U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cuzd1.1 CUB and zona pellucida-like domains 1, tandem duplicate 1 [ Danio rerio (zebrafish) ]

    Gene ID: 556215, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    cuzd1.1provided by ZNC
    Official Full Name
    CUB and zona pellucida-like domains 1, tandem duplicate 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-131122-16
    See related
    AllianceGenome:ZFIN:ZDB-GENE-131122-16
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb66a12; wu:fb66a12; si:ch211-208g24.5
    Summary
    Predicted to enable several functions, including RNA-DNA hybrid ribonuclease activity; RNA-directed DNA polymerase activity; and zinc ion binding activity. Predicted to act upstream of or within DNA integration and proteolysis. Predicted to be active in cell surface and extracellular space. Orthologous to human CUZD1 (CUB and zona pellucida like domains 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See cuzd1.1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (21871978..21877466, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (21850204..21860189, complement)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene CUB and zona pellucida-like domains 1, tandem duplicate 2 Neighboring gene CUB and zona pellucida-like domain-containing protein 1 Neighboring gene CUB and zona pellucida-like domain-containing protein 1 Neighboring gene pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a Neighboring gene HtrA serine peptidase 1a

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA-DNA hybrid ribonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA-directed DNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables aspartic-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA integration IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    retrovirus-related Pol polyprotein from transposon opus

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      21871978..21877466 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021467402.2 → XP_021323077.1  retrovirus-related Pol polyprotein from transposon opus

      UniProtKB/TrEMBL
      A0A8M9P0J8
      Conserved Domains (4) summary
      COG2801
      Location:1252 → 1486
      Tra5; Transposase InsO and inactivated derivatives [Mobilome: prophages, transposons]
      cd01647
      Location:745 → 921
      RT_LTR; Reverse transcriptases (RTs) from retrotransposons and retroviruses which have long terminal repeats (LTRs) in their DNA copies but not in their RNA template. RT catalyzes DNA replication from an RNA template, and is responsible for the replication of ...
      cd09274
      Location:1021 → 1143
      RNase_HI_RT_Ty3; Ty3/Gypsy family of RNase HI in long-term repeat retroelements
      pfam00665
      Location:1342 → 1454
      rve; Integrase core domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials