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    RBFOX2 RNA binding fox-1 homolog 2 [ Homo sapiens (human) ]

    Gene ID: 23543, updated on 3-Dec-2024

    Summary

    Official Symbol
    RBFOX2provided by HGNC
    Official Full Name
    RNA binding fox-1 homolog 2provided by HGNC
    Primary source
    HGNC:HGNC:9906
    See related
    Ensembl:ENSG00000100320 MIM:612149; AllianceGenome:HGNC:9906
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    RTA; fxh; FOX2; RBM9; Fox-2; HNRBP2; HRNBP2; dJ106I20.3
    Summary
    This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
    Expression
    Ubiquitous expression in endometrium (RPKM 22.3), ovary (RPKM 20.4) and 23 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See RBFOX2 in Genome Data Viewer
    Location:
    22q12.3
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (35738736..36028824, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (36198484..36488569, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (36134783..36424872, complement)

    Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein S16 pseudogene 3 Neighboring gene apolipoprotein L5 Neighboring gene ribosomal protein L41 pseudogene 3 Neighboring gene H3K27ac hESC enhancer GRCh37_chr22:36278945-36279446 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:36312425-36313104 Neighboring gene NADH:ubiquinone oxidoreductase subunit A9 pseudogene 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13660 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr22:36431275-36432018 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr22:36448074-36449273 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:36481448-36482174 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:36512656-36513156 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:36513157-36513657 Neighboring gene Sharpr-MPRA regulatory region 8708 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:36528024-36528524 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr22:36530251-36531450 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:36537001-36537502 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:36537503-36538002 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:36552799-36553402 Neighboring gene NANOG hESC enhancer GRCh37_chr22:36557722-36558295 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18916 Neighboring gene apolipoprotein L3 Neighboring gene MT-CO1 pseudogene 20

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription factor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables RNA binding HDA PubMed 
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transcription corepressor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in RNA metabolic process TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in estrogen receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of alternative mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of cell population proliferation TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    RNA binding protein fox-1 homolog 2
    Names
    RNA binding protein, fox-1 homolog 2
    RNA-binding motif protein 9
    fox-1 homolog B
    fox-1 homologue
    hexaribonucleotide-binding protein 2
    repressor of tamoxifen transcriptional activity

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_029628.2 RefSeqGene

      Range
      5000..295088
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001031695.4NP_001026865.1  RNA binding protein fox-1 homolog 2 isoform 1

      See identical proteins and their annotated locations for NP_001026865.1

      Status: REVIEWED

      Source sequence(s)
      AA610054, AL049748, BC025281, DA493176
      Consensus CDS
      CCDS46700.1
      UniProtKB/Swiss-Prot
      A4F5G8, A8K5Z5, B0QYY8, B0QYY9, O43251, Q0PRL5, Q0VH35, Q5TF71, Q6IC09, Q8TD00, Q8WYB1, Q96DZ6, Q96NL7, Q9UGW4, Q9UH33
      Related
      ENSP00000391670.2, ENST00000449924.6
      Conserved Domains (3) summary
      cd12407
      Location:111186
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:255352
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl25887
      Location:95261
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    2. NM_001082576.3NP_001076045.1  RNA binding protein fox-1 homolog 2 isoform 3

