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    set9 histone lysine H4-K20 methyltransferase Set9 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539545, updated on 18-Sep-2024

    Summary

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    Official Symbol
    set9
    Official Full Name
    histone lysine H4-K20 methyltransferase Set9
    Primary source
    PomBase:SPCC4B3.12
    Locus tag
    SPOM_SPCC4B3.12
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See set9 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (1153914..1156061, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene anillin-related medial ring protein Mid1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MatE family transporter Neighboring gene ncRNA Neighboring gene protein Cwf20 Neighboring gene ncRNA Neighboring gene protein fra3 Neighboring gene inositol 1,3,4,5,6-pentakisphosphate (IP5) kinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of Set9-mediated H4K20 methylation by a PWWP domain protein. Wang Y, et al. Mol Cell, 2009 Feb 27. PMID 19250904, Free PMC Article
    2. Mdb1, a fission yeast homolog of human MDC1, modulates DNA damage response and mitotic spindle function. Wei Y, et al. PLoS One, 2014. PMID 24806815, Free PMC Article
    3. Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks. Du LL, et al. Genes Dev, 2006 Jun 15. PMID 16778077, Free PMC Article
    4. Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage. Sanders SL, et al. Cell, 2004 Nov 24. PMID 15550243
    5. Large scale screening of genetic interaction with sgf73(+) in fission yeast. Guo Y, et al. Yi Chuan, 2014 Jul. PMID 25076038

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Regulation of Set9-mediated H4K20 methylation by a PWWP domain protein
      Title: Regulation of Set9-mediated H4K20 methylation by a PWWP domain protein.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables histone H4K20 methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone H4K20 trimethyltransferase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables histone binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables nucleosome binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic G2 DNA damage checkpoint signaling IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT involved_in nucleotide-excision repair EXP
    Inferred from Experiment
    more info
    		 PubMed 
    NOT involved_in pericentric heterochromatin formation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT involved_in regulation of gene expression IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cell division site HDA PubMed 
    is_active_in chromatin IC
    Inferred by Curator
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in mitotic spindle pole body HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    histone lysine H4-K20 methyltransferase Set9

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1153914..1156061 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023070.3 → NP_588078.1  histone lysine H4-K20 methyltransferase Set9 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588078.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9USK2
      Conserved Domains (2) summary
      COG2940
      Location:1 → 430
      SET; SET domain-containing protein (function unknown) [General function prediction only]
      pfam00856
      Location:127 → 220
      SET; SET domain
    Nucleotide Protein
    Heading Accession and Version

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