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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_030334.1 RefSeqGene
- Range
-
4675..274474
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_006909.3 → NP_008840.1 ras-specific guanine nucleotide-releasing factor 2
See identical proteins and their annotated locations for NP_008840.1
Status: REVIEWED
- Source sequence(s)
-
AC026427, BC041953, BC136296, BU430075, BX502901, CR749239, DA219722, DA230428
- Consensus CDS
-
CCDS4052.1
- UniProtKB/Swiss-Prot
- B9EG89, O14827, Q9UK56
- UniProtKB/TrEMBL
- A0A2X0SFL3, D6RAS9
- Related
- ENSP00000265080.4, ENST00000265080.9
- Conserved Domains (6) summary
-
- smart00147
Location:998 → 1234
- RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
- smart00229
Location:901 → 972
- RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
- smart00233
Location:480 → 588
- PH; Pleckstrin homology domain
- smart00325
Location:247 → 428
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
- cd13261
Location:19 → 158
- PH_RasGRF1_2; Ras-specific guanine nucleotide-releasing factors 1 and 2 Pleckstrin homology (PH) domain
- pfam00618
Location:638 → 686
- RasGEF_N; RasGEF N-terminal motif
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000005.10 Reference GRCh38.p14 Primary Assembly
- Range
-
80960363..81230162
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_005248565.2 → XP_005248622.1 ras-specific guanine nucleotide-releasing factor 2 isoform X3
- UniProtKB/TrEMBL
-
D6RAS9
- Conserved Domains (6) summary
-
- smart00233
Location:480 → 588
- PH; Pleckstrin homology domain
- cd13261
Location:19 → 158
- PH_RasGRF1_2; Ras-specific guanine nucleotide-releasing factors 1 and 2 Pleckstrin homology (PH) domain
- pfam00169
Location:24 → 133
- PH; PH domain
- pfam00618
Location:638 → 686
- RasGEF_N; RasGEF N-terminal motif
- pfam00621
Location:247 → 428
- RhoGEF; RhoGEF domain
- cl02520
Location:901 → 931
- REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
-
XM_017009683.2 → XP_016865172.1 ras-specific guanine nucleotide-releasing factor 2 isoform X4
-
XM_047417464.1 → XP_047273420.1 ras-specific guanine nucleotide-releasing factor 2 isoform X1
- UniProtKB/TrEMBL
-
D6RAS9
-
XM_047417463.1 → XP_047273419.1 ras-specific guanine nucleotide-releasing factor 2 isoform X1
- UniProtKB/TrEMBL
-
D6RAS9
-
XM_047417466.1 → XP_047273422.1 ras-specific guanine nucleotide-releasing factor 2 isoform X2
- UniProtKB/TrEMBL
-
D6RAS9
-
XM_047417465.1 → XP_047273421.1 ras-specific guanine nucleotide-releasing factor 2 isoform X2
- UniProtKB/TrEMBL
-
D6RAS9
Alternate T2T-CHM13v2.0
Genomic
-
NC_060929.1 Alternate T2T-CHM13v2.0
- Range
-
81444995..81714744
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054353040.1 → XP_054209015.1 ras-specific guanine nucleotide-releasing factor 2 isoform X3
- UniProtKB/TrEMBL
-
D6RAS9
-
XM_054353041.1 → XP_054209016.1 ras-specific guanine nucleotide-releasing factor 2 isoform X4
-
XM_054353037.1 → XP_054209012.1 ras-specific guanine nucleotide-releasing factor 2 isoform X1
- UniProtKB/TrEMBL
-
D6RAS9
-
XM_054353036.1 → XP_054209011.1 ras-specific guanine nucleotide-releasing factor 2 isoform X1
- UniProtKB/TrEMBL
-
D6RAS9
-
XM_054353039.1 → XP_054209014.1 ras-specific guanine nucleotide-releasing factor 2 isoform X2
- UniProtKB/TrEMBL
-
D6RAS9
-
XM_054353038.1 → XP_054209013.1 ras-specific guanine nucleotide-releasing factor 2 isoform X2
- UniProtKB/TrEMBL
-
D6RAS9