U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SCMH1 Scm polycomb group protein homolog 1 [ Homo sapiens (human) ]

    Gene ID: 22955, updated on 10-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SCMH1provided by HGNC
    Official Full Name
    Scm polycomb group protein homolog 1provided by HGNC
    Primary source
    HGNC:HGNC:19003
    See related
    Ensembl:ENSG00000010803 MIM:616396; AllianceGenome:HGNC:19003
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    Scml3
    Summary
    Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in heterochromatin formation and negative regulation of DNA-templated transcription. Predicted to act upstream of or within anterior/posterior pattern specification; chromatin remodeling; and spermatogenesis. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis (RPKM 14.6), ovary (RPKM 12.4) and 25 other tissues See more
    Orthologs
    mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SCMH1 in Genome Data Viewer
    Location:
    1p34.2
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (41027202..41242306, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (40896567..41111749, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (41492874..41707978, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 739 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 740 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 858 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 859 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr1:41472557-41473756 Neighboring gene CTP synthase 1 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_8011 Neighboring gene SLFNL1 antisense RNA 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:41492537-41493455 Neighboring gene MPRA-validated peak193 silencer Neighboring gene schlafen like 1 Neighboring gene ribosomal protein L23a pseudogene 17 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:41622311-41622500 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 860 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 741 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 742 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 743 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:41715456-41715624 Neighboring gene SCMH1 divergent transcript Neighboring gene Sharpr-MPRA regulatory region 3563 Neighboring gene ribosomal protein L36a pseudogene 9 Neighboring gene uncharacterized LOC124904158

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The human homolog of Sex comb on midleg (SCMH1) maps to chromosome 1p34. Berger J, et al. Gene, 1999 Sep 3. PMID 10524249
    2. A novel member of murine Polycomb-group proteins, Sex comb on midleg homolog protein, is highly conserved, and interacts with RAE28/mph1 in vitro. Tomotsune D, et al. Differentiation, 1999 Dec. PMID 10653359
    3. Polycomb-group complex 1 acts as an E3 ubiquitin ligase for Geminin to sustain hematopoietic stem cell activity. Ohtsubo M, et al. Proc Natl Acad Sci U S A, 2008 Jul 29. PMID 18650381, Free PMC Article
    4. Genome-wide association analysis identifies 20 loci that influence adult height. Weedon MN, et al. Nat Genet, 2008 May. PMID 18391952, Free PMC Article
    5. The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions. Luo L, et al. Nature, 2004 Feb 19. PMID 14973489

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Observational study of gene-disease association. (HuGE Navigator)
      Title: The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature.
    Submit: New GeneRIF Correction

    Phenotypes

    Go to the top of the page Help

    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    Genome-wide association analysis identifies 20 loci that influence adult height.
    EBI GWAS Catalog
    Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
    EBI GWAS Catalog
    Hundreds of variants clustered in genomic loci and biological pathways affect human height.
    EBI GWAS Catalog

    Variation

    Go to the top of the page Help

    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in heterochromatin formation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in negative regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in negative regulation of DNA-templated transcription NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    polycomb protein SCMH1
    Names
    sex comb on midleg homolog 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001031694.3 → NP_001026864.1  polycomb protein SCMH1 isoform a

      See identical proteins and their annotated locations for NP_001026864.1

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      Consensus CDS
      CCDS30688.1
      UniProtKB/Swiss-Prot
      B4DRQ8, Q5VT76, Q6IAJ4, Q8WU48, Q96GD3, Q9UKM5, Q9UKM6
      UniProtKB/TrEMBL
      B3KMZ7
      Related
      ENSP00000318094.7, ENST00000326197.11
      Conserved Domains (5) summary
      cd09578
      Location:587 → 657
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:31 → 126
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03247
      Location:233 → 357
      PHA03247; large tegument protein UL36; Provisional
      pfam12140
      Location:358 → 466
      SLED; SLED domain
      pfam17208
      Location:271 → 324
      RBR; RNA binding Region

