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    sona SON DNA and RNA binding protein a [ Danio rerio (zebrafish) ]

    Gene ID: 792544, updated on 2-Nov-2024

    Summary

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    Official Symbol
    sonaprovided by ZNC
    Official Full Name
    SON DNA and RNA binding protein aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5845
    See related
    Ensembl:ENSDARG00000055389 AllianceGenome:ZFIN:ZDB-GENE-030131-5845
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc30f01; fi20h07; wu:fc30f01; wu:fi20h07; si:dkey-67c22.2
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in regulation of mRNA splicing, via spliceosome. Predicted to act upstream of or within regulation of RNA splicing and regulation of cell cycle. Human ortholog(s) of this gene implicated in ZTTK syndrome and congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay. Orthologous to human SON (SON DNA and RNA binding protein). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    all
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    Genomic context

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    See sona in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (35832294..35842375)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (36023109..36033190)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene neural cell adhesion molecule 2 Neighboring gene zona pellucida glycoprotein 2, like 1 Neighboring gene regulator of calcineurin 1a Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 28

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Functional characterization of Atlantic salmon (Salmo salar L.) PepT2 transporters. Vacca F, et al. J Physiol, 2022 May. PMID 35413133, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within regulation of RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC792544

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001130400.1 → NP_001123872.1  uncharacterized protein LOC792544

      See identical proteins and their annotated locations for NP_001123872.1

      Status: PREDICTED

      Source sequence(s)
      CR548635
      UniProtKB/TrEMBL
      A0A8N7UZ56, B0UYQ8
      Related
      ENSDARP00000106482.2, ENSDART00000130549.4
      Conserved Domains (2) summary
      cl25574
      Location:539 → 744
      TOP2c; TopoisomeraseII
      cl25887
      Location:704 → 815
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      35832294..35842375
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021478776.2 → XP_021334451.1  uncharacterized protein LOC792544 isoform X1

      UniProtKB/TrEMBL
      A0A8N7UZ56, B0UYQ8
      Conserved Domains (2) summary
      cl25574
      Location:539 → 744
      TOP2c; TopoisomeraseII
      cl25887
      Location:704 → 815
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394761.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      189907..200065
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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