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    DNM3 dynamin 3 [ Homo sapiens (human) ]

    Gene ID: 26052, updated on 10-Dec-2024

    Summary

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    Official Symbol
    DNM3provided by HGNC
    Official Full Name
    dynamin 3provided by HGNC
    Primary source
    HGNC:HGNC:29125
    See related
    Ensembl:ENSG00000197959 MIM:611445; AllianceGenome:HGNC:29125
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    Dyna III
    Summary
    This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
    Expression
    Biased expression in brain (RPKM 10.0), adrenal (RPKM 2.5) and 8 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See DNM3 in Genome Data Viewer
    Location:
    1q24.3
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (171841498..172418466)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (171198091..171775179)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (171810638..172387606)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr1:171786162-171787148 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr1:171787149-171788134 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1551 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2086 Neighboring gene ribosomal protein S15 pseudogene 3 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr1:171840934-171841454 Neighboring gene ribosomal protein lateral stalk subunit P1 pseudogene 3 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2087 Neighboring gene DNM3 intronic transcript 1 Neighboring gene MPRA-validated peak455 silencer Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:171911601-171912102 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:171935008-171935684 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr1:171935685-171936361 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:171952925-171953114 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:172025253-172025838 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2088 Neighboring gene microRNA 199a-2 Neighboring gene microRNA 3120 Neighboring gene DNM3 opposite strand/antisense RNA Neighboring gene microRNA 214 Neighboring gene MPRA-validated peak456 silencer Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr1:172247487-172248141 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:172300102-172300228 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2089 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2090 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr1:172329514-172330140 Neighboring gene uncharacterized LOC102724528 Neighboring gene RNA, U6 small nuclear 157, pseudogene Neighboring gene NANOG hESC enhancer GRCh37_chr1:172397968-172398490 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:172413041-172413564 Neighboring gene chromosome 1 open reading frame 105 Neighboring gene Sharpr-MPRA regulatory region 10840 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:172466106-172466606 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:172466607-172467107 Neighboring gene Sharpr-MPRA regulatory region 5023 Neighboring gene Sharpr-MPRA regulatory region 3225 Neighboring gene phosphatidylinositol glycan anchor biosynthesis class C Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2092 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2093 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1552 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2094 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:172539927-172540926 Neighboring gene SUN domain containing ossification factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. Two further patients with the 1q24 deletion syndrome expand the phenotype: A possible role for the miR199-214 cluster in the skeletal features of the condition. Ashraf T, et al. Am J Med Genet A, 2015 Dec. PMID 26333682
    2. No association of DNM3 with age of onset in Asian Parkinson's disease. Foo JN, et al. Eur J Neurol, 2019 May. PMID 30133089
    3. No evidence for DNM3 as genetic modifier of age at onset in idiopathic Parkinson's disease. Berge-Seidl V, et al. Neurobiol Aging, 2019 Feb. PMID 30340792, Free PMC Article
    4. Distinct functional effects for dynamin 3 during megakaryocytopoiesis. Wang W, et al. Stem Cells Dev, 2011 Dec. PMID 21671749, Free PMC Article
    5. Distinctive phenotype in 9 patients with deletion of chromosome 1q24-q25. Burkardt DD, et al. Am J Med Genet A, 2011 Jun. PMID 21548129, Free PMC Article

    See all (86) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Integrated multi-omic analysis of low-grade ovarian serous carcinoma collected from short and long-term survivors.
      Title: Integrated multi-omic analysis of low-grade ovarian serous carcinoma collected from short and long-term survivors.
    2. Analysis of DNM3 and VAMP4 as genetic modifiers of LRRK2 Parkinson's disease.
      Title: Analysis of DNM3 and VAMP4 as genetic modifiers of LRRK2 Parkinson's disease.
    3. TBX15 rs98422, DNM3 rs1011731, RAD51B rs8017304, and rs2588809 Gene Polymorphisms and Associations With Pituitary Adenoma.
      Title: TBX15 rs98422, DNM3 rs1011731, RAD51B rs8017304, and rs2588809 Gene Polymorphisms and Associations With Pituitary Adenoma.
    4. The Expression of Dynamin 1, 2, and 3 in Human Hepatocellular Carcinoma and Patient Prognosis.
      Title: The Expression of Dynamin 1, 2, and 3 in Human Hepatocellular Carcinoma and Patient Prognosis.
    5. DNM3 mutation was not associated with age of Parkinson's disease onset in LRRK2 risk variant carriers and non-carriers in Chinese samples
      Title: No association of DNM3 with age of onset in Asian Parkinson's disease.
    6. There is no evidence of an association between DNM3 variants and age at onset in idiopathic Parkinson's disease.
      Title: No evidence for DNM3 as genetic modifier of age at onset in idiopathic Parkinson's disease.
    7. In glioma, elevated miR-221 expression is a biomarker for glioma. DNM3 is a target of miR-221 and RELA regulates miR-221 expression.
      Title: Exosomal miR-221 targets DNM3 to induce tumor progression and temozolomide resistance in glioma.
    8. Genetic variability in DNM3 modifies age of onset for LRRK2 Gly2019Ser parkinsonism.
      Title: DNM3 and genetic modifiers of age of onset in LRRK2 Gly2019Ser parkinsonism: a genome-wide linkage and association study.
    9. DNM3 may be involved in risk of obsessive-compulsive disorder.
      Title: Exon-focused genome-wide association study of obsessive-compulsive disorder and shared polygenic risk with schizophrenia.
    10. Microdeletion of DNM3 harboring miR199 and miR214 is associated with skeletal abnormalities.
      Title: Two further patients with the 1q24 deletion syndrome expand the phenotype: A possible role for the miR199-214 cluster in the skeletal features of the condition.
    Submit: New GeneRIF Correction See all GeneRIFs (21)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    EBI GWAS Catalog

