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    TMUB2 transmembrane and ubiquitin like domain containing 2 [ Homo sapiens (human) ]

    Gene ID: 79089, updated on 2-Nov-2024

    Summary

    Official Symbol
    TMUB2provided by HGNC
    Official Full Name
    transmembrane and ubiquitin like domain containing 2provided by HGNC
    Primary source
    HGNC:HGNC:28459
    See related
    Ensembl:ENSG00000168591 AllianceGenome:HGNC:28459
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    FP2653
    Summary
    Predicted to be involved in ERAD pathway. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in testis (RPKM 16.4), spleen (RPKM 14.8) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See TMUB2 in Genome Data Viewer
    Location:
    17q21.31
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (44186972..44191929)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (45040074..45045031)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (42264340..42269297)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8576 Neighboring gene Sharpr-MPRA regulatory region 5 Neighboring gene homologous recombination factor with OB-fold Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12254 Neighboring gene ankyrin repeat and SOCS box containing 16 Neighboring gene ASB16 antisense RNA 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:42263664-42264198 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:42274223-42275146 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:42275147-42276069 Neighboring gene ataxin 7 like 3 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:42276274-42276829 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:42277555-42278093 Neighboring gene ATXN7L3 antisense RNA 1 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:42278094-42278631 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:42284331-42284831 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr17:42285473-42286672 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8579 Neighboring gene Sharpr-MPRA regulatory region 7848 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8581 Neighboring gene microRNA 6782 Neighboring gene upstream binding transcription factor Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8582 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:42296769-42296933 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8584 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 8585 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:42299194-42299798 Neighboring gene SHC adaptor protein 1 pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC3123

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in ERAD pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transmembrane and ubiquitin-like domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076674.3NP_001070142.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform b

      See identical proteins and their annotated locations for NP_001070142.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) includes an alternate exon with an upstream start codon, compared to variant 1. The resulting protein (isoform b) has a longer N-terminus, compared to isoform a.
      Source sequence(s)
      AC004596, AL533563, AL538440, BI906577, BM999307
      Consensus CDS
      CCDS54134.1
      UniProtKB/Swiss-Prot
      B3KU81, Q71RG4, Q8NDI2, Q9BPZ5, Q9HAG3
      UniProtKB/TrEMBL
      B4DFQ1
      Related
      ENSP00000444565.1, ENST00000538716.7
      Conserved Domains (1) summary
      pfam00240
      Location:176245
      ubiquitin; Ubiquitin family
    2. NM_001330235.2NP_001317164.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform c

      Status: VALIDATED

      Source sequence(s)
      AK294198, BC004306, BM999307
      Consensus CDS
      CCDS82137.1
      UniProtKB/TrEMBL
      B4DFQ1, E7ESS3
      Related
      ENSP00000413127.2, ENST00000446571.7
      Conserved Domains (1) summary
      pfam00240
      Location:119188
      ubiquitin; Ubiquitin family
    3. NM_001353173.2NP_001340102.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC004596
      Consensus CDS
      CCDS11479.1
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      cd17132
      Location:153223
      Ubl_TMUB2; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2)
    4. NM_001353174.2NP_001340103.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform c

      Status: VALIDATED

      Source sequence(s)
      AC004596
      Consensus CDS
      CCDS82137.1
      UniProtKB/TrEMBL
      B4DFQ1, E7ESS3
      Conserved Domains (1) summary
      pfam00240
      Location:119188
      ubiquitin; Ubiquitin family
    5. NM_001353175.2NP_001340104.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC004596
      Consensus CDS
      CCDS11479.1
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      cd17132
      Location:153223
      Ubl_TMUB2; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2)
    6. NM_001353176.2NP_001340105.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC004596
      Consensus CDS
      CCDS11479.1
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      cd17132
      Location:153223
      Ubl_TMUB2; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2)
    7. NM_001353177.2NP_001340106.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC004596
      Consensus CDS
      CCDS54134.1
      UniProtKB/Swiss-Prot
      B3KU81, Q71RG4, Q8NDI2, Q9BPZ5, Q9HAG3
      UniProtKB/TrEMBL
      B4DFQ1
      Related
      ENSP00000466971.1, ENST00000587989.1
      Conserved Domains (1) summary
      pfam00240
      Location:176245
      ubiquitin; Ubiquitin family
    8. NM_001353178.2NP_001340107.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC004596
      Consensus CDS
      CCDS11479.1
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      cd17132
      Location:153223
      Ubl_TMUB2; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2)
    9. NM_001353180.2NP_001340109.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform f

