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    cyp2aa4 cytochrome P450, family 2, subfamily AA, polypeptide 4 [ Danio rerio (zebrafish) ]

    Gene ID: 415182, updated on 14-Nov-2024

    Summary

    Official Symbol
    cyp2aa4provided by ZNC
    Official Full Name
    cytochrome P450, family 2, subfamily AA, polypeptide 4provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040625-72
    See related
    Ensembl:ENSDARG00000098803 AllianceGenome:ZFIN:ZDB-GENE-040625-72
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cyp2; zgc:86915
    Summary
    Predicted to enable heme binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be located in membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in integument and liver. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See cyp2aa4 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (42362334..42378390)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (42396841..42413002)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 2, subfamily AA, polypeptide 6 Neighboring gene cytochrome P450, family 2, subfamily AA, polypeptide 11 Neighboring gene uncharacterized LOC137489151 Neighboring gene uncharacterized LOC101887079

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables iron ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables monooxygenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002092.3NP_001002092.2  cytochrome P450 2AA4

      Status: VALIDATED

      Source sequence(s)
      FP015919
      Related
      ENSDARP00000134379.1, ENSDART00000164249.2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      42362334..42378390
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017353539.3XP_017209028.1  cytochrome P450 2AA4 isoform X1

      UniProtKB/TrEMBL
      A0A8M6YV80, Q6IQ77