      See identical proteins and their annotated locations for NP_001076045.1

      Status: REVIEWED

      Source sequence(s)
      AA610054, AL049748, CR456559, DA493176
      Consensus CDS
      CCDS46701.1
      UniProtKB/Swiss-Prot
      A4F5G8, A8K5Z5, B0QYY8, B0QYY9, O43251, Q0PRL5, Q0VH35, Q5TF71, Q6IC09, Q8TD00, Q8WYB1, Q96DZ6, Q96NL7, Q9UGW4, Q9UH33
      Related
      ENSP00000405651.2, ENST00000416721.6
      Conserved Domains (3) summary
      TIGR01645
      Location:95247
      half-pint; poly-U binding splicing factor, half-pint family
      pfam12414
      Location:251348
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:111186
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
    3. NM_001082577.3NP_001076046.1  RNA binding protein fox-1 homolog 2 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AA610054, AL049748, AY960684, DA493176
      Consensus CDS
      CCDS46699.1
      UniProtKB/TrEMBL
      F8WSN4
      Related
      ENSP00000407855.2, ENST00000414461.6
      Conserved Domains (3) summary
      COG0724
      Location:70195
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:111186
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:255303
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    4. NM_001082578.4NP_001076047.2  RNA binding protein fox-1 homolog 2 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z95114
      Consensus CDS
      CCDS43013.1
      UniProtKB/TrEMBL
      A0A0G2JRA5
      Related
      ENSP00000413035.2, ENST00000438146.7
      Conserved Domains (3) summary
      TIGR01645
      Location:166332
      half-pint; poly-U binding splicing factor, half-pint family
      pfam12414
      Location:326423
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:182257
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
    5. NM_001082579.3NP_001076048.2  RNA binding protein fox-1 homolog 2 isoform 6

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z95114
      UniProtKB/Swiss-Prot
      A4F5G8, A8K5Z5, B0QYY8, B0QYY9, O43251, Q0PRL5, Q0VH35, Q5TF71, Q6IC09, Q8TD00, Q8WYB1, Q96DZ6, Q96NL7, Q9UGW4, Q9UH33
      Conserved Domains (3) summary
      TIGR01645
      Location:165331
      half-pint; poly-U binding splicing factor, half-pint family
      pfam12414
      Location:325422
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:181256
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
    6. NM_001349982.2NP_001336911.1  RNA binding protein fox-1 homolog 2 isoform 8

      Status: REVIEWED

      Source sequence(s)
      AA610054, AL035800, AL049748, CR456559, DA776762, HY155887, HY351263
      UniProtKB/TrEMBL
      B0QYY4
      Conserved Domains (3) summary
      cd12407
      Location:133208
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:273330
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl25887
      Location:117269
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    7. NM_001349983.2NP_001336912.1  RNA binding protein fox-1 homolog 2 isoform 7

      Status: REVIEWED

      Source sequence(s)
      AA610054, AL049748, CN399960, CR456559, HY351263
      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (3) summary
      cd12407
      Location:111186
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:251308
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl25887
      Location:95247
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    8. NM_001349989.2NP_001336918.1  RNA binding protein fox-1 homolog 2 isoform 9

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z82217
      UniProtKB/Swiss-Prot
      A4F5G8, A8K5Z5, B0QYY8, B0QYY9, O43251, Q0PRL5, Q0VH35, Q5TF71, Q6IC09, Q8TD00, Q8WYB1, Q96DZ6, Q96NL7, Q9UGW4, Q9UH33
      Conserved Domains (3) summary
      cd12407
      Location:133208
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:277374
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl25887
      Location:117283
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    9. NM_001349990.2NP_001336919.1  RNA binding protein fox-1 homolog 2 isoform 10

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z82217
      UniProtKB/Swiss-Prot
      A4F5G8, A8K5Z5, B0QYY8, B0QYY9, O43251, Q0PRL5, Q0VH35, Q5TF71, Q6IC09, Q8TD00, Q8WYB1, Q96DZ6, Q96NL7, Q9UGW4, Q9UH33
      Conserved Domains (3) summary
      TIGR01645
      Location:117269
      half-pint; poly-U binding splicing factor, half-pint family
      pfam12414
      Location:273370
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:133208
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
    10. NM_001349991.2NP_001336920.1  RNA binding protein fox-1 homolog 2 isoform 11

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z82217
      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (3) summary
      cd12407
      Location:133208
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:277334
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl25887
      Location:117283
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    11. NM_001349992.2NP_001336921.1  RNA binding protein fox-1 homolog 2 isoform 12

