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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853607, updated on 18-Sep-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000003903
    Locus tag
    YJR142W
    See related
    AllianceGenome:SGD:S000003903; FungiDB:YJR142W; VEuPathDB:YJR142W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables 8-oxo-dGDP phosphatase activity. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (697141..698169)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Hir3p Neighboring gene putative polyadenylation protein Neighboring gene dolichyl-phosphate-mannose-protein mannosyltransferase Neighboring gene Mgm101p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A cross-kingdom Nudix enzyme that pre-empts damage in thiamin metabolism. Goyer A, et al. Biochem J, 2013 Sep 15. PMID 23834287
    2. Multiple Nudix family proteins possess mRNA decapping activity. Song MG, et al. RNA, 2013 Mar. PMID 23353937, Free PMC Article
    3. Chromatin-associated genes protect the yeast genome from Ty1 insertional mutagenesis. Nyswaner KM, et al. Genetics, 2008 Jan. PMID 18202368, Free PMC Article
    4. Substrate specificity analysis of protein kinase complex Dbf2-Mob1 by peptide library and proteome array screening. Mah AS, et al. BMC Biochem, 2005 Oct 21. PMID 16242037, Free PMC Article
    5. Dissection of a complex phenotype by functional genomics reveals roles for the yeast cyclin-dependent protein kinase Pho85 in stress adaptation and cell integrity. Huang D, et al. Mol Cell Biol, 2002 Jul. PMID 12077337, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables 8-oxo-dGDP phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 8-oxo-dGDP phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_012676.3
    • 8-oxo-dGTP diphosphatase of the Nudix hydrolase family; converts diphosphates of damaged forms of thiamin to monophosphates; GST fusion protein is a Dbf2p-Mob1p phosphorylation target in a proteome chip analysis; synthetic lethal with PH085 deletion; plays a role in restricting Ty1 transposition

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      697141..698169
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181800.3 → NP_012676.3  TPA: uncharacterized protein YJR142W [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012676.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWW1, P47173
      UniProtKB/TrEMBL
      A6ZQ98, C7GM71, C8ZBU2, N1P0B7
      Conserved Domains (2) summary
      cd03676
      Location:125 → 315
      Nudix_hydrolase_3; Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belong to this superfamily requires a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly ...
      pfam15916
      Location:80 → 153
      DUF4743; Domain of unknown function (DUF4743)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P47173.1

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