    2. NM_001172218.2 → NP_001165689.1  polycomb protein SCMH1 isoform c

      See identical proteins and their annotated locations for NP_001165689.1

      Status: VALIDATED

      Source sequence(s)
      AF149046, AL606484, BC009752, BC021252
      Consensus CDS
      CCDS53301.1
      UniProtKB/TrEMBL
      B3KMZ7
      Related
      ENSP00000361677.1, ENST00000372596.5
      Conserved Domains (5) summary
      cd09578
      Location:504 → 574
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:76 → 174
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03247
      Location:172 → 296
      PHA03247; large tegument protein UL36; Provisional
      pfam12140
      Location:297 → 405
      SLED; SLED domain
      pfam17208
      Location:210 → 263
      RBR; RNA binding Region

    3. NM_001172219.2 → NP_001165690.1  polycomb protein SCMH1 isoform d

      Status: VALIDATED

      Source sequence(s)
      AK023124, AL606484, BC021252
      Consensus CDS
      CCDS53304.1
      UniProtKB/TrEMBL
      B3KMZ7
      Related
      ENSP00000337352.5, ENST00000337495.9
      Conserved Domains (3) summary
      cd09578
      Location:575 → 645
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:41 → 136
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03307
      Location:183 → 369
      PHA03307; transcriptional regulator ICP4; Provisional

    4. NM_001172220.2 → NP_001165691.1  polycomb protein SCMH1 isoform c

      See identical proteins and their annotated locations for NP_001165691.1

      Status: VALIDATED

      Source sequence(s)
      AL606484, BC021252, BX640721
      Consensus CDS
      CCDS53301.1
      UniProtKB/TrEMBL
      B3KMZ7
      Conserved Domains (5) summary
      cd09578
      Location:504 → 574
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:76 → 174
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03247
      Location:172 → 296
      PHA03247; large tegument protein UL36; Provisional
      pfam12140
      Location:297 → 405
      SLED; SLED domain
      pfam17208
      Location:210 → 263
      RBR; RNA binding Region

    5. NM_001172221.3 → NP_001165692.1  polycomb protein SCMH1 isoform e

      See identical proteins and their annotated locations for NP_001165692.1

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      Consensus CDS
      CCDS53302.1
      UniProtKB/TrEMBL
      B3KMZ7
      Conserved Domains (5) summary
      cd09578
      Location:526 → 596
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:76 → 174
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03247
      Location:172 → 296
      PHA03247; large tegument protein UL36; Provisional
      pfam12140
      Location:297 → 405
      SLED; SLED domain
      pfam17208
      Location:210 → 263
      RBR; RNA binding Region

    6. NM_001172222.3 → NP_001165693.1  polycomb protein SCMH1 isoform f

      See identical proteins and their annotated locations for NP_001165693.1

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      Consensus CDS
      CCDS53303.1
      UniProtKB/Swiss-Prot
      Q96GD3
      Related
      ENSP00000403974.2, ENST00000456518.3
      Conserved Domains (4) summary
      cd09578
      Location:407 → 477
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00454
      Location:410 → 477
      SAM; Sterile alpha motif
      smart00561
      Location:2 → 79
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:200 → 308
      DUF3588; Protein of unknown function (DUF3588)

    7. NM_001350667.2 → NP_001337596.1  polycomb protein SCMH1 isoform g

      Status: VALIDATED

      Source sequence(s)
      AF149046, AL110502, AL606484, BC009752, BC021252, BG024566
      Conserved Domains (5) summary
      cd09578
      Location:496 → 566
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:46 → 144
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03247
      Location:142 → 266
      PHA03247; large tegument protein UL36; Provisional
      pfam12140
      Location:267 → 375
      SLED; SLED domain
      pfam17208
      Location:180 → 233
      RBR; RNA binding Region

    8. NM_001350668.2 → NP_001337597.1  polycomb protein SCMH1 isoform h

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      Conserved Domains (5) summary
      cd09578
      Location:397 → 467
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      pfam02820
      Location:4 → 67
      MBT; mbt repeat
      pfam12140
      Location:190 → 298
      SLED; SLED domain
      pfam17208
      Location:103 → 156
      RBR; RNA binding Region
      cl26464
      Location:65 → 189
      Atrophin-1; Atrophin-1 family

    9. NM_001394299.1 → NP_001381228.1  polycomb protein SCMH1 isoform i

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      UniProtKB/TrEMBL
      B3KMZ7
      Conserved Domains (3) summary
      cd09578
      Location:565 → 635
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:31 → 126
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03307
      Location:173 → 359
      PHA03307; transcriptional regulator ICP4; Provisional