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z82217
      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (3) summary
      cd12407
      Location:133208
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:277325
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl25887
      Location:117283
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    12. NM_001349994.2NP_001336923.1  RNA binding protein fox-1 homolog 2 isoform 13

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z82217
      UniProtKB/TrEMBL
      B0QYY4
      Conserved Domains (2) summary
      cd12407
      Location:133208
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:273321
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    13. NM_001349995.2NP_001336924.1  RNA binding protein fox-1 homolog 2 isoform 14

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z82217
      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (3) summary
      COG0724
      Location:92167
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      pfam12414
      Location:246294
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl17169
      Location:133172
      RRM_SF; RNA recognition motif (RRM) superfamily
    14. NM_001349996.2NP_001336925.1  RNA binding protein fox-1 homolog 2 isoform 15

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z82217
      UniProtKB/TrEMBL
      A0A0G2JRA5
      Conserved Domains (2) summary
      cd12407
      Location:134208
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:273370
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    15. NM_001349997.2NP_001336926.1  RNA binding protein fox-1 homolog 2 isoform 16

      Status: REVIEWED

      Source sequence(s)
      AK291460, AL049748
      UniProtKB/TrEMBL
      A0A0G2JRA5
      Conserved Domains (3) summary
      cd12407
      Location:112187
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:256353
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl25887
      Location:96262
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    16. NM_001349998.2NP_001336927.1  RNA binding protein fox-1 homolog 2 isoform 17

      Status: REVIEWED

      Source sequence(s)
      AB649123, AL049748, AL079295
      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (3) summary
      cd12407
      Location:111186
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:255312
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl25887
      Location:95261
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    17. NM_001349999.2NP_001336928.2  RNA binding protein fox-1 homolog 2 isoform 18

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z95114
      Consensus CDS
      CCDS93157.1
      UniProtKB/TrEMBL
      A0A0G2JRA5, A0A8Q3WKT3
      Related
      ENSP00000512219.1, ENST00000695854.1
      Conserved Domains (2) summary
      pfam12414
      Location:322419
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:182257
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
    18. NM_001394108.1NP_001381037.1  RNA binding protein fox-1 homolog 2 isoform 19

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z95114
      UniProtKB/Swiss-Prot
      A4F5G8, A8K5Z5, B0QYY8, B0QYY9, O43251, Q0PRL5, Q0VH35, Q5TF71, Q6IC09, Q8TD00, Q8WYB1, Q96DZ6, Q96NL7, Q9UGW4, Q9UH33
      Conserved Domains (2) summary
      smart00360
      Location:182251
      RRM; RNA recognition motif
      TIGR01648
      Location:173379
      hnRNP-R-Q; heterogeneous nuclear ribonucleoprotein R, Q family
    19. NM_001394109.1NP_001381038.1  RNA binding protein fox-1 homolog 2 isoform 20

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z95114
      UniProtKB/TrEMBL
      A0A0G2JRA5
      Conserved Domains (1) summary
      smart00360
      Location:183216
      RRM; RNA recognition motif
    20. NM_001394110.1NP_001381039.1  RNA binding protein fox-1 homolog 2 isoform 21

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z95114
      UniProtKB/Swiss-Prot
      A4F5G8, A8K5Z5, B0QYY8, B0QYY9, O43251, Q0PRL5, Q0VH35, Q5TF71, Q6IC09, Q8TD00, Q8WYB1, Q96DZ6, Q96NL7, Q9UGW4, Q9UH33
      Conserved Domains (2) summary
      smart00360
      Location:182216
      RRM; RNA recognition motif
      COG0724
      Location:140215
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    21. NM_001394111.1NP_001381040.1  RNA binding protein fox-1 homolog 2 isoform 22

