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    med21 mediator complex subunit 21 [ Danio rerio (zebrafish) ]

    Gene ID: 406732, updated on 2-Nov-2024

    Summary

    Official Symbol
    med21provided by ZNC
    Official Full Name
    mediator complex subunit 21provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2763
    See related
    Ensembl:ENSDARG00000026839 AllianceGenome:ZFIN:ZDB-GENE-040426-2763
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    surb7; fk48d02; zgc:56532; wu:fk48d02
    Summary
    Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of mediator complex. Orthologous to human MED21 (mediator complex subunit 21). [provided by Alliance of Genome Resources, Nov 2024]
    Orthologs
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    Genomic context

    See med21 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (1757487..1759555)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (1908174..1910242)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene FGFR1 oncogene partner 2 Neighboring gene transmembrane 7 superfamily member 3 Neighboring gene peptidase, mitochondrial processing subunit beta Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 2 Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 4b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mediator complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mediator of RNA polymerase II transcription subunit 21
    Names
    RNA polymerase II holoenzyme component SRB7
    RNAPII complex component SRB7
    SRB7 suppressor of RNA polymerase B homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213423.1NP_998588.1  mediator of RNA polymerase II transcription subunit 21

      See identical proteins and their annotated locations for NP_998588.1

      Status: PROVISIONAL

      Source sequence(s)
      BC049042
      UniProtKB/Swiss-Prot
      Q7ZTI5
      Related
      ENSDARP00000036773.6, ENSDART00000032460.7
      Conserved Domains (1) summary
      pfam11221
      Location:1127
      Med21; Subunit 21 of Mediator complex

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      1757487..1759555
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)