    10. NM_001394300.1 → NP_001381229.1  polycomb protein SCMH1 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      Consensus CDS
      CCDS30688.1
      UniProtKB/Swiss-Prot
      B4DRQ8, Q5VT76, Q6IAJ4, Q8WU48, Q96GD3, Q9UKM5, Q9UKM6
      UniProtKB/TrEMBL
      B3KMZ7
      Conserved Domains (5) summary
      cd09578
      Location:587 → 657
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:31 → 126
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03247
      Location:233 → 357
      PHA03247; large tegument protein UL36; Provisional
      pfam12140
      Location:358 → 466
      SLED; SLED domain
      pfam17208
      Location:271 → 324
      RBR; RNA binding Region

    11. NM_001394301.1 → NP_001381230.1  polycomb protein SCMH1 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      Consensus CDS
      CCDS30688.1
      UniProtKB/Swiss-Prot
      B4DRQ8, Q5VT76, Q6IAJ4, Q8WU48, Q96GD3, Q9UKM5, Q9UKM6
      UniProtKB/TrEMBL
      B3KMZ7
      Conserved Domains (5) summary
      cd09578
      Location:587 → 657
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:31 → 126
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03247
      Location:233 → 357
      PHA03247; large tegument protein UL36; Provisional
      pfam12140
      Location:358 → 466
      SLED; SLED domain
      pfam17208
      Location:271 → 324
      RBR; RNA binding Region

    12. NM_001394302.1 → NP_001381231.1  polycomb protein SCMH1 isoform a

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      Consensus CDS
      CCDS30688.1
      UniProtKB/Swiss-Prot
      B4DRQ8, Q5VT76, Q6IAJ4, Q8WU48, Q96GD3, Q9UKM5, Q9UKM6
      UniProtKB/TrEMBL
      B3KMZ7
      Conserved Domains (5) summary
      cd09578
      Location:587 → 657
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:31 → 126
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03247
      Location:233 → 357
      PHA03247; large tegument protein UL36; Provisional
      pfam12140
      Location:358 → 466
      SLED; SLED domain
      pfam17208
      Location:271 → 324
      RBR; RNA binding Region

    13. NM_001394303.1 → NP_001381232.1  polycomb protein SCMH1 isoform e

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      Consensus CDS
      CCDS53302.1
      UniProtKB/TrEMBL
      B3KMZ7
      Conserved Domains (5) summary
      cd09578
      Location:526 → 596
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:76 → 174
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03247
      Location:172 → 296
      PHA03247; large tegument protein UL36; Provisional
      pfam12140
      Location:297 → 405
      SLED; SLED domain
      pfam17208
      Location:210 → 263
      RBR; RNA binding Region

    14. NM_001394304.1 → NP_001381233.1  polycomb protein SCMH1 isoform i

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      UniProtKB/TrEMBL
      B3KMZ7
      Conserved Domains (3) summary
      cd09578
      Location:565 → 635
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:31 → 126
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03307
      Location:173 → 359
      PHA03307; transcriptional regulator ICP4; Provisional

    15. NM_001394305.1 → NP_001381234.1  polycomb protein SCMH1 isoform i

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      UniProtKB/TrEMBL
      B3KMZ7
      Conserved Domains (3) summary
      cd09578
      Location:565 → 635
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:31 → 126
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03307
      Location:173 → 359
      PHA03307; transcriptional regulator ICP4; Provisional

    16. NM_001394306.1 → NP_001381235.1  polycomb protein SCMH1 isoform i

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      UniProtKB/TrEMBL
      B3KMZ7
      Conserved Domains (3) summary
      cd09578
      Location:565 → 635
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:31 → 126
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03307
      Location:173 → 359
      PHA03307; transcriptional regulator ICP4; Provisional

    17. NM_001394307.1 → NP_001381236.1  polycomb protein SCMH1 isoform j

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      UniProtKB/TrEMBL
      B3KMZ7
      Conserved Domains (5) summary
      cd09578
      Location:540 → 610
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:90 → 188
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03247
      Location:186 → 310
      PHA03247; large tegument protein UL36; Provisional
      pfam12140
      Location:311 → 419
      SLED; SLED domain
      pfam17208
      Location:224 → 277
      RBR; RNA binding Region