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z95114
      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (2) summary
      smart00360
      Location:182216
      RRM; RNA recognition motif
      COG0724
      Location:140215
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    22. NM_001394112.1NP_001381041.1  RNA binding protein fox-1 homolog 2 isoform 23

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z95114
      UniProtKB/TrEMBL
      A0A0G2JRA5
      Conserved Domains (2) summary
      smart00360
      Location:183252
      RRM; RNA recognition motif
      TIGR01648
      Location:174380
      hnRNP-R-Q; heterogeneous nuclear ribonucleoprotein R, Q family
    23. NM_001394113.1NP_001381042.1  RNA binding protein fox-1 homolog 2 isoform 24

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z95114
      UniProtKB/Swiss-Prot
      A4F5G8, A8K5Z5, B0QYY8, B0QYY9, O43251, Q0PRL5, Q0VH35, Q5TF71, Q6IC09, Q8TD00, Q8WYB1, Q96DZ6, Q96NL7, Q9UGW4, Q9UH33
      Conserved Domains (2) summary
      pfam12414
      Location:321418
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:181256
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
    24. NM_001394114.1NP_001381043.1  RNA binding protein fox-1 homolog 2 isoform 25

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z95114
      UniProtKB/TrEMBL
      A0A8Q3SI75
      Conserved Domains (2) summary
      pfam12414
      Location:322370
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:182257
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
    25. NM_001394115.1NP_001381044.1  RNA binding protein fox-1 homolog 2 isoform 26

      Status: REVIEWED

      Source sequence(s)
      AL049748, AL079295, Z95114
      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (2) summary
      pfam12414
      Location:321369
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cd12407
      Location:181256
      RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
    26. NM_014309.4NP_055124.1  RNA binding protein fox-1 homolog 2 isoform 2

      See identical proteins and their annotated locations for NP_055124.1

      Status: REVIEWED

      Source sequence(s)
      AA610054, AL009266, AL049748, DA493176
      Consensus CDS
      CCDS13921.1
      UniProtKB/TrEMBL
      A0A8Q3SI75
      Related
      ENSP00000384944.2, ENST00000405409.6
      Conserved Domains (3) summary
      COG0724
      Location:95196
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:112187
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:252300
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

      Range
      35738736..36028824 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005261429.3XP_005261486.1  RNA binding protein fox-1 homolog 2 isoform X4

      UniProtKB/TrEMBL
      B0QYY4
      Conserved Domains (3) summary
      COG0724
      Location:140265
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:181256
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:321378
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    2. XM_006724186.3XP_006724249.1  RNA binding protein fox-1 homolog 2 isoform X2

      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (3) summary
      COG0724
      Location:140265
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:181256
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:325382
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    3. XM_005261430.3XP_005261487.1  RNA binding protein fox-1 homolog 2 isoform X6

      UniProtKB/TrEMBL
      A0A0G2JRA5
      Conserved Domains (3) summary
      COG0724
      Location:165266
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:182257
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:322420
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    4. XM_005261428.3XP_005261485.1  RNA binding protein fox-1 homolog 2 isoform X3

      UniProtKB/TrEMBL
      B0QYY4
      Conserved Domains (3) summary
      COG0724
      Location:165266
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:182257
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:322379
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    5. XM_006724188.3XP_006724251.1  RNA binding protein fox-1 homolog 2 isoform X8

      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (3) summary
      COG0724
      Location:165266
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:182257
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:326374
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    6. XM_006724187.3XP_006724250.1  RNA binding protein fox-1 homolog 2 isoform X5

      UniProtKB/TrEMBL
      A0A0G2JRA5
      Conserved Domains (3) summary
      COG0724
      Location:165266
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:182257
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:326424
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    7. XM_006724185.3XP_006724248.1  RNA binding protein fox-1 homolog 2 isoform X1

      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (3) summary
      COG0724
      Location:165266
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:182257
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:326383
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    8. XM_017028686.1XP_016884175.1  RNA binding protein fox-1 homolog 2 isoform X7

