TRPV4 transient receptor potential cation channel subfamily V member 4 [Homo sapiens (human)] - Gene

Summary

Official Symbol: TRPV4provided by HGNC
Official Full Name: transient receptor potential cation channel subfamily V member 4provided by HGNC
Primary source: HGNC:HGNC:18083
See related: Ensembl:ENSG00000111199 MIM:605427; AllianceGenome:HGNC:18083
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: SMAL; VRL2; BCYM3; CMT2C; SPSMA; TRP12; VROAC; HMSN2C; OTRPC4; SSQTL1
Summary: This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Expression: Broad expression in kidney (RPKM 5.7), salivary gland (RPKM 3.0) and 14 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 12q24.11

Exon count:: 18

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	12	NC_000012.12 (109783087..109833398, complement)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	12	NC_060936.1 (109758559..109808862, complement)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	12	NC_000012.11 (110220892..110271203, complement)

Chromosome 12 - NC_000012.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

TRPV4 Regulates the Macrophage Metabolic Response to Limit Sepsis-induced Lung Injury.
Title: TRPV4 Regulates the Macrophage Metabolic Response to Limit Sepsis-induced Lung Injury.
TRPV4 activation in human corneal epithelial cells promotes membrane mucin production.
Title: TRPV4 activation in human corneal epithelial cells promotes membrane mucin production.
TRPV4 mediates IL-1-induced Ca[2+] signaling, ERK activation and MMP expression.
Title: TRPV4 mediates IL-1-induced Ca(2+) signaling, ERK activation and MMP expression.
Impact of TRP Channels on Extracellular Matrix Remodeling: Focus on TRPV4 and Collagen.
Title: Impact of TRP Channels on Extracellular Matrix Remodeling: Focus on TRPV4 and Collagen.
Inflammation-induced TRPV4 channels exacerbate blood-brain barrier dysfunction in multiple sclerosis.
Title: Inflammation-induced TRPV4 channels exacerbate blood-brain barrier dysfunction in multiple sclerosis.
Inflammation, lipid dysregulation, and transient receptor potential cation channel subfamily V member 4 signaling perpetuate chronic vulvar pain.
Title: Inflammation, lipid dysregulation, and transient receptor potential cation channel subfamily V member 4 signaling perpetuate chronic vulvar pain.
TRPV4 in adipose tissue ameliorates diet-induced obesity by promoting white adipocyte browning.
Title: TRPV4 in adipose tissue ameliorates diet-induced obesity by promoting white adipocyte browning.
Hypothermia Attenuates Neurotoxic Microglial Activation via TRPV4.
Title: Hypothermia Attenuates Neurotoxic Microglial Activation via TRPV4.
Fatty acid metabolism promotes TRPV4 activity in lung microvascular endothelial cells in pulmonary arterial hypertension.
Title: Fatty acid metabolism promotes TRPV4 activity in lung microvascular endothelial cells in pulmonary arterial hypertension.
TRPV4 Regulates the Development of Psoriasis by Controlling Adenosine Triphosphate Expression in Keratinocytes and the Neuroimmune System.
Title: TRPV4 Regulates the Development of Psoriasis by Controlling Adenosine Triphosphate Expression in Keratinocytes and the Neuroimmune System.