    Description
    A genome- and phenome-wide association study to identify genetic variants influencing platelet count and volume and their pleiotropic effects.
    EBI GWAS Catalog
    A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.
    EBI GWAS Catalog
    Genetic Loci Associated with Circulating Levels of Very Long-Chain Saturated Fatty Acids.
    EBI GWAS Catalog
    Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
    EBI GWAS Catalog
    Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
    EBI GWAS Catalog
    Hundreds of variants clustered in genomic loci and biological pathways affect human height.
    EBI GWAS Catalog
    Many sequence variants affecting diversity of adult human height.
    EBI GWAS Catalog
    Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
    EBI GWAS Catalog
    Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
    EBI GWAS Catalog
    New gene functions in megakaryopoiesis and platelet formation.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    HIV-1 interactions

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    Replication interactions

    Interaction Pubs
    Knockdown of DNM3 by shRNA significantly inhibits HIV-1 replication in CD4+ T-cells PubMed

    Protein interactions

    Protein Gene Interaction Pubs
    Pr55(Gag) gag Dynamin-dependent endocytosis is required for intracellular accumulation of HIV-1 Gag in the presence of HLA-DR PubMed
    gag HIV-1 Gag co-localizes with dynamin in primary T lymphocytes PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA0820, MGC70433

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables membrane scission GTPase motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nitric-oxide synthase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of postsynapse IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables type 1 metabotropic glutamate receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables type 5 metabotropic glutamate receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in endocytosis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in filopodium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in negative regulation of dendritic spine morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of filopodium assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of synaptic vesicle recycling IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in postsynapse organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in receptor internalization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synapse assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in synaptic vesicle budding from presynaptic endocytic zone membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of apical tubulobulbar complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of basal tubulobulbar complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in dendritic spine ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in dendritic spine head IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in extracellular exosome HDA PubMed 
    located_in glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in perinuclear region of cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in postsynaptic density ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in postsynaptic endocytic zone membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in presynapse IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in synaptic cleft IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    dynamin-3
    Names
    T-dynamin
    dynamin family member
    dynamin, testicular
    NP_001129599.1
    NP_001265181.1
    NP_001337133.1
    NP_001337134.1
    NP_001337135.1
    NP_056384.2
    XP_005245136.1
    XP_016856465.1
    XP_016856466.1
    XP_016856467.1
    XP_016856468.1
    XP_016856469.1
    XP_016856471.1
    XP_016856473.1
    XP_016856474.1
    XP_016856475.1
    XP_016856477.1
    XP_016856478.1
    XP_016856480.1
    XP_016856481.1
    XP_047273345.1
    XP_047273351.1
    XP_047273355.1
    XP_047273365.1
    XP_047273373.1
    XP_054191855.1
    XP_054191856.1
    XP_054191857.1
    XP_054191858.1
    XP_054191859.1
    XP_054191860.1
    XP_054191861.1
    XP_054191862.1
    XP_054191863.1
    XP_054191864.1
    XP_054191865.1
    XP_054191866.1
    XP_054191867.1
    XP_054191868.1
    XP_054191869.1
    XP_054191870.1
    XP_054191871.1
    XP_054191872.1
    XP_054191873.1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001136127.3 → NP_001129599.1  dynamin-3 isoform b

