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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_029659.1Â RefSeqGene
- Range
-
5233..52187
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001199.4 → NP_001190.1  bone morphogenetic protein 1 isoform 1 precursor
See identical proteins and their annotated locations for NP_001190.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1, also known as BMP1-1) represents the shortest transcript and encodes the shorter isoform (1).
- Source sequence(s)
-
BC136679, BE619065, M22488
- Consensus CDS
-
CCDS34856.1
- UniProtKB/TrEMBL
-
Q59F71
- Related
- ENSP00000306121.8, ENST00000306349.13
- Conserved Domains (4) summary
-
- cd04281
Location:121 → 320
- ZnMc_BMP1_TLD; Zinc-dependent metalloprotease; BMP1/TLD-like subfamily. BMP1 (Bone morphogenetic protein 1) and TLD (tolloid)-like metalloproteases play vital roles in extracellular matrix formation, by cleaving precursor proteins such as enzymes, structural proteins, ...
- pfam00431
Location:435 → 544
- CUB; CUB domain
- pfam01400
Location:128 → 321
- Astacin; Astacin (Peptidase family M12A)
- pfam14670
Location:555 → 587
- FXa_inhibition; Coagulation Factor Xa inhibitory site
-
NM_006129.5 → NP_006120.1  bone morphogenetic protein 1 isoform 3 precursor
See identical proteins and their annotated locations for NP_006120.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3, also known as BMP1-3) differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (3) has a distinct C-terminus and is longer than isoform 1.
- Source sequence(s)
-
BC136679, BU627735
- Consensus CDS
-
CCDS6026.1
- UniProtKB/Swiss-Prot
- A8K6F5, B2RN46, D3DSR0, P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38
- UniProtKB/TrEMBL
-
A5PLK9
- Related
- ENSP00000305714.5, ENST00000306385.10
- Conserved Domains (4) summary
-
- cd04281
Location:121 → 320
- ZnMc_BMP1_TLD; Zinc-dependent metalloprotease; BMP1/TLD-like subfamily. BMP1 (Bone morphogenetic protein 1) and TLD (tolloid)-like metalloproteases play vital roles in extracellular matrix formation, by cleaving precursor proteins such as enzymes, structural proteins, ...
- pfam00431
Location:435 → 544
- CUB; CUB domain
- pfam01400
Location:128 → 321
- Astacin; Astacin (Peptidase family M12A)
- pfam14670
Location:707 → 742
- FXa_inhibition; Coagulation Factor Xa inhibitory site
RNA
-
NR_033403.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) has multiple differences compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
BC144366, BU627735
- Related
-
ENST00000520982.5
-
NR_033404.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) uses an alternate splice site in an internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
BC009305, BE619065, M22488
- Related
-
ENST00000518913.5
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000008.11Â Reference GRCh38.p14 Primary Assembly
- Range
-
22165372..22212326
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060932.1Â Alternate T2T-CHM13v2.0
- Range
-
22439316..22486280
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_006128.2: Suppressed sequence
- Description
- NM_006128.2: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
-
NM_006130.1: Suppressed sequence
- Description
- NM_006130.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay candidate.
-
NM_006131.1: Suppressed sequence
- Description
- NM_006131.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay candidate.
-
NM_006132.1: Suppressed sequence
- Description
- NM_006132.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay candidate.