Submit: New GeneRIF Correction See all GeneRIFs (279)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description	Tests
Avascular necrosis of femoral head, primary, 2 MedGen: C4479260 OMIM: 617383 GeneReviews: Autosomal Dominant TRPV4 Disorders	not available
Brachyrachia (short spine dysplasia) MedGen: C0432227 OMIM: 113500 GeneReviews: Autosomal Dominant TRPV4 Disorders	not available
Charcot-Marie-Tooth disease axonal type 2C MedGen: C1853710 OMIM: 606071 GeneReviews: Charcot-Marie-Tooth Hereditary Neuropathy Overview, Autosomal Dominant TRPV4 Disorders	not available
Familial digital arthropathy-brachydactyly MedGen: C1847406 OMIM: 606835 GeneReviews: Autosomal Dominant TRPV4 Disorders	not available
Metatropic dysplasia MedGen: C0265281 OMIM: 156530 GeneReviews: Autosomal Dominant TRPV4 Disorders	not available
Neuronopathy, distal hereditary motor, autosomal dominant 8 MedGen: C1838492 OMIM: 600175 GeneReviews: Autosomal Dominant TRPV4 Disorders	not available
Parastremmatic dwarfism MedGen: C1868616 OMIM: 168400 GeneReviews: Autosomal Dominant TRPV4 Disorders	not available
Scapuloperoneal spinal muscular atrophy MedGen: C0751335 OMIM: 181405 GeneReviews: Autosomal Dominant TRPV4 Disorders	not available
Sodium serum level quantitative trait locus 1 MedGen: C3150755 OMIM: 613508 GeneReviews: Not available	not available
Spondyloepimetaphyseal dysplasia, Maroteaux type MedGen: C3159322 OMIM: 184095 GeneReviews: Autosomal Dominant TRPV4 Disorders	not available
Spondylometaphyseal dysplasia, Kozlowski type MedGen: C0265280 OMIM: 184252 GeneReviews: Autosomal Dominant TRPV4 Disorders, Type II Collagen Disorders Overview	not available

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D12S105 (e-PCR), detects polymorphism
- UniSTS:81166

