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    Mrpl33 mitochondrial ribosomal protein L33 [ Mus musculus (house mouse) ]

    Gene ID: 66845, updated on 2-Nov-2024

    Summary

    Official Symbol
    Mrpl33provided by MGI
    Official Full Name
    mitochondrial ribosomal protein L33provided by MGI
    Primary source
    MGI:MGI:2137225
    See related
    Ensembl:ENSMUSG00000106918 AllianceGenome:MGI:2137225
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    L33mt; MRP-L33; 0610009M10Rik
    Summary
    Predicted to be a structural constituent of ribosome. Located in mitochondrion. Is expressed in several structures, including brain; early conceptus; endocrine gland; genitourinary system; and liver. Orthologous to human MRPL33 (mitochondrial ribosomal protein L33). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E11.5 (RPKM 49.5), bladder adult (RPKM 44.4) and 21 other tissues See more
    Orthologs
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    Genomic context

    See Mrpl33 in Genome Data Viewer
    Location:
    5 B1; 5 17.27 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (31771295..31779988)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (31613951..31622644)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:31829068-31829342 Neighboring gene solute carrier family 4 (anion exchanger), member 1, adaptor protein Neighboring gene STARR-seq mESC enhancer starr_12773 Neighboring gene expressed sequence AI839979 Neighboring gene STARR-seq mESC enhancer starr_12777 Neighboring gene STARR-positive B cell enhancer ABC_E4750 Neighboring gene STARR-seq mESC enhancer starr_12780 Neighboring gene STARR-seq mESC enhancer starr_12781 Neighboring gene predicted gene, 38424 Neighboring gene ribokinase Neighboring gene microRNA 3473e Neighboring gene STARR-positive B cell enhancer ABC_E11723 Neighboring gene BRISC and BRCA1 A complex member 2 Neighboring gene STARR-seq mESC enhancer starr_12782 Neighboring gene STARR-seq mESC enhancer starr_12783 Neighboring gene STARR-seq mESC enhancer starr_12784 Neighboring gene predicted gene, 52770

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial translation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of mitochondrial large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mitochondrial large ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of mitochondrial large ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    large ribosomal subunit protein bL33m
    Names
    39S ribosomal protein L33, mitochondrial
    NP_080072.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025796.3NP_080072.2  large ribosomal subunit protein bL33m

      See identical proteins and their annotated locations for NP_080072.2

      Status: VALIDATED

      Source sequence(s)
      BC055724, BY112771
      Consensus CDS
      CCDS39056.1
      UniProtKB/Swiss-Prot
      Q9CQP0, Q9D860
      UniProtKB/TrEMBL
      Q8C9M6
      Related
      ENSMUSP00000031024.8, ENSMUST00000031024.14
      Conserved Domains (1) summary
      pfam00471
      Location:1660
      Ribosomal_L33; Ribosomal protein L33

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      31771295..31779988
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)