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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029903.2 RefSeqGene
- Range
-
12132..159024
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001394154.1 → NP_001381083.1 regulator of G-protein signaling 12 isoform 1
Status: REVIEWED
- Source sequence(s)
-
AL590235, AL645949
- Consensus CDS
-
CCDS3366.1
- UniProtKB/Swiss-Prot
- B1AQ30, B1AQ31, B1AQ32, B7Z764, E7EMN9, O14922, O14923, O14924, O43510, O75338, Q147X0, Q8WX95
- Related
- ENSP00000338509.4, ENST00000336727.8
- Conserved Domains (9) summary
-
- cd08742
Location:716 → 830
- RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
- smart00390
Location:1188 → 1209
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- cd00992
Location:20 → 96
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13162
Location:228 → 359
- PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
- cd17136
Location:962 → 1031
- RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
- pfam16611
Location:1106 → 1180
- RGS12_us2; Unstructured region between RBD and GoLoco
- pfam16612
Location:1239 → 1376
- RGS12_usC; C-terminal unstructured region of RGS12
- pfam16613
Location:836 → 949
- RGS12_us1; Unstructured region of RGS12
- cl28922
Location:1032 → 1104
- Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
-
NM_001394155.1 → NP_001381084.1 regulator of G-protein signaling 12 isoform 1
Status: REVIEWED
- Source sequence(s)
-
AL590235, AL645949
- Consensus CDS
-
CCDS3366.1
- UniProtKB/Swiss-Prot
- B1AQ30, B1AQ31, B1AQ32, B7Z764, E7EMN9, O14922, O14923, O14924, O43510, O75338, Q147X0, Q8WX95
- Conserved Domains (9) summary
-
- cd08742
Location:716 → 830
- RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
- smart00390
Location:1188 → 1209
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- cd00992
Location:20 → 96
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13162
Location:228 → 359
- PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
- cd17136
Location:962 → 1031
- RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
- pfam16611
Location:1106 → 1180
- RGS12_us2; Unstructured region between RBD and GoLoco
- pfam16612
Location:1239 → 1376
- RGS12_usC; C-terminal unstructured region of RGS12
- pfam16613
Location:836 → 949
- RGS12_us1; Unstructured region of RGS12
- cl28922
Location:1032 → 1104
- Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
-
NM_001394156.1 → NP_001381085.1 regulator of G-protein signaling 12 isoform 2
Status: REVIEWED
- Source sequence(s)
-
AL590235, AL645949
- Consensus CDS
-
CCDS3367.1
- Related
- ENSP00000372238.3, ENST00000382788.7
- Conserved Domains (9) summary
-
- cd08742
Location:716 → 830
- RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
- smart00390
Location:1188 → 1209
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- cd00992
Location:20 → 96
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13162
Location:228 → 359
- PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
- cd17136
Location:962 → 1031
- RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
- pfam16611
Location:1106 → 1180
- RGS12_us2; Unstructured region between RBD and GoLoco
- pfam16612
Location:1239 → 1376
- RGS12_usC; C-terminal unstructured region of RGS12
- pfam16613
Location:836 → 949
- RGS12_us1; Unstructured region of RGS12
- cl28922
Location:1032 → 1104
- Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
-
NM_001394157.1 → NP_001381086.1 regulator of G-protein signaling 12 isoform 4
Status: REVIEWED
- Source sequence(s)
-
AL590235, AL645949
- UniProtKB/TrEMBL
-
Q56A82
- Conserved Domains (5) summary
-
- cd08742
Location:716 → 830
- RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
- cd00992
Location:20 → 96
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13162
Location:228 → 359
- PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
- cd17136
Location:962 → 1031
- RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
- cl28922
Location:1032 → 1104
- Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
-
NM_001394158.1 → NP_001381087.1 regulator of G-protein signaling 12 isoform 5
Status: REVIEWED
- Source sequence(s)
-
AL590235, AL645949
- UniProtKB/TrEMBL
-
Q56A82
- Conserved Domains (7) summary
-
- cd08742
Location:716 → 830
- RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
- cd00992
Location:20 → 96
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13162
Location:228 → 359
- PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
- cd17136
Location:962 → 1031
- RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
- pfam16611
Location:1106 → 1137
- RGS12_us2; Unstructured region between RBD and GoLoco
- pfam16613
Location:836 → 949
- RGS12_us1; Unstructured region of RGS12
- cl28922
Location:1032 → 1104
- Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
-
NM_001394159.1 → NP_001381088.1 regulator of G-protein signaling 12 isoform 6
Status: REVIEWED
- Source sequence(s)
-
AL645949
- Conserved Domains (4) summary
-