D12S1329 (e-PCR)
- UniSTS:32813

RH102999 (e-PCR)
- UniSTS:97333

Trpv4 (e-PCR), detects polymorphism
- UniSTS:531257

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables SH2 domain binding	ISS Inferred from Sequence or Structural Similarity more info
enables actin binding	ISS Inferred from Sequence or Structural Similarity more info
enables actin filament binding	ISS Inferred from Sequence or Structural Similarity more info
enables alpha-tubulin binding	ISS Inferred from Sequence or Structural Similarity more info
enables beta-tubulin binding	ISS Inferred from Sequence or Structural Similarity more info
enables calcium channel activity	IBA Inferred from Biological aspect of Ancestor more info
enables calcium channel activity	IDA Inferred from Direct Assay more info	PubMed
enables calcium channel activity	TAS Traceable Author Statement more info
enables calmodulin binding	IMP Inferred from Mutant Phenotype more info	PubMed
enables identical protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables lipid binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables microtubule binding	ISS Inferred from Sequence or Structural Similarity more info
enables monoatomic cation channel activity	IDA Inferred from Direct Assay more info	PubMed
enables osmosensor activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein kinase C binding	ISS Inferred from Sequence or Structural Similarity more info
enables protein kinase binding	IPI Inferred from Physical Interaction more info	PubMed
enables stretch-activated, monoatomic cation-selective, calcium channel activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in actin cytoskeleton organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in actin filament organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in actin filament organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in blood vessel endothelial cell delamination	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in calcium ion import	ISS Inferred from Sequence or Structural Similarity more info
involved_in calcium ion import across plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in calcium ion import into cytosol	IDA Inferred from Direct Assay more info	PubMed
involved_in calcium ion transmembrane transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in calcium ion transmembrane transport	TAS Traceable Author Statement more info
involved_in calcium ion transport	IDA Inferred from Direct Assay more info	PubMed
involved_in calcium ion transport	NAS Non-traceable Author Statement more info	PubMed
involved_in cartilage development involved in endochondral bone morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cell volume homeostasis	TAS Traceable Author Statement more info	PubMed
involved_in cell-cell junction assembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in cellular hypotonic response	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cellular hypotonic response	ISS Inferred from Sequence or Structural Similarity more info
involved_in cellular hypotonic salinity response	IEA Inferred from Electronic Annotation more info
involved_in cellular response to heat	ISS Inferred from Sequence or Structural Similarity more info
involved_in cellular response to osmotic stress	ISS Inferred from Sequence or Structural Similarity more info
involved_in cortical microtubule organization	ISS Inferred from Sequence or Structural Similarity more info
involved_in diet induced thermogenesis	IEA Inferred from Electronic Annotation more info
involved_in glucose homeostasis	IEA Inferred from Electronic Annotation more info
involved_in hyperosmotic salinity response	IEA Inferred from Electronic Annotation more info
involved_in intracellular calcium ion homeostasis	IDA Inferred from Direct Assay more info	PubMed
involved_in microtubule polymerization	ISS Inferred from Sequence or Structural Similarity more info
involved_in multicellular organismal-level water homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of brown fat cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of neuron projection development	ISS Inferred from Sequence or Structural Similarity more info
involved_in negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
involved_in osmosensory signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in osmosensory signaling pathway	ISS Inferred from Sequence or Structural Similarity more info
involved_in osmosensory signaling pathway	TAS Traceable Author Statement more info	PubMed
involved_in positive regulation of ERK1 and ERK2 cascade	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of JNK cascade	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of chemokine (C-C motif) ligand 5 production	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of chemokine (C-X-C motif) ligand 1 production	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of cytosolic calcium ion concentration	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of inflammatory response	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of interleukin-6 production	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of macrophage chemotaxis	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of macrophage inflammatory protein 1 alpha production	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of microtubule depolymerization	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of monocyte chemotactic protein-1 production	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of striated muscle contraction	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of vascular permeability	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of aerobic respiration	IEA Inferred from Electronic Annotation more info
involved_in regulation of response to osmotic stress	IEA Inferred from Electronic Annotation more info
involved_in response to hypoxia	IEA Inferred from Electronic Annotation more info
involved_in response to insulin	IEA Inferred from Electronic Annotation more info
involved_in response to mechanical stimulus	TAS Traceable Author Statement more info	PubMed
involved_in vasopressin secretion	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in adherens junction	ISS Inferred from Sequence or Structural Similarity more info
located_in apical plasma membrane	IEA Inferred from Electronic Annotation more info
located_in cell surface	IEA Inferred from Electronic Annotation more info
is_active_in cilium	IBA Inferred from Biological aspect of Ancestor more info
located_in cortical actin cytoskeleton	ISS Inferred from Sequence or Structural Similarity more info
colocalizes_with cytoplasmic microtubule	ISS Inferred from Sequence or Structural Similarity more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in filopodium	ISS Inferred from Sequence or Structural Similarity more info
located_in focal adhesion	ISS Inferred from Sequence or Structural Similarity more info
located_in growth cone	ISS Inferred from Sequence or Structural Similarity more info
located_in lamellipodium	ISS Inferred from Sequence or Structural Similarity more info
located_in membrane	NAS Non-traceable Author Statement more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info
located_in plasma membrane	TAS Traceable Author Statement more info
located_in ruffle membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: transient receptor potential cation channel subfamily V member 4

Names: OSM9-like transient receptor potential channel 4; osm-9-like TRP channel 4; osmosensitive transient receptor potential channel 4; transient receptor potential protein 12; vanilloid receptor-like channel 2; vanilloid receptor-related osmotically activated channel

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

NG_017090.1 RefSeqGene

Range

5001..55321

Download

GenBank, FASTA, Sequence Viewer (Graphics), LRG_372

mRNA and Protein(s)

NM_001177428.1 → NP_001170899.1 transient receptor potential cation channel subfamily V member 4 isoform e

See identical proteins and their annotated locations for NP_001170899.1

Status: REVIEWED

Description

Transcript Variant: This variant (5) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (c) is shorter, compared to isoform a.

