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    FBLIM1 filamin binding LIM protein 1 [ Homo sapiens (human) ]

    Gene ID: 54751, updated on 10-Dec-2024

    Summary

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    Official Symbol
    FBLIM1provided by HGNC
    Official Full Name
    filamin binding LIM protein 1provided by HGNC
    Primary source
    HGNC:HGNC:24686
    See related
    Ensembl:ENSG00000162458 MIM:607747; AllianceGenome:HGNC:24686
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CAL; FBLP1; FBLP-1
    Summary
    This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
    Expression
    Broad expression in gall bladder (RPKM 17.5), colon (RPKM 14.6) and 22 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See FBLIM1 in Genome Data Viewer
    Location:
    1p36.21
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (15756638..15786589)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (15201378..15231333)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (16083133..16113084)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene SLC25A34 and TMEM82 antisense RNA 1 Neighboring gene solute carrier family 25 member 34 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 245 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:16068575-16069355 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16070316-16070829 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16070830-16071342 Neighboring gene transmembrane protein 82 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:16079899-16080400 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:16080401-16080900 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:16082643-16083422 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16087099-16088043 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16112886-16113650 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:16113651-16114415 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:16118272-16118772 Neighboring gene ribosomal protein L12 pseudogene 14 Neighboring gene Sharpr-MPRA regulatory region 12316 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:16130189-16130690 Neighboring gene ubiquinol-cytochrome c reductase hinge protein like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Migfilin and filamin as regulators of integrin activation in endothelial cells and neutrophils. Das M, et al. PLoS One, 2011. PMID 22043318, Free PMC Article
    2. High prevalence of rare FBLIM1 gene variants in an Italian cohort of patients with Chronic Non-bacterial Osteomyelitis (CNO). d'Adamo AP, et al. Pediatr Rheumatol Online J, 2020 Jul 10. PMID 32650789, Free PMC Article
    3. Genetic variants in FBLIM1 gene do not contribute to SAPHO syndrome and chronic recurrent multifocal osteomyelitis in typical patient groups. Assmann G, et al. BMC Med Genet, 2020 May 12. PMID 32397996, Free PMC Article
    4. Physical and functional association of migfilin with cell-cell adhesions. Gkretsi V, et al. J Cell Sci, 2005 Feb 15. PMID 15671069
    5. Migfilin and its binding partners: from cell biology to human diseases. Wu C. J Cell Sci, 2005 Feb 15. PMID 15701922

    See all (51) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. High prevalence of rare FBLIM1 gene variants in an Italian cohort of patients with Chronic Non-bacterial Osteomyelitis (CNO).
      Title: High prevalence of rare FBLIM1 gene variants in an Italian cohort of patients with Chronic Non-bacterial Osteomyelitis (CNO).
    2. Genetic analyses of FBLIM1 did not provide evidence that this gene is relevant in our patient group. Our study indicates the need to elucidate SAPHO's and CRMO/CNO's pathogenesis.
      Title: Genetic variants in FBLIM1 gene do not contribute to SAPHO syndrome and chronic recurrent multifocal osteomyelitis in typical patient groups.
    3. Findings indicate that tightly regulated expression of migfilin is essential for neuronal development and that FBLIM1 disruption may be related to the phenotypes associated with ASD and related neurodevelopmental disorders.
      Title: Possible involvement of a cell adhesion molecule, Migfilin, in brain development and pathogenesis of autism spectrum disorders.
    4. Results showed FBLIM1 overexpression in oral squamous cell carcinoma (OSCC) in vitro and in vivo and that FBLIM1 positivity in OSCC was correlated with tumoral growth and vascular invasion. FBLIM1 silencing was characterized by decreased cellular growth, invasiveness, and migratory activities and induced EGFR down-regulation.
      Title: FBLIM1 enhances oral cancer malignancy via modulation of the epidermal growth factor receptor pathway.
    5. Authors conclude that circFBLIM1 may function as a competing endogenous RNA (ceRNA) to regulate FBLIM1 expression through sponging miR-346 to exert regulatory functions in HCC.
      Title: circFBLIM1 act as a ceRNA to promote hepatocellular cancer progression by sponging miR-346.
    6. Migfilin promotes migration and invasion in glioma by driving EGFR and MMP-2 signalings
      Title: Migfilin promotes migration and invasion in glioma by driving EGFR and MMP-2 signalings: A positive feedback loop regulation.
    7. data implicate FBLIM1 in the pathogenesis of sterile bone inflammation and our findings suggest CRMO is a disorder of chronic inflammation and imbalanced bone remodeling
      Title: Recessive coding and regulatory mutations in FBLIM1 underlie the pathogenesis of chronic recurrent multifocal osteomyelitis (CRMO).
    8. the present study emphasizes for the first time to our knowledge the role of Migfilin in osteoarthritis(OA) and highlights the importance of cell-ECM adhesion proteins in OA pathogenesis.
      Title: Migfilin's elimination from osteoarthritic chondrocytes further promotes the osteoarthritic phenotype via β-catenin upregulation.
    9. Migfilin expression is reduced in breast cancer.
      Title: Mitogen-inducible Gene-2 (MIG2) and migfilin expression is reduced in samples of human breast cancer.
    10. alpha-parvin, beta-parvin and migfilin were expressed in tumor cells in 53%, 2%, 28% and 53% of effusions and 57%, 20%, 83% and 25% of solid lesions, respectively.
      Title: Migfilin, α-parvin and β-parvin are differentially expressed in ovarian serous carcinoma effusions, primary tumors and solid metastases.
    Submit: New GeneRIF Correction See all GeneRIFs (21)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Association of genome-wide variation with highly sensitive cardiac troponin-T levels in European Americans and Blacks: a meta-analysis from atherosclerosis risk in communities and cardiovascular health studies.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    HIV-1 interactions