      Status: VALIDATED

      Source sequence(s)
      AC004596
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      cd17132
      Location:164234
      Ubl_TMUB2; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2)
    10. NM_001353181.2NP_001340110.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC004596
      Consensus CDS
      CCDS54134.1
      UniProtKB/Swiss-Prot
      B3KU81, Q71RG4, Q8NDI2, Q9BPZ5, Q9HAG3
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      pfam00240
      Location:176245
      ubiquitin; Ubiquitin family
    11. NM_001353182.2NP_001340111.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC004596
      Consensus CDS
      CCDS11479.1
      UniProtKB/TrEMBL
      B4DFQ1
      Related
      ENSP00000467364.1, ENST00000589785.1
      Conserved Domains (1) summary
      cd17132
      Location:153223
      Ubl_TMUB2; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2)
    12. NM_001353183.2NP_001340112.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC004596
      Consensus CDS
      CCDS11479.1
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      cd17132
      Location:153223
      Ubl_TMUB2; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2)
    13. NM_001353184.2NP_001340113.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC004596
      Consensus CDS
      CCDS54134.1
      UniProtKB/Swiss-Prot
      B3KU81, Q71RG4, Q8NDI2, Q9BPZ5, Q9HAG3
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      pfam00240
      Location:176245
      ubiquitin; Ubiquitin family
    14. NM_001353185.2NP_001340114.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform e

      Status: VALIDATED

      Source sequence(s)
      AC004596
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      pfam00240
      Location:130199
      ubiquitin; Ubiquitin family
    15. NM_001353186.2NP_001340115.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform d

      Status: VALIDATED

      Source sequence(s)
      AC004596
    16. NM_001353187.2NP_001340116.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform e

      Status: VALIDATED

      Source sequence(s)
      AC004596
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      pfam00240
      Location:130199
      ubiquitin; Ubiquitin family
    17. NM_001353188.2NP_001340117.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC004596
      Consensus CDS
      CCDS11479.1
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      cd17132
      Location:153223
      Ubl_TMUB2; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2)
    18. NM_001353189.2NP_001340118.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform f

      Status: VALIDATED

      Source sequence(s)
      AC004596
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      cd17132
      Location:164234
      Ubl_TMUB2; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2)
    19. NM_001353190.2NP_001340119.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC004596
      Consensus CDS
      CCDS11479.1
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      cd17132
      Location:153223
      Ubl_TMUB2; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2)
    20. NM_001353191.2NP_001340120.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC004596
      Consensus CDS
      CCDS11479.1
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      cd17132
      Location:153223
      Ubl_TMUB2; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2)
    21. NM_024107.4NP_077012.2  transmembrane and ubiquitin-like domain-containing protein 2 isoform a

      See identical proteins and their annotated locations for NP_077012.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shortest transcript. Variants 1 and 2 encode the same isoform (a).
      Source sequence(s)
      AC004596, BC063489, BI906577, BM999307
      Consensus CDS
      CCDS11479.1
      UniProtKB/TrEMBL
      B4DFQ1
      Related
      ENSP00000350672.3, ENST00000357984.7
      Conserved Domains (1) summary
      cd17132
      Location:153223
      Ubl_TMUB2; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2)
    22. NM_177441.4NP_803190.2  transmembrane and ubiquitin-like domain-containing protein 2 isoform a

      See identical proteins and their annotated locations for NP_803190.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (a).
      Source sequence(s)
      AC004596, AL833899, BM999307, HY071246
      Consensus CDS
      CCDS11479.1
      UniProtKB/TrEMBL
      B4DFQ1
      Related
      ENSP00000313214.5, ENST00000319511.6
      Conserved Domains (1) summary
      cd17132
      Location:153223
      Ubl_TMUB2; ubiquitin-like (Ubl) domain found in transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2)