Source sequence(s)

AB032427, AC007834, DA869138, DQ059644

Consensus CDS

CCDS53828.1

UniProtKB/Swiss-Prot

Q9HBA0

Related

ENSP00000442167.1, ENST00000541794.5

Conserved Domains (5) summary

cd00204
Location:236 → 343

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam00520
Location:511 → 683

Ion_trans; Ion transport protein

pfam09685
Location:502 → 548

DUF4870; Domain of unknown function (DUF4870)

pfam12796
Location:242 → 347

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:191 → 231

ANK; ANK repeat [structural motif]
NM_001177431.1 → NP_001170902.1 transient receptor potential cation channel subfamily V member 4 isoform d

See identical proteins and their annotated locations for NP_001170902.1

Status: REVIEWED

Description

Transcript Variant: This variant (4) lacks a segment in the 5' coding region coding region, compared to variant 1. The encoded isoform (d) is shorter, compared to isoform a.

Source sequence(s)

AB032427, AC007834, AF279673, DQ059645

Consensus CDS

CCDS53829.1

UniProtKB/Swiss-Prot

Q9HBA0

Related

ENSP00000444336.1, ENST00000536838.1

Conserved Domains (5) summary

cd00204
Location:204 → 356

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam00520
Location:524 → 696

Ion_trans; Ion transport protein

pfam09685
Location:515 → 561

DUF4870; Domain of unknown function (DUF4870)

pfam12796
Location:255 → 360

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:203 → 234

ANK; ANK repeat [structural motif]
NM_001177433.1 → NP_001170904.1 transient receptor potential cation channel subfamily V member 4 isoform c

See identical proteins and their annotated locations for NP_001170904.1

Status: REVIEWED

Description

Transcript Variant: This variant (3) lacks two in-frame exons in the coding region, compared to variant 1. The encoded isoform (c) is shorter, compared to isoform a.

Source sequence(s)

AB032427, BC143315, DQ059646

Consensus CDS

CCDS53827.1

UniProtKB/Swiss-Prot

Q9HBA0

Related

ENSP00000443611.1, ENST00000544971.5

Conserved Domains (4) summary

cd00204
Location:236 → 336

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

TIGR00870
Location:149 → 692

trp; transient-receptor-potential calcium channel protein

pfam09685
Location:442 → 488

DUF4870; Domain of unknown function (DUF4870)

sd00045
Location:191 → 231

ANK; ANK repeat [structural motif]
NM_021625.5 → NP_067638.3 transient receptor potential cation channel subfamily V member 4 isoform a

See identical proteins and their annotated locations for NP_067638.3

Status: REVIEWED

Description

Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).

Source sequence(s)

AC007834, AJ296305

Consensus CDS

CCDS9134.1

UniProtKB/Swiss-Prot

B7ZKQ6, Q17R79, Q2Y122, Q2Y123, Q2Y124, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBA0, Q9HBC0

Related

ENSP00000261740.2, ENST00000261740.7

Conserved Domains (5) summary

cd00204
Location:238 → 390

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam00520
Location:558 → 730

Ion_trans; Ion transport protein

pfam09685
Location:549 → 595

DUF4870; Domain of unknown function (DUF4870)

pfam12796
Location:289 → 394

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:237 → 268

ANK; ANK repeat [structural motif]
NM_147204.2 → NP_671737.1 transient receptor potential cation channel subfamily V member 4 isoform b

See identical proteins and their annotated locations for NP_671737.1

Status: REVIEWED

Description

Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1, resulting in an isoform (b) that lacks an internal segment compared to isoform a.

