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    MROH9 maestro heat like repeat family member 9 [ Homo sapiens (human) ]

    Gene ID: 80133, updated on 10-Dec-2024

    Summary

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    Official Symbol
    MROH9provided by HGNC
    Official Full Name
    maestro heat like repeat family member 9provided by HGNC
    Primary source
    HGNC:HGNC:26287
    See related
    Ensembl:ENSG00000117501 AllianceGenome:HGNC:26287
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ARMC11; C1orf129
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    mouse all
    NEW
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    Genomic context

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    See MROH9 in Genome Data Viewer
    Location:
    1q24.3
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (170935534..171064765)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (170291896..170421107)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (170904675..171033906)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904454 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr1:170803258-170804457 Neighboring gene uncharacterized LOC124904455 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2084 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:171001885-171002420 Neighboring gene alkylated DNA repair protein alkB homolog 8-like Neighboring gene microRNA 1295a Neighboring gene microRNA 1295b Neighboring gene flavin containing dimethylaniline monoxygenase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. Khanna R, et al. FEBS J, 2018 Jun. PMID 29676528
    2. Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy. Sun X, et al. Acta Pharm Sin B, 2022 Feb. PMID 35256949, Free PMC Article
    3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
    4. Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. Huttlin EL, et al. Cell, 2021 May 27. PMID 33961781, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ23550

    General protein information

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    Preferred Names
    maestro heat-like repeat-containing protein family member 9
    Names
    armadillo repeat containing 11

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163629.2 → NP_001157101.1  maestro heat-like repeat-containing protein family member 9 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      BC113392, BX284613, DB096780, DV080473
      Consensus CDS
      CCDS53429.1
      UniProtKB/Swiss-Prot
      Q5TGP6
      Related
      ENSP00000356733.4, ENST00000367759.9
      Conserved Domains (1) summary
      sd00044
      Location:545 → 575
      HEAT; HEAT repeat [structural motif]

    2. NM_025063.4 → NP_079339.2  maestro heat-like repeat-containing protein family member 9 isoform 2

      See identical proteins and their annotated locations for NP_079339.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents an alternate 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AK027203, AL031965, BX284613, DB211602, DB230154
      Consensus CDS
      CCDS41436.1
      UniProtKB/Swiss-Prot
      A0PJM0, A0PJM2, F5GWX6, Q5TGP6, Q9H5D7
      Related
      ENSP00000356732.3, ENST00000367758.7

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      170935534..171064765
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011510006.3 → XP_011508308.1  maestro heat-like repeat-containing protein family member 9 isoform X2

    2. XM_011510005.3 → XP_011508307.1  maestro heat-like repeat-containing protein family member 9 isoform X1

      Conserved Domains (1) summary
      sd00044
      Location:459 → 485
      HEAT; HEAT repeat [structural motif]

    3. XM_011510007.3 → XP_011508309.1  maestro heat-like repeat-containing protein family member 9 isoform X3

      Conserved Domains (1) summary
      sd00044
      Location:194 → 220
      HEAT; HEAT repeat [structural motif]

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      170291896..170421107
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054338857.1 → XP_054194832.1  maestro heat-like repeat-containing protein family member 9 isoform X2

    2. XM_054338856.1 → XP_054194831.1  maestro heat-like repeat-containing protein family member 9 isoform X1

    3. XM_054338858.1 → XP_054194833.1  maestro heat-like repeat-containing protein family member 9 isoform X3

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5TGP6.1 GenPept UniProtKB/Swiss-Prot:Q5TGP6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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