NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_012889.2 RefSeqGene
- Range
-
4979..19740
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_655
mRNA and Protein(s)
-
NM_001170634.1 → NP_001164105.1 RNA-binding protein FUS isoform 2
See identical proteins and their annotated locations for NP_001164105.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in a shorter isoform (2), compared to isoform 1.
- Source sequence(s)
-
AC009088, AI333366, DC361263
- Consensus CDS
-
CCDS58454.1
- UniProtKB/TrEMBL
-
H3BPE7
- Related
- ENSP00000369594.3, ENST00000380244.8
- Conserved Domains (3) summary
-
- COG0724
Location:263 → 373
- RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
- cd12535
Location:282 → 367
- RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
- pfam00641
Location:421 → 448
- zf-RanBP; Zn-finger in Ran binding protein and others
-
NM_001170937.1 → NP_001164408.1 RNA-binding protein FUS isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (3) that is shorter than isoform 1.
- Source sequence(s)
-
AC009088, AI333366, DA541747, DC361263, U36561
- UniProtKB/TrEMBL
-
H3BPE7
- Conserved Domains (3) summary
-
- COG0724
Location:260 → 370
- RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
- cd12535
Location:279 → 364
- RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
- pfam00641
Location:418 → 445
- zf-RanBP; Zn-finger in Ran binding protein and others
-
NM_004960.4 → NP_004951.1 RNA-binding protein FUS isoform 1
See identical proteins and their annotated locations for NP_004951.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AC009088, BC002459
- Consensus CDS
-
CCDS10707.1
- UniProtKB/Swiss-Prot
-
P35637
- UniProtKB/TrEMBL
- H3BPE7, Q6IBQ5
- Related
- ENSP00000254108.8, ENST00000254108.12
- Conserved Domains (2) summary
-
- cd12535
Location:283 → 368
- RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
- pfam00641
Location:422 → 449
- zf-RanBP; Zn-finger in Ran binding protein and others
RNA
-
NR_028388.2 RNA Sequence
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) omits an exon in the coding sequence, compared to variant 1, resulting in a frameshift and premature stop codon. The transcript is predicted to be subject to nonsense-mediated decay and thus the truncated protein is not annotated.
- Source sequence(s)
-
AC009088, AI333366, AW408771, DC361263
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000016.10 Reference GRCh38.p14 Primary Assembly
- Range
-
31180110..31194871
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_011545781.2 → XP_011544083.1 RNA-binding protein FUS isoform X1
- UniProtKB/TrEMBL
- A0AAQ5BIG2, H3BPE7
- Related
- ENSP00000520462.1, ENST00000715542.1
- Conserved Domains (3) summary
-
- COG0724
Location:262 → 372
- RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
- cd12535
Location:281 → 366
- RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
- pfam00641
Location:420 → 447
- zf-RanBP; Zn-finger in Ran binding protein and others
-
XM_024450221.2 → XP_024305989.1 RNA-binding protein FUS isoform X2
- UniProtKB/TrEMBL
-
H3BPE7
- Conserved Domains (2) summary
-
- cd12535
Location:280 → 365
- RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
- pfam00641
Location:419 → 446
- zf-RanBP; Zn-finger in Ran binding protein and others
-
XM_011545782.3 → XP_011544084.1 RNA-binding protein FUS isoform X3
See identical proteins and their annotated locations for XP_011544084.1
- UniProtKB/TrEMBL
-
Q59H57
- Conserved Domains (3) summary
-
- COG0724
Location:63 → 169
- RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
- cd12535
Location:78 → 163
- RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
- pfam00641
Location:217 → 244
- zf-RanBP; Zn-finger in Ran binding protein and others
Alternate T2T-CHM13v2.0
Genomic
-
NC_060940.1 Alternate T2T-CHM13v2.0
- Range
-
31567541..31582292
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054379990.1 → XP_054235965.1 RNA-binding protein FUS isoform X1
- UniProtKB/TrEMBL
- A0AAQ5BIG2, H3BPE7
-
XM_054379991.1 → XP_054235966.1 RNA-binding protein FUS isoform X2
- UniProtKB/TrEMBL
-
H3BPE7
-
XM_054379992.1 → XP_054235967.1 RNA-binding protein FUS isoform X3
- UniProtKB/TrEMBL
-
Q59H57
The following Reference Sequences have been suppressed. Explain
These RefSeqs were suppressed for the
cited reason(s). Suppressed RefSeqs do not appear in BLAST databases, related
sequence links, or BLAST links (BLink), but may still be retrieved by clicking on
their accession.version below.
-
NM_001010850.1: Suppressed sequence
- Description
- NM_001010850.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.