      See identical proteins and their annotated locations for NP_001129599.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1. The encoded isoform (b) is shorter than isoform a.
      Source sequence(s)
      AB020627, AL035110, AL136712, BC037326, DC334207, Z97195
      Consensus CDS
      CCDS44276.1
      UniProtKB/Swiss-Prot
      Q9UQ16
      Related
      ENSP00000356705.1, ENST00000367731.5
      Conserved Domains (6) summary
      smart00053
      Location:6 → 245
      DYNc; Dynamin, GTPase
      COG0699
      Location:79 → 728
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      cd01256
      Location:514 → 625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:217 → 502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:647 → 735
      GED; Dynamin GTPase effector domain
      cl22974
      Location:762 → 822
      HpaP; Type III secretion protein (HpaP)

    2. NM_001278252.2 → NP_001265181.1  dynamin-3 isoform c

      See identical proteins and their annotated locations for NP_001265181.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) lacks multiple 3' coding exons and contains an alternate 3' exon, resulting in a distinct 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (c) is shorter and has a distinct C-terminus, compared to isoform a.
      Source sequence(s)
      BC064546, DC334207
      Consensus CDS
      CCDS60356.1
      UniProtKB/TrEMBL
      B3KPF2
      Related
      ENSP00000356707.2, ENST00000367733.6
      Conserved Domains (3) summary
      smart00053
      Location:6 → 245
      DYNc; Dynamin, GTPase
      pfam01031
      Location:216 → 501
      Dynamin_M; Dynamin central region
      cl17171
      Location:514 → 553
      PH-like; Pleckstrin homology-like domain

    3. NM_001350204.2 → NP_001337133.1  dynamin-3 isoform d

      Status: REVIEWED

      Source sequence(s)
      AB020627, AL035110, AL136712, AL512843, BC037326, DC334207, Z97195
      Consensus CDS
      CCDS86032.1
      UniProtKB/Swiss-Prot
      A9Z1Y1, O14982, O95555, Q1MTM8, Q5W129, Q6P2G1, Q9H0P3, Q9H548, Q9NQ68, Q9NQN6, Q9UQ16
      Related
      ENSP00000347457.5, ENST00000355305.9
      Conserved Domains (5) summary
      smart00053
      Location:6 → 245
      DYNc; Dynamin, GTPase
      cd01256
      Location:526 → 635
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216 → 501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:657 → 745
      GED; Dynamin GTPase effector domain
      cl26464
      Location:754 → 841
      Atrophin-1; Atrophin-1 family

    4. NM_001350205.2 → NP_001337134.1  dynamin-3 isoform e

      Status: REVIEWED

      Source sequence(s)
      AL512843, BC064546, DC334207
      UniProtKB/TrEMBL
      B3KPF2
      Conserved Domains (3) summary
      smart00053
      Location:6 → 245
      DYNc; Dynamin, GTPase
      pfam01031
      Location:216 → 501
      Dynamin_M; Dynamin central region
      cl17171
      Location:526 → 563
      PH-like; Pleckstrin homology-like domain

    5. NM_001350206.2 → NP_001337135.1  dynamin-3 isoform f

      Status: REVIEWED

      Source sequence(s)
      AB020627, AL035110, AL512843, CA445187, DC334207
      Consensus CDS
      CCDS91107.1
      UniProtKB/TrEMBL
      H0YBC6
      Related
      ENSP00000429165.2, ENST00000485254.3
      Conserved Domains (5) summary
      smart00053
      Location:6 → 245
      DYNc; Dynamin, GTPase
      cd01256
      Location:526 → 635
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216 → 501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:657 → 745
      GED; Dynamin GTPase effector domain
      cl26464
      Location:754 → 838
      Atrophin-1; Atrophin-1 family

    6. NM_015569.5 → NP_056384.2  dynamin-3 isoform a

      See identical proteins and their annotated locations for NP_056384.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
      Source sequence(s)
      AB020627, AL035110, AL136712, BC037326, DC334207, Z97195
      Consensus CDS
      CCDS53431.1
      UniProtKB/Swiss-Prot
      Q9UQ16
      Related
      ENSP00000486701.1, ENST00000627582.3
      Conserved Domains (6) summary
      smart00053
      Location:6 → 245
      DYNc; Dynamin, GTPase
      COG0699
      Location:79 → 732
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      cd01256
      Location:514 → 625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:217 → 502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:651 → 739
      GED; Dynamin GTPase effector domain
      cl22974
      Location:766 → 826
      HpaP; Type III secretion protein (HpaP)

    RNA

    1. NR_146559.2 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AB020627, AL035110, AL136712, AL512843, BC037326, DC334207, Z97195

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      171841498..172418466
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017000979.2 → XP_016856468.1  dynamin-3 isoform X4