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    Replication interactions

    Interaction Pubs
    Knockdown of filamin binding LIM protein 1 (FBLIM1) by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1 PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • DKFZp434G171

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables filamin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables filamin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell-cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of integrin activation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell junction IDA
    Inferred from Direct Assay
    more info
    		  
    located_in cell periphery IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in fibrillar center IDA
    Inferred from Direct Assay
    more info
    		  
    located_in focal adhesion HDA PubMed 
    is_active_in focal adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in focal adhesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in stress fiber IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in stress fiber IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    filamin-binding LIM protein 1
    Names
    CSX-associated LIM
    MIG2-interacting protein
    migfilin
    mitogen-inducible 2 interacting protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024215.1 → NP_001019386.1  filamin-binding LIM protein 1 isoform b

      See identical proteins and their annotated locations for NP_001019386.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks multiple 3' exons and contains an extra segment with an early stop codon, compared to variant 1. The encoded protein (isoform b) is longer and has a distinct C-terminus, compared to isoform a.
      Source sequence(s)
      AF459643, AL450998, CN278745
      Consensus CDS
      CCDS44064.1
      UniProtKB/Swiss-Prot
      Q8WUP2
      Related
      ENSP00000416387.2, ENST00000441801.6
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cd08368
      Location:183 → 236
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    2. NM_001024216.3 → NP_001019387.1  filamin-binding LIM protein 1 isoform c

      See identical proteins and their annotated locations for NP_001019387.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks multiple alternate in-frame exons, compared to variant 1, resulting in a shorter protein (isoform c), compared to isoform a.
      Source sequence(s)
      AK027444, AK055259, AL133035, AW069718
      Consensus CDS
      CCDS30609.1
      UniProtKB/Swiss-Prot
      Q8WUP2
      Related
      ENSP00000364920.2, ENST00000332305.5
      Conserved Domains (2) summary
      cd09372
      Location:146 → 198
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cl02475
      Location:206 → 267
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    3. NM_001350151.2 → NP_001337080.1  filamin-binding LIM protein 1 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1 and 4 encode the same protein (isoform a).
      Source sequence(s)
      AL133035, AL450998, AW069718, BC019895
      Consensus CDS
      CCDS163.1
      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6
      Related
      ENSP00000364926.1, ENST00000375771.5
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cl02475
      Location:303 → 364
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    4. NM_017556.4 → NP_060026.2  filamin-binding LIM protein 1 isoform a

      See identical proteins and their annotated locations for NP_060026.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes isoform a. Variants 1 and 4 encode the same protein (isoform a).
      Source sequence(s)
      AK055259, AL133035, AW069718
      Consensus CDS
      CCDS163.1
      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6
      Related
      ENSP00000364921.3, ENST00000375766.8
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cl02475
      Location:303 → 364
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      15756638..15786589
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047423104.1 → XP_047279060.1  filamin-binding LIM protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6

    2. XM_011541617.3 → XP_011539919.1  filamin-binding LIM protein 1 isoform X2

      See identical proteins and their annotated locations for XP_011539919.1

      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cl02475
      Location:303 → 364
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    3. XM_047423129.1 → XP_047279085.1  filamin-binding LIM protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6