- PHA03247
Location:452 → 814
- PHA03247; large tegument protein UL36; Provisional
- cd00992
Location:20 → 96
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13162
Location:228 → 359
- PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
- cd21577
Location:738 → 824
- KLF3_N; N-terminal domain of Kruppel-like factor 3
-
NM_001394161.1 → NP_001381090.1 regulator of G-protein signaling 12 isoform 7
Status: REVIEWED
- Source sequence(s)
-
AL590235, AL645949
- UniProtKB/TrEMBL
-
Q506M0
- Conserved Domains (7) summary
-
- smart00390
Location:387 → 408
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- cd17136
Location:161 → 230
- RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
- pfam16611
Location:305 → 379
- RGS12_us2; Unstructured region between RBD and GoLoco
- pfam16612
Location:438 → 575
- RGS12_usC; C-terminal unstructured region of RGS12
- pfam16613
Location:35 → 148
- RGS12_us1; Unstructured region of RGS12
- cl02565
Location:1 → 29
- RGS; Regulator of G protein signaling (RGS) domain superfamily
- cl28922
Location:231 → 303
- Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
-
NM_001394162.1 → NP_001381091.1 regulator of G-protein signaling 12 isoform 7
Status: REVIEWED
- Source sequence(s)
-
AL590235, AL645949
- UniProtKB/TrEMBL
-
Q506M0
- Conserved Domains (7) summary
-
- smart00390
Location:387 → 408
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- cd17136
Location:161 → 230
- RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
- pfam16611
Location:305 → 379
- RGS12_us2; Unstructured region between RBD and GoLoco
- pfam16612
Location:438 → 575
- RGS12_usC; C-terminal unstructured region of RGS12
- pfam16613
Location:35 → 148
- RGS12_us1; Unstructured region of RGS12
- cl02565
Location:1 → 29
- RGS; Regulator of G protein signaling (RGS) domain superfamily
- cl28922
Location:231 → 303
- Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
-
NM_001394163.1 → NP_001381092.1 regulator of G-protein signaling 12 isoform 7
Status: REVIEWED
- Source sequence(s)
-
AL590235, AL645949
- UniProtKB/TrEMBL
-
Q506M0
- Conserved Domains (7) summary
-
- smart00390
Location:387 → 408
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- cd17136
Location:161 → 230
- RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
- pfam16611
Location:305 → 379
- RGS12_us2; Unstructured region between RBD and GoLoco
- pfam16612
Location:438 → 575
- RGS12_usC; C-terminal unstructured region of RGS12
- pfam16613
Location:35 → 148
- RGS12_us1; Unstructured region of RGS12
- cl02565
Location:1 → 29
- RGS; Regulator of G protein signaling (RGS) domain superfamily
- cl28922
Location:231 → 303
- Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
-
NM_002926.5 → NP_002917.1 regulator of G-protein signaling 12 isoform 2
See identical proteins and their annotated locations for NP_002917.1
Status: REVIEWED
- Source sequence(s)
-
AL590235, AL645949
- Consensus CDS
-
CCDS3367.1
- UniProtKB/Swiss-Prot
-
O14924
- Conserved Domains (9) summary
-
- cd08742
Location:716 → 830
- RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
- smart00390
Location:1188 → 1209
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- cd00992
Location:20 → 96
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13162
Location:228 → 359
- PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
- cd17136
Location:962 → 1031
- RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
- pfam16611
Location:1106 → 1180
- RGS12_us2; Unstructured region between RBD and GoLoco
- pfam16612
Location:1239 → 1376
- RGS12_usC; C-terminal unstructured region of RGS12
- pfam16613
Location:836 → 949
- RGS12_us1; Unstructured region of RGS12
- cl28922
Location:1032 → 1104
- Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
-
NM_198227.2 → NP_937870.1 regulator of G-protein signaling 12 isoform 3
See identical proteins and their annotated locations for NP_937870.1
Status: REVIEWED
- Source sequence(s)
-
AF030109, AF030112, BM984992, CB242608
- Consensus CDS
-
CCDS3368.1
- UniProtKB/TrEMBL
-
Q506M0
- Related
- ENSP00000342133.4, ENST00000338806.4
- Conserved Domains (7) summary
-
- smart00455
Location:387 → 456
- RBD; Raf-like Ras-binding domain
- cd01817
Location:315 → 387
- RGS12_RBD; Ubiquitin domain of RGS12 and RGS14
- cd08742
Location:68 → 182
- RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
- pfam02188
Location:540 → 561
- GoLoco; GoLoco motif
- pfam16611
Location:458 → 528
- RGS12_us2; Unstructured region between RBD and GoLoco
- pfam16612
Location:606 → 726
- RGS12_usC; C-terminal unstructured region of RGS12
- pfam16613
Location:188 → 285
- RGS12_us1; Unstructured region of RGS12
-
NM_198229.3 → NP_937872.1 regulator of G-protein signaling 12 isoform 1
See identical proteins and their annotated locations for NP_937872.1
Status: REVIEWED
- Source sequence(s)
-
AL590235, AL645949
- Consensus CDS
-
CCDS3366.1
- UniProtKB/Swiss-Prot
- B1AQ30, B1AQ31, B1AQ32, B7Z764, E7EMN9, O14922, O14923, O14924, O43510, O75338, Q147X0, Q8WX95