    18. NM_001394308.1 → NP_001381237.1  polycomb protein SCMH1 isoform k

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      Consensus CDS
      CCDS90927.1
      UniProtKB/TrEMBL
      A0A8Q3SHR9, B3KMZ7
      Related
      ENSP00000511814.1, ENST00000695336.1
      Conserved Domains (3) summary
      cd09578
      Location:477 → 547
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:41 → 136
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:248 → 356
      SLED; SLED domain

    19. NM_001394309.1 → NP_001381238.1  polycomb protein SCMH1 isoform l

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      Conserved Domains (5) summary
      cd09578
      Location:419 → 489
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      PHA03247
      Location:65 → 189
      PHA03247; large tegument protein UL36; Provisional
      pfam02820
      Location:4 → 67
      MBT; mbt repeat
      pfam12140
      Location:190 → 298
      SLED; SLED domain
      pfam17208
      Location:103 → 156
      RBR; RNA binding Region

    20. NM_001394311.1 → NP_001381240.1  polycomb protein SCMH1 isoform m

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484
      Consensus CDS
      CCDS90928.1
      UniProtKB/TrEMBL
      A0A8Q3SHN2, B3KMZ7
      Related
      ENSP00000511813.1, ENST00000695335.1
      Conserved Domains (5) summary
      cd09578
      Location:597 → 667
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:41 → 136
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03247
      Location:243 → 367
      PHA03247; large tegument protein UL36; Provisional
      pfam12140
      Location:368 → 476
      SLED; SLED domain
      pfam17208
      Location:281 → 334
      RBR; RNA binding Region

    21. NM_012236.4 → NP_036368.1  polycomb protein SCMH1 isoform b

      See identical proteins and their annotated locations for NP_036368.1

      Status: VALIDATED

      Source sequence(s)
      AF149045, AL606484, BC009752, BC021252
      Consensus CDS
      CCDS461.1
      UniProtKB/TrEMBL
      B3KMZ7
      Related
      ENSP00000361678.1, ENST00000372597.5
      Conserved Domains (5) summary
      cd09578
      Location:518 → 588
      SAM_Scm; SAM domain of Scm proteins of Polycomb group
      smart00561
      Location:90 → 188
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      PHA03247
      Location:186 → 310
      PHA03247; large tegument protein UL36; Provisional
      pfam12140
      Location:311 → 419
      SLED; SLED domain
      pfam17208
      Location:224 → 277
      RBR; RNA binding Region

    RNA

    1. NR_135092.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL110502, AL391730, AL606484

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      41027202..41242306 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047449591.1 → XP_047305547.1  polycomb protein SCMH1 isoform X10

      UniProtKB/TrEMBL
      B3KMZ7

    2. XM_011541034.2 → XP_011539336.1  polycomb protein SCMH1 isoform X4

      UniProtKB/TrEMBL
      B3KMZ7
      Conserved Domains (2) summary
      smart00561
      Location:41 → 136
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:368 → 476
      DUF3588; Protein of unknown function (DUF3588)

    3. XM_047449589.1 → XP_047305545.1  polycomb protein SCMH1 isoform X9

      UniProtKB/TrEMBL
      A0A8Q3SHR9, B3KMZ7

    4. XM_047449568.1 → XP_047305524.1  polycomb protein SCMH1 isoform X3

      UniProtKB/TrEMBL
      B3KMZ7

    5. XM_047449564.1 → XP_047305520.1  polycomb protein SCMH1 isoform X1

      UniProtKB/TrEMBL
      A0A8Q3SHN2, B3KMZ7

    6. XM_047449565.1 → XP_047305521.1  polycomb protein SCMH1 isoform X1

      UniProtKB/TrEMBL
      A0A8Q3SHN2, B3KMZ7

    7. XM_047449567.1 → XP_047305523.1  polycomb protein SCMH1 isoform X2

      UniProtKB/Swiss-Prot
      B4DRQ8, Q5VT76, Q6IAJ4, Q8WU48, Q96GD3, Q9UKM5, Q9UKM6
      UniProtKB/TrEMBL
      B3KMZ7

    8. XM_047449577.1 → XP_047305533.1  polycomb protein SCMH1 isoform X5

      UniProtKB/TrEMBL
      B3KMZ7

    9. XM_047449578.1 → XP_047305534.1  polycomb protein SCMH1 isoform X6

      UniProtKB/TrEMBL
      B3KMZ7
      Related
      ENSP00000361676.1, ENST00000372595.5

