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    Uqcc4 ubiquinol-cytochrome c reductase complex assembly factor 4 [ Mus musculus (house mouse) ]

    Gene ID: 214489, updated on 28-Oct-2024

    Summary

    Official Symbol
    Uqcc4provided by MGI
    Official Full Name
    ubiquinol-cytochrome c reductase complex assembly factor 4provided by MGI
    Primary source
    MGI:MGI:2670966
    See related
    Ensembl:ENSMUSG00000067722 AllianceGenome:MGI:2670966
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ccsmst1
    Summary
    Involved in mitochondrial respiratory chain complex III assembly. Located in mitochondrial inner membrane. Orthologous to human UQCC4 (ubiquinol-cytochrome c reductase complex assembly factor 4). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 12.3), adrenal adult (RPKM 10.5) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Uqcc4 in Genome Data Viewer
    Location:
    17 A3.3; 17 12.53 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (25403535..25406636)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (25184561..25187662)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene chloride channel, voltage-sensitive 7 Neighboring gene microRNA 12188 Neighboring gene coiled-coil domain containing 154 Neighboring gene intestine-critical region regulatory element Neighboring gene proline and glutamate rich with coiled coil 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:25321285-25321526 Neighboring gene predicted gene, 52286 Neighboring gene unkempt family like zinc finger Neighboring gene N-acetylglucosamine-1-phosphotransferase, gamma subunit Neighboring gene TSR3 20S rRNA accumulation

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Clone Names

    • MGC7403

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in mitochondrial respiratory chain complex III assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitochondrial respiratory chain complex III assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ubiquinol-cytochrome c reductase complex assembly factor 4
    Names
    protein CCSMST1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183150.2NP_898973.2  ubiquinol-cytochrome c reductase complex assembly factor 4 precursor

      See identical proteins and their annotated locations for NP_898973.2

      Status: VALIDATED

      Source sequence(s)
      AC130711, BC094389, BY262222
      Consensus CDS
      CCDS57057.1
      UniProtKB/Swiss-Prot
      Q6RUT7
      Related
      ENSMUSP00000137122.2, ENSMUST00000088307.5
      Conserved Domains (2) summary
      pfam04697
      Location:761
      Pinin_SDK_N; pinin/SDK conserved region
      pfam15013
      Location:49111
      CCSMST1; CCSMST1 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      25403535..25406636
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)