      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (3) summary
      COG0724
      Location:107208
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:124199
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:268325
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    9. XM_047441254.1XP_047297210.1  RNA binding protein fox-1 homolog 2 isoform X22

      UniProtKB/TrEMBL
      A0A8Q3SI75
    10. XM_047441251.1XP_047297207.1  RNA binding protein fox-1 homolog 2 isoform X16

      UniProtKB/TrEMBL
      A0A0G2JRA5
    11. XM_047441250.1XP_047297206.1  RNA binding protein fox-1 homolog 2 isoform X12

      UniProtKB/TrEMBL
      B0QYY4
    12. XM_006724189.4XP_006724252.1  RNA binding protein fox-1 homolog 2 isoform X11

      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (3) summary
      COG0724
      Location:117218
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:134209
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:278335
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    13. XM_017028687.3XP_016884176.1  RNA binding protein fox-1 homolog 2 isoform X9

      UniProtKB/TrEMBL
      F8WSN4
    14. XM_024452188.2XP_024307956.1  RNA binding protein fox-1 homolog 2 isoform X10

      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (3) summary
      cd12407
      Location:155230
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:299356
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl25887
      Location:139305
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    15. XM_047441260.1XP_047297216.1  RNA binding protein fox-1 homolog 2 isoform X31

      UniProtKB/TrEMBL
      B0QYY4
    16. XM_047441258.1XP_047297214.1  RNA binding protein fox-1 homolog 2 isoform X28

      UniProtKB/TrEMBL
      A8MVJ8, B0QYV1
    17. XM_024452191.2XP_024307959.1  RNA binding protein fox-1 homolog 2 isoform X27

      UniProtKB/TrEMBL
      A8MVJ8, B0QYV1
      Conserved Domains (3) summary
      cd12407
      Location:107182
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:247344
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
      cl25887
      Location:91243
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    18. XM_047441253.1XP_047297209.1  RNA binding protein fox-1 homolog 2 isoform X21

      UniProtKB/TrEMBL
      B0QYY4
      Related
      ENSP00000352328.4, ENST00000359369.8
    19. XM_047441252.1XP_047297208.1  RNA binding protein fox-1 homolog 2 isoform X20

      UniProtKB/TrEMBL
      F8WSN4
    20. XM_047441259.1XP_047297215.1  RNA binding protein fox-1 homolog 2 isoform X30

      UniProtKB/TrEMBL
      A0A8Q3SI75
    21. XM_006724192.3XP_006724255.1  RNA binding protein fox-1 homolog 2 isoform X18

      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (3) summary
      COG0724
      Location:91192
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:108183
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:252309
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    22. XM_047441257.1XP_047297213.1  RNA binding protein fox-1 homolog 2 isoform X26

      UniProtKB/Swiss-Prot
      A4F5G8, A8K5Z5, B0QYY8, B0QYY9, O43251, Q0PRL5, Q0VH35, Q5TF71, Q6IC09, Q8TD00, Q8WYB1, Q96DZ6, Q96NL7, Q9UGW4, Q9UH33
    23. XM_017028691.2XP_016884180.1  RNA binding protein fox-1 homolog 2 isoform X14

      UniProtKB/TrEMBL
      F8WSN4
    24. XM_017028690.2XP_016884179.1  RNA binding protein fox-1 homolog 2 isoform X13

      UniProtKB/TrEMBL
      F8WSN4
    25. XM_017028698.2XP_016884187.1  RNA binding protein fox-1 homolog 2 isoform X29

      UniProtKB/TrEMBL
      F8WSN4
    26. XM_047441256.1XP_047297212.1  RNA binding protein fox-1 homolog 2 isoform X25

      UniProtKB/Swiss-Prot
      A4F5G8, A8K5Z5, B0QYY8, B0QYY9, O43251, Q0PRL5, Q0VH35, Q5TF71, Q6IC09, Q8TD00, Q8WYB1, Q96DZ6, Q96NL7, Q9UGW4, Q9UH33
    27. XM_047441255.1XP_047297211.1  RNA binding protein fox-1 homolog 2 isoform X23

