiss-Prot:Q6NYG4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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