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    Ypel2 yippee like 2 [ Mus musculus (house mouse) ]

    Gene ID: 77864, updated on 28-Oct-2024

    Summary

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    Official Symbol
    Ypel2provided by MGI
    Official Full Name
    yippee like 2provided by MGI
    Primary source
    MGI:MGI:1925114
    See related
    Ensembl:ENSMUSG00000018427 AllianceGenome:MGI:1925114
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6430570G24; E130113K08Rik
    Summary
    Predicted to enable metal ion binding activity. Predicted to be located in nucleolus. Is expressed in forebrain and lens vesicle. Orthologous to human YPEL2 (yippee like 2). [provided by Alliance of Genome Resources, Oct 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 5.5), frontal lobe adult (RPKM 5.5) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ypel2 in Genome Data Viewer
    Location:
    11 C; 11 51.82 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (86827251..86884629, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (86936425..86993805, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 33742 Neighboring gene predicted gene, 38942 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:86706781-86707064 Neighboring gene predicted gene, 46290 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:86738694-86738847 Neighboring gene STARR-seq mESC enhancer starr_30286 Neighboring gene predicted gene, 51915 Neighboring gene predicted gene, 22387 Neighboring gene glycerophosphodiester phosphodiesterase domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. iSyTE: integrated Systems Tool for Eye gene discovery. Lachke SA, et al. Invest Ophthalmol Vis Sci, 2012 Mar. PMID 22323457, Free PMC Article
    2. Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species. Hosono K, et al. Gene, 2004 Sep 29. PMID 15556292
    3. YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10. Hosono K, et al. Genomics, 2010 Aug. PMID 20580816
    4. Evidence Implicating CCNB1IP1, a RING Domain-Containing Protein Required for Meiotic Crossing Over in Mice, as an E3 SUMO Ligase. Strong ER, et al. Genes (Basel), 2010 Dec 2. PMID 21779533, Free PMC Article
    5. A genomic atlas of mouse hypothalamic development. Shimogori T, et al. Nat Neurosci, 2010 Jun. PMID 20436479, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein yippee-like 2
    Names
    ortholog of human yippee-like 2 YPEL2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005341.3 → NP_001005341.1  protein yippee-like 2

      See identical proteins and their annotated locations for NP_001005341.1

      Status: VALIDATED

      Source sequence(s)
      BB656522, BC121190, BY768876
      Consensus CDS
      CCDS25205.1
      UniProtKB/Swiss-Prot
      Q65Z95
      UniProtKB/TrEMBL
      Q0VA86
      Related
      ENSMUSP00000018571.5, ENSMUST00000018571.5
      Conserved Domains (1) summary
      cl13152
      Location:20 → 108
      RLR_C_like; C-terminal domain of Retinoic acid-inducible gene (RIG)-I-like Receptors, Cereblon (CRBN), and similar protein domains

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      86827251..86884629 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011249316.4 → XP_011247618.1  protein yippee-like 2 isoform X1

      See identical proteins and their annotated locations for XP_011247618.1

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q65Z95.1 GenPept UniProtKB/Swiss-Prot:Q65Z95

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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