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    FAM217A family with sequence similarity 217 member A [ Homo sapiens (human) ]

    Gene ID: 222826, updated on 10-Oct-2024

    Summary

    Official Symbol
    FAM217Aprovided by HGNC
    Official Full Name
    family with sequence similarity 217 member Aprovided by HGNC
    Primary source
    HGNC:HGNC:21362
    See related
    Ensembl:ENSG00000145975 AllianceGenome:HGNC:21362
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C6orf146
    Expression
    Restricted expression toward testis (RPKM 7.9) See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See FAM217A in Genome Data Viewer
    Location:
    6p25.2
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (4068367..4087341, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (3937669..3956636, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (4068601..4079371, complement)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124901245 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23894 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23895 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23896 Neighboring gene pre-mRNA processing factor kinase PRP4K Neighboring gene Sharpr-MPRA regulatory region 2502 Neighboring gene uncharacterized LOC124901553 Neighboring gene testis expressed 56, pseudogene Neighboring gene Sharpr-MPRA regulatory region 9692 Neighboring gene enoyl-CoA delta isomerase 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16859 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 16860 Neighboring gene uncharacterized LOC107986559 Neighboring gene ECI2 divergent transcript

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    protein FAM217A
    Names
    uncharacterized protein C6orf146

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173563.3NP_775834.2  protein FAM217A

      See identical proteins and their annotated locations for NP_775834.2

      Status: VALIDATED

      Source sequence(s)
      AL033383, BC039349
      Consensus CDS
      CCDS4489.1
      UniProtKB/Swiss-Prot
      Q5JYK1, Q8IXS0
      Related
      ENSP00000274673.3, ENST00000274673.8
      Conserved Domains (1) summary
      pfam15344
      Location:203400
      FAM217; FAM217 family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      4068367..4087341 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011514415.2XP_011512717.1  protein FAM217A isoform X4

      Related
      ENST00000380188.2
      Conserved Domains (1) summary
      pfam15344
      Location:193390
      FAM217; FAM217 family
    2. XM_017010482.2XP_016865971.1  protein FAM217A isoform X1

      Conserved Domains (1) summary
      pfam15344
      Location:140337
      FAM217; FAM217 family
    3. XM_011514414.4XP_011512716.1  protein FAM217A isoform X1

      See identical proteins and their annotated locations for XP_011512716.1

      Conserved Domains (1) summary
      pfam15344
      Location:140337
      FAM217; FAM217 family
    4. XM_006715025.4XP_006715088.1  protein FAM217A isoform X1

      See identical proteins and their annotated locations for XP_006715088.1

      Conserved Domains (1) summary
      pfam15344
      Location:140337
      FAM217; FAM217 family
    5. XM_011514417.3XP_011512719.1  protein FAM217A isoform X6

      Conserved Domains (1) summary
      pfam15344
      Location:155352
      FAM217; FAM217 family
    6. XM_047418385.1XP_047274341.1  protein FAM217A isoform X1

    7. XM_005248951.5XP_005249008.1  protein FAM217A isoform X3

      Conserved Domains (1) summary
      pfam15344
      Location:194391
      FAM217; FAM217 family
    8. XM_011514416.3XP_011512718.1  protein FAM217A isoform X5

      Conserved Domains (1) summary
      pfam15344
      Location:190387
      FAM217; FAM217 family
    9. XM_006715026.4XP_006715089.1  protein FAM217A isoform X1

      See identical proteins and their annotated locations for XP_006715089.1

      Conserved Domains (1) summary
      pfam15344
      Location:140337
      FAM217; FAM217 family
    10. XM_017010481.2XP_016865970.1  protein FAM217A isoform X3

      Conserved Domains (1) summary
      pfam15344
      Location:194391
      FAM217; FAM217 family
    11. XM_017010480.3XP_016865969.1  protein FAM217A isoform X2

      UniProtKB/TrEMBL
      A0A1W2PRP4

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      3937669..3956636 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054354673.1XP_054210648.1  protein FAM217A isoform X4

    2. XM_054354678.1XP_054210653.1  protein FAM217A isoform X1

    3. XM_054354669.1XP_054210644.1  protein FAM217A isoform X1

    4. XM_054354677.1XP_054210652.1  protein FAM217A isoform X1

    5. XM_054354675.1XP_054210650.1  protein FAM217A isoform X6

    6. XM_054354668.1XP_054210643.1  protein FAM217A isoform X1

    7. XM_054354671.1XP_054210646.1  protein FAM217A isoform X3

    8. XM_054354674.1XP_054210649.1  protein FAM217A isoform X5

    9. XM_054354676.1XP_054210651.1  protein FAM217A isoform X1

    10. XM_054354672.1XP_054210647.1  protein FAM217A isoform X3

    11. XM_054354670.1XP_054210645.1  protein FAM217A isoform X2