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    COI1 Coi1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851989, updated on 2-Nov-2024

    Summary

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    Official Symbol
    COI1
    Official Full Name
    Coi1p
    Primary source
    SGD:S000007650
    Locus tag
    YDR381C-A
    See related
    AllianceGenome:SGD:S000007650; FungiDB:YDR381C-A; VEuPathDB:YDR381C-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MCO13
    Summary
    Involved in mitochondrial cytochrome c oxidase assembly and mitochondrial respiratory chain complex III assembly. Located in mitochondrial inner membrane. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See COI1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    2
    Sequence:
    Chromosome: IV; NC_001136.10 (1238312..1238850, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene phenylpyruvate decarboxylase ARO10 Neighboring gene RNA-binding protein YRA1 Neighboring gene ribosomal protein P2B Neighboring gene Nkp1p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Coi1 is a novel assembly factor of the yeast complex III-complex IV supercomplex. Singhal RK, et al. Mol Biol Cell, 2017 Aug 9. PMID 28794267, Free PMC Article
    2. Complete Native Stable Isotope Labeling by Amino Acids of Saccharomyces cerevisiae for Global Proteomic Analysis. Dannenmaier S, et al. Anal Chem, 2018 Sep 4. PMID 30102515, Free PMC Article
    3. Secondary structure is required for 3' splice site recognition in yeast. Gahura O, et al. Nucleic Acids Res, 2011 Dec. PMID 21893588, Free PMC Article
    4. Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale. Morgenstern M, et al. Cell Rep, 2017 Jun 27. PMID 28658629, Free PMC Article
    5. Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins. Zahedi RP, et al. Mol Biol Cell, 2006 Mar. PMID 16407407, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial cytochrome c oxidase assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitochondrial respirasome assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitochondrial respiratory chain complex III assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrial outer membrane HDA PubMed 
    located_in mitochondrial outer membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Coi1p
    NP_219495.2
    • Mitochondrial assembly factor; important for assembly of the mitochondrial respiratory chain bc1 complex (complex III), cytochrome oxidase (complex IV), and the complex III-complex IV supercomplex; embedded in the mitochondrial inner membrane, facing the intermembrane space

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      1238312..1238850 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184511.1 → NP_219495.2  TPA: Coi1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_219495.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VT15, Q3E6R5
      UniProtKB/TrEMBL
      A6ZYY2, B3LFR9, C7GMF3, C8Z5U6, G2WBC1, N1P8S4
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3E6R5.1

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