U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    KLHL34 kelch like family member 34 [ Homo sapiens (human) ]

    Gene ID: 257240, updated on 9-Dec-2024

    Summary

    Official Symbol
    KLHL34provided by HGNC
    Official Full Name
    kelch like family member 34provided by HGNC
    Primary source
    HGNC:HGNC:26634
    See related
    Ensembl:ENSG00000185915 AllianceGenome:HGNC:26634
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    Located in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See KLHL34 in Genome Data Viewer
    Location:
    Xp22.12
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (21654690..21658330, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (21238012..21241652, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (21672808..21676448, complement)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105373146 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:21357913-21358412 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:21391460-21391960 Neighboring gene H3K4me1 hESC enhancer GRCh37_chrX:21391961-21392461 Neighboring gene connector enhancer of kinase suppressor of Ras 2 Neighboring gene retinoic acid receptor responder 2 pseudogene 3 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chrX:21704726-21705925 Neighboring gene small muscle protein X-linked Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29485 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29486 Neighboring gene membrane bound transcription factor peptidase, site 2 Neighboring gene YY2 transcription factor

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    kelch-like protein 34
    Names
    RP11-450P7.3
    kelch-like 34

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153270.3NP_695002.1  kelch-like protein 34

      See identical proteins and their annotated locations for NP_695002.1

      Status: VALIDATED

      Source sequence(s)
      AI792176, AL772392, BC109031, DA395149
      Consensus CDS
      CCDS14199.1
      UniProtKB/Swiss-Prot
      Q8N239
      Related
      ENSP00000368813.2, ENST00000379499.3
      Conserved Domains (3) summary
      sd00038
      Location:358411
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:19126
      BTB; BTB/POZ domain
      cl28614
      Location:29603
      BTB; Broad-Complex, Tramtrack and Bric a brac

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      21654690..21658330 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      21238012..21241652 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)