itih3a.1 inter-alpha-trypsin inhibitor heavy chain 3a, tandem duplicate 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: itih3a.1provided by ZNC
Official Full Name: inter-alpha-trypsin inhibitor heavy chain 3a, tandem duplicate 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-050522-262
See related: Ensembl:ENSDARG00000055036 AllianceGenome:ZFIN:ZDB-GENE-050522-262
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: itih3a; zgc:110377
Summary: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to act upstream of or within hyaluronan metabolic process and negative regulation of peptidase activity. Predicted to be located in extracellular region. Is expressed in liver. Orthologous to human ITIH3 (inter-alpha-trypsin inhibitor heavy chain 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 11

Exon count:: 22

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (3614326..3629203, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (3594939..3609816, complement)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables peptidase inhibitor activity	IEA Inferred from Electronic Annotation more info
enables serine-type endopeptidase inhibitor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within hyaluronan metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of peptidase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: inter-alpha-trypsin inhibitor heavy chain H3a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.