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    LCN15 lipocalin 15 [ Homo sapiens (human) ]

    Gene ID: 389812, updated on 9-Dec-2024

    Summary

    Official Symbol
    LCN15provided by HGNC
    Official Full Name
    lipocalin 15provided by HGNC
    Primary source
    HGNC:HGNC:33777
    See related
    Ensembl:ENSG00000177984 AllianceGenome:HGNC:33777
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PRO6093; UNQ2541
    Summary
    Predicted to enable small molecule binding activity. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in duodenum (RPKM 4.8), colon (RPKM 2.3) and 2 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See LCN15 in Genome Data Viewer
    Location:
    9q34.3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (136759634..136764518, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (148992812..148997698, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (139654086..139658970, complement)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100128593 Neighboring gene lipocalin 6 Neighboring gene microRNA 6722 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29324 Neighboring gene lipocalin 8 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139657693-139658340 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29325 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 29326 Neighboring gene uncharacterized LOC107987143 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:139665256-139665756 Neighboring gene Sharpr-MPRA regulatory region 7361 Neighboring gene ATPase H+ transporting V1 subunit G1 pseudogene 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables small molecule binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    lipocalin-15
    Names
    MSFL2541
    NP_976222.1
    XP_011516974.1
    XP_054218929.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_203347.2NP_976222.1  lipocalin-15 precursor

      See identical proteins and their annotated locations for NP_976222.1

      Status: VALIDATED

      Source sequence(s)
      AL355987, AY358618
      Consensus CDS
      CCDS7006.1
      UniProtKB/Swiss-Prot
      Q6UWW0
      Related
      ENSP00000313833.5, ENST00000316144.6
      Conserved Domains (1) summary
      pfam00061
      Location:34174
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

      Range
      136759634..136764518 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011518672.2XP_011516974.1  lipocalin-15 isoform X1

      Conserved Domains (1) summary
      pfam00061
      Location:6131
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060933.1 Alternate T2T-CHM13v2.0

      Range
      148992812..148997698 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054362954.1XP_054218929.1  lipocalin-15 isoform X1