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    ECM3 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854259, updated on 11-Sep-2024

    Summary

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    Official Symbol
    ECM3
    Primary source
    SGD:S000005618
    Locus tag
    YOR092W
    See related
    AllianceGenome:SGD:S000005618; FungiDB:YOR092W; VEuPathDB:YOR092W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    YOR3165W
    Summary
    Predicted to be involved in cell wall organization and transmembrane transport. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (495127..496968)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene type 2C protein phosphatase PTC5 Neighboring gene Tma46p Neighboring gene Cmr2p Neighboring gene Arf family GTPase ARF3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DNA sequencing and analysis of 130 kb from yeast chromosome XV. Voss H, et al. Yeast, 1997 Jun 15. PMID 9200815
    2. Evidence for Regulation of ECM3 Expression by Methylation of Histone H3 Lysine 4 and Intergenic Transcription in Saccharomyces cerevisiae. Raupach EA, et al. G3 (Bethesda), 2016 Sep 8. PMID 27449519, Free PMC Article
    3. Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast. Dardalhon M, et al. FEMS Yeast Res, 2007 Sep. PMID 17608707, Free PMC Article
    4. Lactic-acid stress causes vacuolar fragmentation and impairs intracellular amino-acid homeostasis in Saccharomyces cerevisiae. Suzuki T, et al. J Biosci Bioeng, 2012 Apr. PMID 22177309
    5. A Whi7-anchored loop controls the G1 Cdk-cyclin complex at start. Yahya G, et al. Mol Cell, 2014 Jan 9. PMID 24374311

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Our results are consistent with a model in which cotranscriptional methylation of histone H3 K4, mediated by the Paf1 complex and noncoding transcription, leads to activation of ECM3 transcription
      Title: Evidence for Regulation of ECM3 Expression by Methylation of Histone H3 Lysine 4 and Intergenic Transcription in Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in endoplasmic reticulum HDA PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative ATPase ECM3
    NP_014735.1
    • Non-essential hypothetical protein; involved in signal transduction and the genotoxic response; induced rapidly in response to treatment with 8-methoxypsoralen and UVA irradiation; relocalizes from ER to cytoplasm upon DNA replication stress; ECM3 has a paralog, YNL095C, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      495127..496968
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183511.1 → NP_014735.1  TPA: putative ATPase ECM3 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014735.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2F3, Q99252
      UniProtKB/TrEMBL
      A6ZNU2, B3LJD8, C8ZI53, N1NWJ6
      Conserved Domains (1) summary
      COG0679
      Location:9 → 337
      YfdV; Predicted permease [General function prediction only]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99252.1

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