    2. XM_017000984.2 → XP_016856473.1  dynamin-3 isoform X8

    3. XM_047417389.1 → XP_047273345.1  dynamin-3 isoform X10

    4. XM_017000976.2 → XP_016856465.1  dynamin-3 isoform X1

    5. XM_017000977.2 → XP_016856466.1  dynamin-3 isoform X2

    6. XM_005245079.2 → XP_005245136.1  dynamin-3 isoform X6

      UniProtKB/Swiss-Prot
      Q9UQ16
      Conserved Domains (6) summary
      smart00053
      Location:6 → 245
      DYNc; Dynamin, GTPase
      COG0699
      Location:79 → 742
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      cd01256
      Location:526 → 635
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:217 → 502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:661 → 749
      GED; Dynamin GTPase effector domain
      cl22974
      Location:776 → 836
      HpaP; Type III secretion protein (HpaP)

    7. XM_017000982.3 → XP_016856471.1  dynamin-3 isoform X7

    8. XM_017000978.2 → XP_016856467.1  dynamin-3 isoform X3

    9. XM_017000985.2 → XP_016856474.1  dynamin-3 isoform X9

    10. XM_047417399.1 → XP_047273355.1  dynamin-3 isoform X14

      UniProtKB/TrEMBL
      B3KPF2

    11. XM_047417417.1 → XP_047273373.1  dynamin-3 isoform X17

      UniProtKB/TrEMBL
      B3KPF2
      Related
      ENSP00000429701.1, ENST00000520906.5

    12. XM_017000991.2 → XP_016856480.1  dynamin-3 isoform X16

      UniProtKB/TrEMBL
      B3KPF2
      Conserved Domains (3) summary
      smart00053
      Location:6 → 245
      DYNc; Dynamin, GTPase
      COG0699
      Location:79 → 500
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:217 → 502
      Dynamin_M; Dynamin central region

    13. XM_017000989.2 → XP_016856478.1  dynamin-3 isoform X15

      UniProtKB/TrEMBL
      B3KPF2

    14. XM_017000988.2 → XP_016856477.1  dynamin-3 isoform X12

      UniProtKB/TrEMBL
      B3KPF2

    15. XM_047417395.1 → XP_047273351.1  dynamin-3 isoform X13

      UniProtKB/TrEMBL
      B3KPF2

    16. XM_047417409.1 → XP_047273365.1  dynamin-3 isoform X16

      UniProtKB/TrEMBL
      B3KPF2

    17. XM_017000992.2 → XP_016856481.1  dynamin-3 isoform X18

      UniProtKB/TrEMBL
      B3KPF2

    18. XM_017000980.2 → XP_016856469.1  dynamin-3 isoform X5

    19. XM_017000986.2 → XP_016856475.1  dynamin-3 isoform X11

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      171198091..171775179
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054335883.1 → XP_054191858.1  dynamin-3 isoform X4

    2. XM_054335889.1 → XP_054191864.1  dynamin-3 isoform X10

    3. XM_054335887.1 → XP_054191862.1  dynamin-3 isoform X8

    4. XM_054335880.1 → XP_054191855.1  dynamin-3 isoform X1

    5. XM_054335881.1 → XP_054191856.1  dynamin-3 isoform X2

    6. XM_054335885.1 → XP_054191860.1  dynamin-3 isoform X6

    7. XM_054335882.1 → XP_054191857.1  dynamin-3 isoform X3

    8. XM_054335886.1 → XP_054191861.1  dynamin-3 isoform X7

    9. XM_054335888.1 → XP_054191863.1  dynamin-3 isoform X9

    10. XM_054335893.1 → XP_054191868.1  dynamin-3 isoform X14

      UniProtKB/TrEMBL
      B3KPF2

    11. XM_054335897.1 → XP_054191872.1  dynamin-3 isoform X17

      UniProtKB/TrEMBL
      B3KPF2

    12. XM_054335896.1 → XP_054191871.1  dynamin-3 isoform X16

      UniProtKB/TrEMBL
      B3KPF2

    13. XM_054335894.1 → XP_054191869.1  dynamin-3 isoform X15

      UniProtKB/TrEMBL
      B3KPF2

    14. XM_054335891.1 → XP_054191866.1  dynamin-3 isoform X12

      UniProtKB/TrEMBL
      B3KPF2

    15. XM_054335892.1 → XP_054191867.1  dynamin-3 isoform X13

      UniProtKB/TrEMBL
      B3KPF2

    16. XM_054335895.1 → XP_054191870.1  dynamin-3 isoform X16

      UniProtKB/TrEMBL
      B3KPF2

    17. XM_054335898.1 → XP_054191873.1  dynamin-3 isoform X18

      UniProtKB/TrEMBL
      B3KPF2

    18. XM_054335884.1 → XP_054191859.1  dynamin-3 isoform X5

    19. XM_054335890.1 → XP_054191865.1  dynamin-3 isoform X11

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9UQ16.4 GenPept UniProtKB/Swiss-Prot:Q9UQ16

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