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    coa3b cytochrome C oxidase assembly factor 3b [ Danio rerio (zebrafish) ]

    Gene ID: 335493, updated on 4-Jan-2025

    Summary

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    Official Symbol
    coa3bprovided by ZNC
    Official Full Name
    cytochrome C oxidase assembly factor 3bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-7433
    See related
    Ensembl:ENSDARG00000097456 AllianceGenome:ZFIN:ZDB-GENE-030131-7433
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fj17c03; wu:fj17c03; zgc:194167
    Summary
    Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in membrane and mitochondrion. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 14. Orthologous to human COA3 (cytochrome c oxidase assembly factor 3). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    all
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    Genomic context

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    See coa3b in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (22426714..22432427)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (22296166..22301879)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene interferon phi 1 Neighboring gene Rho GTPase activating protein 27, like Neighboring gene uncharacterized LOC110439080 Neighboring gene WNK lysine deficient protein kinase 4b Neighboring gene tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in mitochondrial cytochrome c oxidase assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within mitochondrial cytochrome c oxidase assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome C oxidase assembly factor 3b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001204250.2 → NP_001191179.2  cytochrome C oxidase assembly factor 3b

      Status: VALIDATED

      Source sequence(s)
      EH467268, EH549782
      UniProtKB/TrEMBL
      A0A8M1P1U6, X1WFF5
      Related
      ENSDARP00000128959.1, ENSDART00000154966.2
      Conserved Domains (1) summary
      pfam09813
      Location:36 → 102
      Coiled-coil_56; Coiled-coil domain-containing protein 56

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      22426714..22432427
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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