    4. XM_047423148.1 → XP_047279104.1  filamin-binding LIM protein 1 isoform X4

    5. XM_047423110.1 → XP_047279066.1  filamin-binding LIM protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6

    6. XM_047423162.1 → XP_047279118.1  filamin-binding LIM protein 1 isoform X5

    7. XM_017001526.3 → XP_016857015.1  filamin-binding LIM protein 1 isoform X5

    8. XM_047423159.1 → XP_047279115.1  filamin-binding LIM protein 1 isoform X5

    9. XM_005245903.2 → XP_005245960.1  filamin-binding LIM protein 1 isoform X1

      See identical proteins and their annotated locations for XP_005245960.1

      UniProtKB/Swiss-Prot
      Q8WUP2
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cd08368
      Location:183 → 236
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    10. XM_006710705.2 → XP_006710768.1  filamin-binding LIM protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006710768.1

      UniProtKB/Swiss-Prot
      Q8WUP2
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cd08368
      Location:183 → 236
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    11. XM_017001521.3 → XP_016857010.1  filamin-binding LIM protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q8WUP2
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cd08368
      Location:183 → 236
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    12. XM_017001519.3 → XP_016857008.1  filamin-binding LIM protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q8WUP2
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cd08368
      Location:183 → 236
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    13. XM_006710704.4 → XP_006710767.1  filamin-binding LIM protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006710767.1

      UniProtKB/Swiss-Prot
      Q8WUP2
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cd08368
      Location:183 → 236
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    14. XM_017001520.3 → XP_016857009.1  filamin-binding LIM protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q8WUP2
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cd08368
      Location:183 → 236
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    15. XM_011541616.3 → XP_011539918.1  filamin-binding LIM protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011539918.1

      UniProtKB/Swiss-Prot
      Q8WUP2
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cd08368
      Location:183 → 236
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    16. XM_017001525.2 → XP_016857014.1  filamin-binding LIM protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cl02475
      Location:303 → 364
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    17. XM_047423112.1 → XP_047279068.1  filamin-binding LIM protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6

    18. XM_047423149.1 → XP_047279105.1  filamin-binding LIM protein 1 isoform X4

    19. XM_047423133.1 → XP_047279089.1  filamin-binding LIM protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6

    20. XM_047423116.1 → XP_047279072.1  filamin-binding LIM protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6

    21. XM_047423128.1 → XP_047279084.1  filamin-binding LIM protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6

    22. XM_047423151.1 → XP_047279107.1  filamin-binding LIM protein 1 isoform X4

    23. XM_047423138.1 → XP_047279094.1  filamin-binding LIM protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6

    24. XM_005245902.2 → XP_005245959.1  filamin-binding LIM protein 1 isoform X1

      See identical proteins and their annotated locations for XP_005245959.1

      UniProtKB/Swiss-Prot
      Q8WUP2
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cd08368
      Location:183 → 236
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    25. XM_047423123.1 → XP_047279079.1  filamin-binding LIM protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6

    26. XM_047423158.1 → XP_047279114.1  filamin-binding LIM protein 1 isoform X4

    27. XM_047423143.1 → XP_047279099.1  filamin-binding LIM protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6

    28. XM_047423152.1 → XP_047279108.1  filamin-binding LIM protein 1 isoform X4

    29. XM_047423150.1 → XP_047279106.1  filamin-binding LIM protein 1 isoform X4

    30. XM_047423141.1 → XP_047279097.1  filamin-binding LIM protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B3KNY0, Q5VVE0, Q5VVE1, Q8IX23, Q8WUP2, Q96T00, Q9UFD6

    31. XM_047423156.1 → XP_047279112.1  filamin-binding LIM protein 1 isoform X4

    32. XM_047423172.1 → XP_047279128.1  filamin-binding LIM protein 1 isoform X5

    33. XM_047423176.1 → XP_047279132.1  filamin-binding LIM protein 1 isoform X5

    34. XM_047423147.1 → XP_047279103.1  filamin-binding LIM protein 1 isoform X3

    35. XM_047423175.1 → XP_047279131.1  filamin-binding LIM protein 1 isoform X5

    36. XM_005245900.2 → XP_005245957.1  filamin-binding LIM protein 1 isoform X1

      See identical proteins and their annotated locations for XP_005245957.1

      UniProtKB/Swiss-Prot
      Q8WUP2
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cd08368
      Location:183 → 236
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    37. XM_017001523.2 → XP_016857012.1  filamin-binding LIM protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q8WUP2
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cd08368
      Location:183 → 236
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    38. XM_005245901.2 → XP_005245958.1  filamin-binding LIM protein 1 isoform X1

      See identical proteins and their annotated locations for XP_005245958.1

      UniProtKB/Swiss-Prot
      Q8WUP2
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cd08368
      Location:183 → 236
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    39. XM_017001524.2 → XP_016857013.1  filamin-binding LIM protein 1 isoform X1

