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    pop4 POP4 homolog, ribonuclease P/MRP subunit [ Danio rerio (zebrafish) ]

    Gene ID: 553787, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pop4provided by ZNC
    Official Full Name
    POP4 homolog, ribonuclease P/MRP subunitprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-505
    See related
    Ensembl:ENSDARG00000101472 AllianceGenome:ZFIN:ZDB-GENE-050522-505
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:110597
    Summary
    Predicted to enable ribonuclease P RNA binding activity. Predicted to be involved in rRNA processing. Predicted to act upstream of or within tRNA 5'-leader removal. Predicted to be located in nucleolus. Predicted to be part of ribonuclease MRP complex and ribonuclease P complex. Orthologous to human POP4 (POP4 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See pop4 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (45963767..45971641)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (45691383..45699271)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene si:ch73-226i7.1 Neighboring gene uncharacterized LOC137490303 Neighboring gene uncharacterized LOC108190704 Neighboring gene pleckstrin homology domain containing, family F (with FYVE domain) member 1 Neighboring gene si:ch211-260e23.7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Inventory and analysis of the protein subunits of the ribonucleases P and MRP provides further evidence of homology between the yeast and human enzymes. Rosenblad MA, et al. Nucleic Acids Res, 2006. PMID 16998185, Free PMC Article
    2. ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis. Krens SF, et al. BMC Genomics, 2008 Apr 28. PMID 18442396, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC110597

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribonuclease P RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ribonuclease P RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within tRNA 5'-leader removal IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonuclease MRP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonuclease MRP complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonuclease P complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonuclease P complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribonuclease P protein subunit p29
    Names
    processing of precursor 4, ribonuclease P/MRP subunit
    NP_001018585.1
    XP_005166512.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001020749.2 → NP_001018585.1  ribonuclease P protein subunit p29

      See identical proteins and their annotated locations for NP_001018585.1

      Status: PROVISIONAL

      Source sequence(s)
      BC095328
      UniProtKB/TrEMBL
      Q503H3
      Related
      ENSDARP00000137725.1, ENSDART00000163098.2
      Conserved Domains (1) summary
      pfam01868
      Location:127 → 209
      UPF0086; Domain of unknown function UPF0086

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      45963767..45971641
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005166455.5 → XP_005166512.1  ribonuclease P protein subunit p29 isoform X1

      UniProtKB/TrEMBL
      A0A8M2BDV0
      Conserved Domains (1) summary
      pfam01868
      Location:86 → 168
      UPF0086; Domain of unknown function UPF0086

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394709.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      43895..51765
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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