- Related
- ENSP00000339381.5, ENST00000344733.9
- Conserved Domains (9) summary
-
- cd08742
Location:716 → 830
- RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
- smart00390
Location:1188 → 1209
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- cd00992
Location:20 → 96
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13162
Location:228 → 359
- PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
- cd17136
Location:962 → 1031
- RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
- pfam16611
Location:1106 → 1180
- RGS12_us2; Unstructured region between RBD and GoLoco
- pfam16612
Location:1239 → 1376
- RGS12_usC; C-terminal unstructured region of RGS12
- pfam16613
Location:836 → 949
- RGS12_us1; Unstructured region of RGS12
- cl28922
Location:1032 → 1104
- Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000004.12 Reference GRCh38.p14 Primary Assembly
- Range
-
3285891..3439913
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011513543.3 → XP_011511845.1 regulator of G-protein signaling 12 isoform X5
See identical proteins and their annotated locations for XP_011511845.1
- UniProtKB/TrEMBL
-
Q506M0
- Conserved Domains (7) summary
-
- smart00390
Location:387 → 408
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- cd17136
Location:161 → 230
- RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
- pfam16611
Location:305 → 379
- RGS12_us2; Unstructured region between RBD and GoLoco
- pfam16612
Location:438 → 575
- RGS12_usC; C-terminal unstructured region of RGS12
- pfam16613
Location:35 → 148
- RGS12_us1; Unstructured region of RGS12
- cl02565
Location:1 → 29
- RGS; Regulator of G protein signaling (RGS) domain superfamily
- cl28922
Location:231 → 303
- Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
-
XM_047416060.1 → XP_047272016.1 regulator of G-protein signaling 12 isoform X7
- UniProtKB/TrEMBL
-
B3KVS7
-
XM_017008529.3 → XP_016864018.1 regulator of G-protein signaling 12 isoform X1
- UniProtKB/Swiss-Prot
- B1AQ30, B1AQ31, B1AQ32, B7Z764, E7EMN9, O14922, O14923, O14924, O43510, O75338, Q147X0, Q8WX95
- Conserved Domains (9) summary
-
- cd08742
Location:716 → 830
- RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
- smart00390
Location:1188 → 1209
- GoLoco; LGN motif, putative GEFs specific for G-alpha GTPases
- cd00992
Location:20 → 96
- PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
- cd13162
Location:228 → 359
- PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
- cd17136
Location:962 → 1031
- RBD1_RGS12; Ras-binding domain (RBD) 1 of regulator of G protein signaling 12 (RGS12)
- pfam16611
Location:1106 → 1180
- RGS12_us2; Unstructured region between RBD and GoLoco
- pfam16612
Location:1239 → 1376
- RGS12_usC; C-terminal unstructured region of RGS12
- pfam16613
Location:836 → 949
- RGS12_us1; Unstructured region of RGS12
- cl28922
Location:1032 → 1104
- Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
-
XM_047416055.1 → XP_047272011.1 regulator of G-protein signaling 12 isoform X2
- UniProtKB/TrEMBL
-
Q56A82
-
XM_047416056.1 → XP_047272012.1 regulator of G-protein signaling 12 isoform X3
- UniProtKB/TrEMBL
-
Q56A82
-
XM_047416057.1 → XP_047272013.1 regulator of G-protein signaling 12 isoform X4
-
XM_017008534.2 → XP_016864023.1 regulator of G-protein signaling 12 isoform X6
-
XM_047416058.1 → XP_047272014.1 regulator of G-protein signaling 12 isoform X5
- UniProtKB/TrEMBL
-
Q506M0
-
XM_047416059.1 → XP_047272015.1 regulator of G-protein signaling 12 isoform X5
- UniProtKB/TrEMBL
-
Q506M0
Alternate T2T-CHM13v2.0
Genomic
-
NC_060928.1 Alternate T2T-CHM13v2.0
- Range
-
3284640..3439697
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054350686.1 → XP_054206661.1 regulator of G-protein signaling 12 isoform X5
- UniProtKB/TrEMBL
-
Q506M0
-
XM_054350688.1 → XP_054206663.1 regulator of G-protein signaling 12 isoform X7
- UniProtKB/TrEMBL
-
B3KVS7
-
XM_054350682.1 → XP_054206657.1 regulator of G-protein signaling 12 isoform X1
- UniProtKB/Swiss-Prot
- B1AQ30, B1AQ31, B1AQ32, B7Z764, E7EMN9, O14922, O14923, O14924, O43510, O75338, Q147X0, Q8WX95
-
XM_054350683.1 → XP_054206658.1 regulator of G-protein signaling 12 isoform X2
- UniProtKB/TrEMBL
-
Q56A82
-
XM_054350685.1 → XP_054206660.1 regulator of G-protein signaling 12 isoform X3
- UniProtKB/TrEMBL
-
Q56A82
-
XM_054350684.1 → XP_054206659.1 regulator of G-protein signaling 12 isoform X8
-
XM_054350687.1 → XP_054206662.1 regulator of G-protein signaling 12 isoform X6
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_198230.1: Suppressed sequence
- Description
- NM_198230.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
-
NM_198430.1: Suppressed sequence
- Description
- NM_198430.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
-
NM_198432.1: Suppressed sequence
- Description
- NM_198432.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
-
NM_198587.1: Suppressed sequence
- Description
- NM_198587.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.