      UniProtKB/TrEMBL
      A8MVJ8, B0QYV1
    28. XM_017028696.2XP_016884185.1  RNA binding protein fox-1 homolog 2 isoform X24

      UniProtKB/TrEMBL
      A8MVJ8, B0QYV1
      Related
      ENSP00000512183.1, ENST00000695803.1
      Conserved Domains (3) summary
      TIGR01645
      Location:96248
      half-pint; poly-U binding splicing factor, half-pint family
      cd12407
      Location:112187
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:252349
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    29. XM_017028693.2XP_016884182.1  RNA binding protein fox-1 homolog 2 isoform X17

      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (3) summary
      COG0724
      Location:95196
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:112187
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:252309
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    30. XM_006724191.2XP_006724254.1  RNA binding protein fox-1 homolog 2 isoform X15

      UniProtKB/TrEMBL
      F8WSN4
      Conserved Domains (3) summary
      COG0724
      Location:95196
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:112187
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:256313
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal
    31. XM_006724193.4XP_006724256.1  RNA binding protein fox-1 homolog 2 isoform X19

      UniProtKB/TrEMBL
      A0A0G2JRA5
      Conserved Domains (3) summary
      COG0724
      Location:165266
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12407
      Location:182257
      RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins
      pfam12414
      Location:326383
      Fox-1_C; Calcitonin gene-related peptide regulator C terminal

    Reference GRCh38.p14 ALT_REF_LOCI_1

    Genomic

    1. NT_187630.1 Reference GRCh38.p14 ALT_REF_LOCI_1

      Range
      59734..259897 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060946.1 Alternate T2T-CHM13v2.0

      Range
      36198484..36488569 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054325369.1XP_054181344.1  RNA binding protein fox-1 homolog 2 isoform X4

      UniProtKB/TrEMBL
      B0QYY4
    2. XM_054325367.1XP_054181342.1  RNA binding protein fox-1 homolog 2 isoform X2

      UniProtKB/TrEMBL
      F8WSN4
    3. XM_054325371.1XP_054181346.1  RNA binding protein fox-1 homolog 2 isoform X6

      UniProtKB/TrEMBL
      A0A0G2JRA5
    4. XM_054325368.1XP_054181343.1  RNA binding protein fox-1 homolog 2 isoform X3

      UniProtKB/TrEMBL
      B0QYY4
    5. XM_054325373.1XP_054181348.1  RNA binding protein fox-1 homolog 2 isoform X8

      UniProtKB/TrEMBL
      F8WSN4
    6. XM_054325370.1XP_054181345.1  RNA binding protein fox-1 homolog 2 isoform X5

      UniProtKB/TrEMBL
      A0A0G2JRA5
    7. XM_054325366.1XP_054181341.1  RNA binding protein fox-1 homolog 2 isoform X1

      UniProtKB/TrEMBL
      F8WSN4
    8. XM_054325372.1XP_054181347.1  RNA binding protein fox-1 homolog 2 isoform X7

      UniProtKB/TrEMBL
      F8WSN4
    9. XM_054325387.1XP_054181362.1  RNA binding protein fox-1 homolog 2 isoform X22

      UniProtKB/TrEMBL
      A0A8Q3SI75
    10. XM_054325381.1XP_054181356.1  RNA binding protein fox-1 homolog 2 isoform X16

      UniProtKB/TrEMBL
      A0A0G2JRA5
    11. XM_054325377.1XP_054181352.1  RNA binding protein fox-1 homolog 2 isoform X12

      UniProtKB/TrEMBL
      B0QYY4
    12. XM_054325376.1XP_054181351.1  RNA binding protein fox-1 homolog 2 isoform X11