Source sequence(s)

AB032427, AB073669, AC007834, BC143315

Consensus CDS

CCDS9135.1

UniProtKB/Swiss-Prot

Q9HBA0

Related

ENSP00000442738.1, ENST00000537083.5

Conserved Domains (4) summary

cd00204
Location:238 → 383

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

TIGR00870
Location:149 → 739

trp; transient-receptor-potential calcium channel protein

pfam09685
Location:489 → 535

DUF4870; Domain of unknown function (DUF4870)

sd00045
Location:237 → 268

ANK; ANK repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000012.12 Reference GRCh38.p14 Primary Assembly

Range

109783087..109833398 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_047429295.1 → XP_047285251.1 transient receptor potential cation channel subfamily V member 4 isoform X9
XM_047429293.1 → XP_047285249.1 transient receptor potential cation channel subfamily V member 4 isoform X5
XM_047429294.1 → XP_047285250.1 transient receptor potential cation channel subfamily V member 4 isoform X7
XM_017019774.2 → XP_016875263.1 transient receptor potential cation channel subfamily V member 4 isoform X3

UniProtKB/Swiss-Prot

B7ZKQ6, Q17R79, Q2Y122, Q2Y123, Q2Y124, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBA0, Q9HBC0

Conserved Domains (5) summary

cd00204
Location:238 → 390

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam00520
Location:558 → 730

Ion_trans; Ion transport protein

pfam09685
Location:549 → 595

DUF4870; Domain of unknown function (DUF4870)

pfam12796
Location:289 → 394

Ank_2; Ankyrin repeats (3 copies)

sd00045
Location:237 → 268

ANK; ANK repeat [structural motif]
XM_011538633.3 → XP_011536935.2 transient receptor potential cation channel subfamily V member 4 isoform X6
XM_011538631.3 → XP_011536933.2 transient receptor potential cation channel subfamily V member 4 isoform X2
XM_011538632.3 → XP_011536934.2 transient receptor potential cation channel subfamily V member 4 isoform X4
XM_011538630.3 → XP_011536932.2 transient receptor potential cation channel subfamily V member 4 isoform X1
XM_011538634.3 → XP_011536936.2 transient receptor potential cation channel subfamily V member 4 isoform X8
XM_011538635.3 → XP_011536937.1 transient receptor potential cation channel subfamily V member 4 isoform X10

Conserved Domains (2) summary

TIGR00870
Location:200 → 682

trp; transient-receptor-potential calcium channel protein

sd00045
Location:288 → 319

ANK; ANK repeat [structural motif]
XM_047429296.1 → XP_047285252.1 transient receptor potential cation channel subfamily V member 4 isoform X11

UniProtKB/TrEMBL

F5H6Q4

Related

ENSP00000437449.1, ENST00000538125.5

Alternate T2T-CHM13v2.0

Genomic

NC_060936.1 Alternate T2T-CHM13v2.0

Range

109758559..109808862 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054372806.1 → XP_054228781.1 transient receptor potential cation channel subfamily V member 4 isoform X9
XM_054372802.1 → XP_054228777.1 transient receptor potential cation channel subfamily V member 4 isoform X5
XM_054372804.1 → XP_054228779.1 transient receptor potential cation channel subfamily V member 4 isoform X7
XM_054372800.1 → XP_054228775.1 transient receptor potential cation channel subfamily V member 4 isoform X3

UniProtKB/Swiss-Prot

B7ZKQ6, Q17R79, Q2Y122, Q2Y123, Q2Y124, Q86YZ6, Q8NDY7, Q8NG64, Q96Q92, Q96RS7, Q9HBA0, Q9HBC0
XM_054372803.1 → XP_054228778.1 transient receptor potential cation channel subfamily V member 4 isoform X6
XM_054372799.1 → XP_054228774.1 transient receptor potential cation channel subfamily V member 4 isoform X2
XM_054372801.1 → XP_054228776.1 transient receptor potential cation channel subfamily V member 4 isoform X4
XM_054372798.1 → XP_054228773.1 transient receptor potential cation channel subfamily V member 4 isoform X1
XM_054372805.1 → XP_054228780.1 transient receptor potential cation channel subfamily V member 4 isoform X8
XM_054372807.1 → XP_054228782.1 transient receptor potential cation channel subfamily V member 4 isoform X10
XM_054372808.1 → XP_054228783.1 transient receptor potential cation channel subfamily V member 4 isoform X11

UniProtKB/TrEMBL

F5H6Q4