      UniProtKB/Swiss-Prot
      Q8WUP2
      Conserved Domains (2) summary
      cd09372
      Location:243 → 295
      LIM2_FBLP-1; The second LIM domain of the filamin-binding LIM protein-1 (FBLP-1)
      cd08368
      Location:183 → 236
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      15201378..15231333
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054337177.1 → XP_054193152.1  filamin-binding LIM protein 1 isoform X2

    2. XM_054337185.1 → XP_054193160.1  filamin-binding LIM protein 1 isoform X2

    3. XM_054337191.1 → XP_054193166.1  filamin-binding LIM protein 1 isoform X4

    4. XM_054337200.1 → XP_054193175.1  filamin-binding LIM protein 1 isoform X5

    5. XM_054337198.1 → XP_054193173.1  filamin-binding LIM protein 1 isoform X5

    6. XM_054337199.1 → XP_054193174.1  filamin-binding LIM protein 1 isoform X5

    7. XM_054337168.1 → XP_054193143.1  filamin-binding LIM protein 1 isoform X1

    8. XM_054337170.1 → XP_054193145.1  filamin-binding LIM protein 1 isoform X1

    9. XM_054337175.1 → XP_054193150.1  filamin-binding LIM protein 1 isoform X1

    10. XM_054337173.1 → XP_054193148.1  filamin-binding LIM protein 1 isoform X1

    11. XM_054337165.1 → XP_054193140.1  filamin-binding LIM protein 1 isoform X1

    12. XM_054337174.1 → XP_054193149.1  filamin-binding LIM protein 1 isoform X1

    13. XM_054337167.1 → XP_054193142.1  filamin-binding LIM protein 1 isoform X1

    14. XM_054337178.1 → XP_054193153.1  filamin-binding LIM protein 1 isoform X2

    15. XM_054337179.1 → XP_054193154.1  filamin-binding LIM protein 1 isoform X2

    16. XM_054337181.1 → XP_054193156.1  filamin-binding LIM protein 1 isoform X2

    17. XM_054337171.1 → XP_054193146.1  filamin-binding LIM protein 1 isoform X1

    18. XM_054337182.1 → XP_054193157.1  filamin-binding LIM protein 1 isoform X2

    19. XM_054337192.1 → XP_054193167.1  filamin-binding LIM protein 1 isoform X4

    20. XM_054337194.1 → XP_054193169.1  filamin-binding LIM protein 1 isoform X4

    21. XM_054337180.1 → XP_054193155.1  filamin-binding LIM protein 1 isoform X2

    22. XM_054337184.1 → XP_054193159.1  filamin-binding LIM protein 1 isoform X2

    23. XM_054337186.1 → XP_054193161.1  filamin-binding LIM protein 1 isoform X2

    24. XM_054337187.1 → XP_054193162.1  filamin-binding LIM protein 1 isoform X2

    25. XM_054337183.1 → XP_054193158.1  filamin-binding LIM protein 1 isoform X2

    26. XM_054337197.1 → XP_054193172.1  filamin-binding LIM protein 1 isoform X4

    27. XM_054337189.1 → XP_054193164.1  filamin-binding LIM protein 1 isoform X2

    28. XM_054337195.1 → XP_054193170.1  filamin-binding LIM protein 1 isoform X4

    29. XM_054337193.1 → XP_054193168.1  filamin-binding LIM protein 1 isoform X4

    30. XM_054337188.1 → XP_054193163.1  filamin-binding LIM protein 1 isoform X2

    31. XM_054337196.1 → XP_054193171.1  filamin-binding LIM protein 1 isoform X4

    32. XM_054337201.1 → XP_054193176.1  filamin-binding LIM protein 1 isoform X5

    33. XM_054337203.1 → XP_054193178.1  filamin-binding LIM protein 1 isoform X5

    34. XM_054337190.1 → XP_054193165.1  filamin-binding LIM protein 1 isoform X3

    35. XM_054337202.1 → XP_054193177.1  filamin-binding LIM protein 1 isoform X5

    36. XM_054337166.1 → XP_054193141.1  filamin-binding LIM protein 1 isoform X1

    37. XM_054337176.1 → XP_054193151.1  filamin-binding LIM protein 1 isoform X1

    38. XM_054337169.1 → XP_054193144.1  filamin-binding LIM protein 1 isoform X1

    39. XM_054337172.1 → XP_054193147.1  filamin-binding LIM protein 1 isoform X1

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8WUP2.2 GenPept UniProtKB/Swiss-Prot:Q8WUP2

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