      UniProtKB/TrEMBL
      F8WSN4
    13. XM_054325374.1XP_054181349.1  RNA binding protein fox-1 homolog 2 isoform X9

      UniProtKB/TrEMBL
      F8WSN4
    14. XM_054325375.1XP_054181350.1  RNA binding protein fox-1 homolog 2 isoform X10

      UniProtKB/TrEMBL
      F8WSN4
    15. XM_054325395.1XP_054181370.1  RNA binding protein fox-1 homolog 2 isoform X30

      UniProtKB/TrEMBL
      A0A8Q3SI75
    16. XM_054325383.1XP_054181358.1  RNA binding protein fox-1 homolog 2 isoform X18

      UniProtKB/TrEMBL
      F8WSN4
    17. XM_054325393.1XP_054181368.1  RNA binding protein fox-1 homolog 2 isoform X28

      UniProtKB/TrEMBL
      A8MVJ8, B0QYV1
    18. XM_054325396.1XP_054181371.1  RNA binding protein fox-1 homolog 2 isoform X31

      UniProtKB/TrEMBL
      B0QYY4
    19. XM_054325392.1XP_054181367.1  RNA binding protein fox-1 homolog 2 isoform X27

      UniProtKB/TrEMBL
      A8MVJ8, B0QYV1
    20. XM_054325386.1XP_054181361.1  RNA binding protein fox-1 homolog 2 isoform X21

      UniProtKB/TrEMBL
      B0QYY4
    21. XM_054325385.1XP_054181360.1  RNA binding protein fox-1 homolog 2 isoform X20

      UniProtKB/TrEMBL
      F8WSN4
    22. XM_054325391.1XP_054181366.1  RNA binding protein fox-1 homolog 2 isoform X26

      UniProtKB/Swiss-Prot
      A4F5G8, A8K5Z5, B0QYY8, B0QYY9, O43251, Q0PRL5, Q0VH35, Q5TF71, Q6IC09, Q8TD00, Q8WYB1, Q96DZ6, Q96NL7, Q9UGW4, Q9UH33
    23. XM_054325379.1XP_054181354.1  RNA binding protein fox-1 homolog 2 isoform X14

      UniProtKB/TrEMBL
      F8WSN4
    24. XM_054325378.1XP_054181353.1  RNA binding protein fox-1 homolog 2 isoform X13

      UniProtKB/TrEMBL
      F8WSN4
    25. XM_054325394.1XP_054181369.1  RNA binding protein fox-1 homolog 2 isoform X29

      UniProtKB/TrEMBL
      F8WSN4
    26. XM_054325390.1XP_054181365.1  RNA binding protein fox-1 homolog 2 isoform X25

      UniProtKB/Swiss-Prot
      A4F5G8, A8K5Z5, B0QYY8, B0QYY9, O43251, Q0PRL5, Q0VH35, Q5TF71, Q6IC09, Q8TD00, Q8WYB1, Q96DZ6, Q96NL7, Q9UGW4, Q9UH33
    27. XM_054325388.1XP_054181363.1  RNA binding protein fox-1 homolog 2 isoform X23

      UniProtKB/TrEMBL
      A8MVJ8, B0QYV1
    28. XM_054325389.1XP_054181364.1  RNA binding protein fox-1 homolog 2 isoform X24

      UniProtKB/TrEMBL
      A8MVJ8, B0QYV1
    29. XM_054325382.1XP_054181357.1  RNA binding protein fox-1 homolog 2 isoform X17

      UniProtKB/TrEMBL
      F8WSN4
    30. XM_054325380.1XP_054181355.1  RNA binding protein fox-1 homolog 2 isoform X15

      UniProtKB/TrEMBL
      F8WSN4
    31. XM_054325384.1XP_054181359.1  RNA binding protein fox-1 homolog 2 isoform X19

      UniProtKB/TrEMBL
      A0A0G2JRA5