    RNA

    1. NR_148386.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004596, BC004306, BM999307
      Related
      ENST00000590235.5
    2. NR_148387.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004596
    3. NR_148388.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004596
    4. NR_148389.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004596
    5. NR_148390.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC004596
      Related
      ENST00000592825.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      44186972..44191929
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024450929.2XP_024306697.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      pfam00240
      Location:139208
      ubiquitin; Ubiquitin family
    2. XM_047436704.1XP_047292660.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X3

    3. XM_024450930.2XP_024306698.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X5

      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      pfam00240
      Location:130199
      ubiquitin; Ubiquitin family
    4. XM_047436712.1XP_047292668.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X8

    5. XM_047436706.1XP_047292662.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X4

    6. XM_047436707.1XP_047292663.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X4

    7. XM_047436710.1XP_047292666.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X6

      UniProtKB/TrEMBL
      E7ESS3
    8. XM_047436702.1XP_047292658.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X3

    9. XM_047436703.1XP_047292659.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X3

    10. XM_047436711.1XP_047292667.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X8

    11. XM_011525201.3XP_011523503.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X1

      See identical proteins and their annotated locations for XP_011523503.1

      UniProtKB/Swiss-Prot
      B3KU81, Q71RG4, Q8NDI2, Q9BPZ5, Q9HAG3
      UniProtKB/TrEMBL
      B4DFQ1
      Conserved Domains (1) summary
      pfam00240
      Location:176245
      ubiquitin; Ubiquitin family
    12. XM_047436708.1XP_047292664.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X2

    13. XM_047436705.1XP_047292661.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X3

    14. XM_047436699.1XP_047292655.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      B3KU81, Q71RG4, Q8NDI2, Q9BPZ5, Q9HAG3
    15. XM_047436700.1XP_047292656.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      B3KU81, Q71RG4, Q8NDI2, Q9BPZ5, Q9HAG3
    16. XM_047436701.1XP_047292657.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X2

    17. XM_011525200.4XP_011523502.2  transmembrane and ubiquitin-like domain-containing protein 2 isoform X2

    18. XM_011525211.4XP_011523513.2  transmembrane and ubiquitin-like domain-containing protein 2 isoform X7

    19. XM_047436709.1XP_047292665.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X6

      UniProtKB/TrEMBL
      E7ESS3
    20. XM_024450933.2XP_024306701.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X6

      UniProtKB/TrEMBL
      B4DFQ1, E7ESS3
      Conserved Domains (1) summary
      pfam00240
      Location:119188
      ubiquitin; Ubiquitin family

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      45040074..45045031
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054317140.1XP_054173115.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X2

    2. XM_054317136.1XP_054173111.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X3

    3. XM_054317142.1XP_054173117.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X5

    4. XM_054317149.1XP_054173124.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X8

    5. XM_054317147.1XP_054173122.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X7

    6. XM_054317138.1XP_054173113.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X4

    7. XM_054317139.1XP_054173114.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X4

    8. XM_054317143.1XP_054173118.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X6

      UniProtKB/TrEMBL
      E7ESS3
    9. XM_054317134.1XP_054173109.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X3

    10. XM_054317135.1XP_054173110.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X3

    11. XM_054317148.1XP_054173123.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X8

    12. XM_054317133.1XP_054173108.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      B3KU81, Q71RG4, Q8NDI2, Q9BPZ5, Q9HAG3
    13. XM_054317141.1XP_054173116.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X2

    14. XM_054317137.1XP_054173112.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X3

    15. XM_054317129.1XP_054173104.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      B3KU81, Q71RG4, Q8NDI2, Q9BPZ5, Q9HAG3
    16. XM_054317130.1XP_054173105.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X1

      UniProtKB/Swiss-Prot
      B3KU81, Q71RG4, Q8NDI2, Q9BPZ5, Q9HAG3
    17. XM_054317131.1XP_054173106.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X2

    18. XM_054317132.1XP_054173107.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X2

    19. XM_054317146.1XP_054173121.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X7

    20. XM_054317144.1XP_054173119.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X6

      UniProtKB/TrEMBL
      E7ESS3
    21. XM_054317145.1XP_054173120.1  transmembrane and ubiquitin-like domain-containing protein 2 isoform X6

      UniProtKB/TrEMBL
      E7ESS3