U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FAM210B family with sequence similarity 210 member B [ Homo sapiens (human) ]

    Gene ID: 116151, updated on 28-Oct-2024

    Summary

    Official Symbol
    FAM210Bprovided by HGNC
    Official Full Name
    family with sequence similarity 210 member Bprovided by HGNC
    Primary source
    HGNC:HGNC:16102
    See related
    Ensembl:ENSG00000124098 MIM:618722; AllianceGenome:HGNC:16102
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    5A3; C20orf108; dJ1167H4.1
    Summary
    Involved in cellular response to estradiol stimulus and positive regulation of erythrocyte differentiation. Located in mitochondrial outer membrane. [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Ubiquitous expression in ovary (RPKM 51.5), adrenal (RPKM 50.1) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See FAM210B in Genome Data Viewer
    Location:
    20q13.2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (56358974..56368663)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (58136516..58146109)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (54934030..54943719)

    Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene RNA, 5S ribosomal pseudogene 487 Neighboring gene NANOG hESC enhancer GRCh37_chr20:54792881-54793405 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13056 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr20:54834703-54835902 Neighboring gene melanocortin 3 receptor Neighboring gene Sharpr-MPRA regulatory region 10041 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13057 Neighboring gene ReSE screen-validated silencer GRCh37_chr20:54937273-54937462 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:54938029-54938529 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr20:54961142-54962341 Neighboring gene aurora kinase A Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18142 Neighboring gene cleavage stimulation factor subunit 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    protein FAM210B, mitochondrial
    Names
    transmembrane protein C20orf108

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_080821.3NP_543011.2  protein FAM210B, mitochondrial

      See identical proteins and their annotated locations for NP_543011.2

      Status: VALIDATED

      Source sequence(s)
      AK075565, AL133555, DB500825
      Consensus CDS
      CCDS13450.1
      UniProtKB/Swiss-Prot
      B2RBQ9, E1P5Y7, Q8WVN2, Q96KR6, Q9BYL6, Q9H418
      Related
      ENSP00000360437.3, ENST00000371384.4
      Conserved Domains (1) summary
      pfam06916
      Location:87174
      DUF1279; Protein of unknown function (DUF1279)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

      Range
      56358974..56368663
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060944.1 Alternate T2T-CHM13v2.0

      Range
      58136516..58146109
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)