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    MIR455 microRNA 455 [ Homo sapiens (human) ]

    Gene ID: 619556, updated on 10-Dec-2024

    Summary

    Official Symbol
    MIR455provided by HGNC
    Official Full Name
    microRNA 455provided by HGNC
    Primary source
    HGNC:HGNC:32344
    See related
    Ensembl:ENSG00000207726 miRBase:MI0003513; AllianceGenome:HGNC:32344
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MIRN455; mir-455; hsa-mir-455
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
    Orthologs
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    Genomic context

    See MIR455 in Genome Data Viewer
    Location:
    9q32
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (114209434..114209529)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (126408154..126408249)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (116971714..116971809)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902251 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:116861361-116861896 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20208 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:116875188-116875688 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:116875689-116876189 Neighboring gene kinesin family member 12 Neighboring gene Sharpr-MPRA regulatory region 2704 Neighboring gene uncharacterized LOC105376225 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:116915624-116916145 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 20209 Neighboring gene Sharpr-MPRA regulatory region 14358 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:116925428-116925944 Neighboring gene collagen type XXVII alpha 1 chain Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:116978156-116978656 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:116980984-116981982 Neighboring gene NANOG hESC enhancer GRCh37_chr9:116986380-116986932 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:116994231-116994732 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:116994733-116995232 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:116997162-116997662 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:116997663-116998163 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_106356 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr9:117038878-117040077 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:117043569-117044381 Neighboring gene uncharacterized LOC124902252 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr9:117050487-117051686 Neighboring gene uncharacterized LOC105376224 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:117068890-117069390 Neighboring gene H3K27ac hESC enhancer GRCh37_chr9:117069391-117069891 Neighboring gene Sharpr-MPRA regulatory region 10745

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_030255.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AL445543
      Related
      ENST00000384993.3

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      114209434..114209529
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      126408154..126408249
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)