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    gps1 G protein pathway suppressor 1 [ Danio rerio (zebrafish) ]

    Gene ID: 777711, updated on 14-Nov-2024

    Summary

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    Official Symbol
    gps1provided by ZNC
    Official Full Name
    G protein pathway suppressor 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041111-240
    See related
    Ensembl:ENSDARG00000040650 AllianceGenome:ZFIN:ZDB-GENE-041111-240
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:6909260; im:7145572; zgc:154082
    Summary
    Predicted to be located in cytoplasm. Predicted to be part of COP9 signalosome. Orthologous to human GPS1 (G protein pathway suppressor 1). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See gps1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (36234059..36246814, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (36104461..36117301, complement)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene casein kinase 1, delta a Neighboring gene dihydrouridine synthase 1-like (S. cerevisiae) Neighboring gene Rac family small GTPase 3a Neighboring gene protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolutionary emergence of the rac3b/rfng/sgca regulatory cluster refined mechanisms for hindbrain boundaries formation. Letelier J, et al. Proc Natl Acad Sci U S A, 2018 Apr 17. PMID 29610331, Free PMC Article
    2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    COP9 signalosome complex subunit 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077759.1 → NP_001071227.1  COP9 signalosome complex subunit 1

      See identical proteins and their annotated locations for NP_001071227.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124805
      UniProtKB/TrEMBL
      A0AUR9, B2GSQ6, F6NZW4
      Related
      ENSDARP00000059505.3, ENSDART00000059506.5
      Conserved Domains (2) summary
      pfam01399
      Location:320 → 424
      PCI; PCI domain
      pfam10602
      Location:123 → 305
      RPN7; 26S proteasome subunit RPN7

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      36234059..36246814 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005164049.5 → XP_005164106.1  COP9 signalosome complex subunit 1 isoform X3

      UniProtKB/TrEMBL
      A0A8M2BB76
      Conserved Domains (2) summary
      pfam01399
      Location:320 → 424
      PCI; PCI domain
      pfam10602
      Location:123 → 305
      RPN7; 26S proteasome subunit RPN7

    2. XM_021471590.2 → XP_021327265.1  COP9 signalosome complex subunit 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9Q1J0
      Conserved Domains (2) summary
      pfam01399
      Location:360 → 464
      PCI; PCI domain
      pfam10602
      Location:163 → 345
      RPN7; 26S proteasome subunit RPN7

    3. XM_068217682.1 → XP_068073783.1  COP9 signalosome complex subunit 1 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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