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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001256702.2 → NP_001243631.1 ubiquitin carboxyl-terminal hydrolase 3 isoform 2
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) lacks an exon in the 5' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- Source sequence(s)
-
AC118274, AK301236, BC065300, DA557812
- Consensus CDS
-
CCDS58370.1
- UniProtKB/TrEMBL
-
H0YKU8
- Related
- ENSP00000445828.1, ENST00000540797.5
- Conserved Domains (3) summary
-
- cl02553
Location:116 → 465
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- pfam00443
Location:114 → 464
- UCH; Ubiquitin carboxyl-terminal hydrolase
- cl09957
Location:29 → 53
- zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
-
NM_006537.4 → NP_006528.2 ubiquitin carboxyl-terminal hydrolase 3 isoform 1
See identical proteins and their annotated locations for NP_006528.2
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) encodes the longer isoform (1).
- Source sequence(s)
-
AC118274, AK314223
- Consensus CDS
-
CCDS32265.1
- UniProtKB/Swiss-Prot
- B4DVU5, F5H1A6, Q8WVD0, Q9Y6I4
- UniProtKB/TrEMBL
-
H0YMI4
- Related
- ENSP00000369681.3, ENST00000380324.8
- Conserved Domains (2) summary
-
- pfam00443
Location:159 → 508
- UCH; Ubiquitin carboxyl-terminal hydrolase
- pfam02148
Location:29 → 105
- zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
RNA
-
NR_046341.2 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) includes an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC118274, AY461579, DA557812
-
NR_046342.2 RNA Sequence
Status: VALIDATED
- Description
- Transcript Variant: This variant (4) includes an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AC118274, BC065300, BX647760, DA557812
- Related
-
ENST00000559192.5
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000015.10 Reference GRCh38.p14 Primary Assembly
- Range
-
63504593..63594633
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047433394.1 → XP_047289350.1 ubiquitin carboxyl-terminal hydrolase 3 isoform X1
- UniProtKB/TrEMBL
- E9PE27, H0YMI4, Q6JHV3
- Related
- ENSP00000268049.7, ENST00000268049.11
-
XM_047433393.1 → XP_047289349.1 ubiquitin carboxyl-terminal hydrolase 3 isoform X1
- UniProtKB/TrEMBL
- E9PE27, H0YMI4, Q6JHV3
-
XM_017022765.2 → XP_016878254.1 ubiquitin carboxyl-terminal hydrolase 3 isoform X1
- UniProtKB/TrEMBL
- E9PE27, H0YMI4, Q6JHV3
- Conserved Domains (3) summary
-
- cl02553
Location:138 → 487
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- pfam00443
Location:136 → 486
- UCH; Ubiquitin carboxyl-terminal hydrolase
- pfam02148
Location:8 → 83
- zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
-
XM_017022763.2 → XP_016878252.1 ubiquitin carboxyl-terminal hydrolase 3 isoform X1
- UniProtKB/TrEMBL
- E9PE27, H0YMI4, Q6JHV3
- Conserved Domains (3) summary
-
- cl02553
Location:138 → 487
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- pfam00443
Location:136 → 486
- UCH; Ubiquitin carboxyl-terminal hydrolase
- pfam02148
Location:8 → 83
- zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
-
XM_017022764.2 → XP_016878253.1 ubiquitin carboxyl-terminal hydrolase 3 isoform X1
- UniProtKB/TrEMBL
- E9PE27, H0YMI4, Q6JHV3
- Conserved Domains (3) summary
-
- cl02553
Location:138 → 487
- Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
- pfam00443
Location:136 → 486
- UCH; Ubiquitin carboxyl-terminal hydrolase
- pfam02148
Location:8 → 83
- zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
-
XM_047433395.1 → XP_047289351.1 ubiquitin carboxyl-terminal hydrolase 3 isoform X2
- UniProtKB/TrEMBL
-
H0YKU8
- Related
- ENSP00000452947.1, ENST00000559257.5
Alternate T2T-CHM13v2.0
Genomic
-
NC_060939.1 Alternate T2T-CHM13v2.0
- Range
-
61311846..61401872
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054379299.1 → XP_054235274.1 ubiquitin carboxyl-terminal hydrolase 3 isoform X1
- UniProtKB/TrEMBL
- E9PE27, H0YMI4, Q6JHV3
-
XM_054379300.1 → XP_054235275.1 ubiquitin carboxyl-terminal hydrolase 3 isoform X1
- UniProtKB/TrEMBL
- E9PE27, H0YMI4, Q6JHV3
-
XM_054379298.1 → XP_054235273.1 ubiquitin carboxyl-terminal hydrolase 3 isoform X1
- UniProtKB/TrEMBL
- E9PE27, H0YMI4, Q6JHV3
-
XM_054379297.1 → XP_054235272.1 ubiquitin carboxyl-terminal hydrolase 3 isoform X1
- UniProtKB/TrEMBL
- E9PE27, H0YMI4, Q6JHV3
-
XM_054379301.1 → XP_054235276.1 ubiquitin carboxyl-terminal hydrolase 3 isoform X1
- UniProtKB/TrEMBL
- E9PE27, H0YMI4, Q6JHV3
-
XM_054379302.1 → XP_054235277.1 ubiquitin carboxyl-terminal hydrolase 3 isoform X2
- UniProtKB/TrEMBL
-
H0YKU8