    10. XM_047449583.1 → XP_047305539.1  polycomb protein SCMH1 isoform X6

      UniProtKB/TrEMBL
      B3KMZ7

    11. XM_047449587.1 → XP_047305543.1  polycomb protein SCMH1 isoform X7

      UniProtKB/TrEMBL
      B3KMZ7

    12. XM_047449588.1 → XP_047305544.1  polycomb protein SCMH1 isoform X8

      UniProtKB/TrEMBL
      B3KMZ7, B4DWE6
      Related
      ENSP00000511815.1, ENST00000695337.1

    13. XM_047449601.1 → XP_047305557.1  polycomb protein SCMH1 isoform X12

    14. XM_011541040.3 → XP_011539342.1  polycomb protein SCMH1 isoform X11

      Conserved Domains (2) summary
      smart00561
      Location:41 → 136
      MBT; Present in Drosophila Scm, l(3)mbt, and vertebrate SCML2
      pfam12140
      Location:368 → 476
      DUF3588; Protein of unknown function (DUF3588)

    RNA

    1. XR_946584.3 RNA Sequence

    2. XR_007096354.1 RNA Sequence

    3. XR_002959761.2 RNA Sequence

    4. XR_007096355.1 RNA Sequence

    5. XR_007096359.1 RNA Sequence

    6. XR_007096358.1 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      40896567..41111749 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054335231.1 → XP_054191206.1  polycomb protein SCMH1 isoform X10

      UniProtKB/TrEMBL
      B3KMZ7

    2. XM_054335223.1 → XP_054191198.1  polycomb protein SCMH1 isoform X4

      UniProtKB/TrEMBL
      B3KMZ7

    3. XM_054335230.1 → XP_054191205.1  polycomb protein SCMH1 isoform X9

      UniProtKB/TrEMBL
      A0A8Q3SHR9, B3KMZ7

    4. XM_054335222.1 → XP_054191197.1  polycomb protein SCMH1 isoform X3

      UniProtKB/TrEMBL
      B3KMZ7

    5. XM_054335219.1 → XP_054191194.1  polycomb protein SCMH1 isoform X1

      UniProtKB/TrEMBL
      A0A8Q3SHN2, B3KMZ7

    6. XM_054335220.1 → XP_054191195.1  polycomb protein SCMH1 isoform X1

      UniProtKB/TrEMBL
      A0A8Q3SHN2, B3KMZ7

    7. XM_054335221.1 → XP_054191196.1  polycomb protein SCMH1 isoform X2

      UniProtKB/Swiss-Prot
      B4DRQ8, Q5VT76, Q6IAJ4, Q8WU48, Q96GD3, Q9UKM5, Q9UKM6
      UniProtKB/TrEMBL
      B3KMZ7

    8. XM_054335224.1 → XP_054191199.1  polycomb protein SCMH1 isoform X5

      UniProtKB/TrEMBL
      B3KMZ7

    9. XM_054335225.1 → XP_054191200.1  polycomb protein SCMH1 isoform X6

      UniProtKB/TrEMBL
      B3KMZ7

    10. XM_054335226.1 → XP_054191201.1  polycomb protein SCMH1 isoform X6

      UniProtKB/TrEMBL
      B3KMZ7

    11. XM_054335227.1 → XP_054191202.1  polycomb protein SCMH1 isoform X13

      UniProtKB/TrEMBL
      B3KMZ7

    12. XM_054335228.1 → XP_054191203.1  polycomb protein SCMH1 isoform X7

      UniProtKB/TrEMBL
      B3KMZ7

    13. XM_054335229.1 → XP_054191204.1  polycomb protein SCMH1 isoform X8

      UniProtKB/TrEMBL
      B3KMZ7, B4DWE6

    14. XM_054335236.1 → XP_054191211.1  polycomb protein SCMH1 isoform X12

    15. XM_054335232.1 → XP_054191207.1  polycomb protein SCMH1 isoform X11

    16. XM_054335233.1 → XP_054191208.1  polycomb protein SCMH1 isoform X14

    17. XM_054335235.1 → XP_054191210.1  polycomb protein SCMH1 isoform X16

    18. XM_054335234.1 → XP_054191209.1  polycomb protein SCMH1 isoform X15

    RNA

    1. XR_008485963.1 RNA Sequence

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q96GD3.1 GenPept UniProtKB/Swiss-Prot:Q96GD3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous