U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    UTP11 UTP11 small subunit processome component [ Homo sapiens (human) ]

    Gene ID: 51118, updated on 27-Nov-2024

    Summary

    Official Symbol
    UTP11provided by HGNC
    Official Full Name
    UTP11 small subunit processome componentprovided by HGNC
    Primary source
    HGNC:HGNC:24329
    See related
    Ensembl:ENSG00000183520 MIM:609440; AllianceGenome:HGNC:24329
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CGI94; CGI-94; UTP11L
    Summary
    Enables RNA binding activity. Involved in nervous system development; positive regulation of apoptotic process; and ribosomal small subunit biogenesis. Located in cytoplasm; extracellular space; and nucleolus. Part of small-subunit processome. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in adrenal (RPKM 11.3), esophagus (RPKM 10.1) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See UTP11 in Genome Data Viewer
    Location:
    1p34.3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (38012734..38024820)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (37879913..37892000)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (38478406..38490492)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 8264 Neighboring gene RNA, U6 small nuclear 510, pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:38463160-38464081 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:38465171-38465958 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:38465959-38466746 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:38469196-38470004 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 684 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 685 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 782 Neighboring gene four and a half LIM domains 3 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:38491775-38492274 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:38492441-38492993 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:38492994-38493545 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 783 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 784 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 785 Neighboring gene Sharpr-MPRA regulatory region 3132 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:38512768-38513268 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:38513269-38513769 Neighboring gene MIR3659 host gene Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 687 Neighboring gene POU class 3 homeobox 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 786 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 787 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:38537009-38537508 Neighboring gene microRNA 3659

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables RNA binding HDA PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal small subunit biogenesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of small-subunit processome IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    probable U3 small nucleolar RNA-associated protein 11
    Names
    U3 snoRNA-associated protein 11
    UTP11, small subunit processome component homolog
    UTP11-like protein
    UTP11-like, U3 small nucleolar ribonucleoprotein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016037.4NP_057121.2  probable U3 small nucleolar RNA-associated protein 11

      See identical proteins and their annotated locations for NP_057121.2

      Status: VALIDATED

      Source sequence(s)
      AF151852, BI493106, BU620078, BU940926, CX163866
      Consensus CDS
      CCDS429.1
      UniProtKB/Swiss-Prot
      A8K785, B4DJC6, D3DPT7, Q5VT93, Q9BS98, Q9NS31, Q9Y3A2
      Related
      ENSP00000362105.4, ENST00000373014.5
      Conserved Domains (1) summary
      pfam03998
      Location:13253
      Utp11; Utp11 protein

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      38012734..38024820
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011541555.3XP_011539857.1  probable U3 small nucleolar RNA-associated protein 11 isoform X1

      See identical proteins and their annotated locations for XP_011539857.1

      Conserved Domains (1) summary
      pfam03998
      Location:1184
      Utp11; Utp11 protein

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      37879913..37892000
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054336893.1XP_054192868.1  probable U3 small nucleolar RNA-associated protein 11 isoform X1