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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_050771.1 RefSeqGene
- Range
-
5055..29080
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_004526.4 → NP_004517.2 DNA replication licensing factor MCM2
See identical proteins and their annotated locations for NP_004517.2
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes a functional protein.
- Source sequence(s)
-
BC007938, DB100427
- Consensus CDS
-
CCDS3043.1
- UniProtKB/Swiss-Prot
- P49736, Q14577, Q15023, Q8N2V1, Q969W7, Q96AE1, Q9BRM7
- UniProtKB/TrEMBL
-
B7Z8Z6
- Related
- ENSP00000265056.7, ENST00000265056.12
- Conserved Domains (3) summary
-
- smart00350
Location:291 → 803
- MCM; minichromosome maintenance proteins
- pfam12619
Location:73 → 182
- MCM2_N; Mini-chromosome maintenance protein 2
- pfam14551
Location:197 → 286
- MCM_N; MCM N-terminal domain
RNA
-
NR_073375.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) has an additional segment in the 5' region, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AK299934, BC000300
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000003.12 Reference GRCh38.p14 Primary Assembly
- Range
-
127598411..127622436
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_024453531.2 → XP_024309299.1 DNA replication licensing factor MCM2 isoform X1
- UniProtKB/TrEMBL
-
B7Z8Z6
- Conserved Domains (3) summary
-
- smart00350
Location:282 → 794
- MCM; minichromosome maintenance proteins
- pfam12619
Location:64 → 173
- MCM2_N; Mini-chromosome maintenance protein 2
- pfam14551
Location:190 → 278
- MCM_N; MCM N-terminal domain
Alternate T2T-CHM13v2.0
Genomic
-
NC_060927.1 Alternate T2T-CHM13v2.0
- Range
-
130333077..130357098
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054346560.1 → XP_054202535.1 DNA replication licensing factor MCM2 isoform X1
- UniProtKB/TrEMBL
-
B7Z8Z6