U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SPMIP2 sperm microtubule inner protein 2 [ Homo sapiens (human) ]

    Gene ID: 152940, updated on 17-Sep-2024

    Summary

    Official Symbol
    SPMIP2provided by HGNC
    Official Full Name
    sperm microtubule inner protein 2provided by HGNC
    Primary source
    HGNC:HGNC:26342
    See related
    Ensembl:ENSG00000164123 AllianceGenome:HGNC:26342
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C4orf45
    Expression
    Restricted expression toward testis (RPKM 3.4) See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See SPMIP2 in Genome Data Viewer
    Location:
    4q32.1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (158893134..159082885, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (162243906..162433698, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (159814286..159956381, complement)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene hESC enhancers GRCh37_chr4:159643958-159644541 and GRCh37_chr4:159644542-159645126 Neighboring gene electron transfer flavoprotein dehydrogenase Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15773 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:159690086-159690823 Neighboring gene peptidylprolyl isomerase D Neighboring gene Sharpr-MPRA regulatory region 12747 Neighboring gene RNA, U6 small nuclear 128, pseudogene Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:159766516-159767164 Neighboring gene folliculin interacting protein 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:159802306-159803286 Neighboring gene Sharpr-MPRA regulatory region 14183 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:159823055-159823920 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:159823921-159824786 Neighboring gene uncharacterized LOC124900178 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr4:159917411-159918610 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:159927373-159927905 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22087 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22088 Neighboring gene proteasome activator subunit 2 pseudogene 3 Neighboring gene fatty acid binding protein 5 pseudogene 12 Neighboring gene Sharpr-MPRA regulatory region 3178 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22089 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15775 Neighboring gene Sharpr-MPRA regulatory region 13777 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:160023381-160024072 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15777 Neighboring gene Sharpr-MPRA regulatory region 8742 Neighboring gene Rap guanine nucleotide exchange factor 2 Neighboring gene microRNA 3688-1 Neighboring gene microRNA 3688-2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22090 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22091 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:160096538-160097270 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22092 Neighboring gene Sharpr-MPRA regulatory region 9369 Neighboring gene Sharpr-MPRA regulatory region 10828 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr4:160304254-160304828 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr4:160304829-160305402 Neighboring gene MPRA-validated peak5139 silencer Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr4:160322475-160323674 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22093 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15778 Neighboring gene uncharacterized LOC124900924

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ25371

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    protein SPMIP2
    Names
    sperm associated microtubule inner protein 2
    uncharacterized protein C4orf45

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_152543.3NP_689756.2  protein SPMIP2

      See identical proteins and their annotated locations for NP_689756.2

      Status: VALIDATED

      Source sequence(s)
      AC093700, AC109823, BP369394, DB037602
      Consensus CDS
      CCDS47156.1
      UniProtKB/Swiss-Prot
      A8MPU3, C9J0T8, Q96LM5
      Related
      ENSP00000412215.2, ENST00000434826.3
      Conserved Domains (1) summary
      pfam15123
      Location:22133
      DUF4562; Domain of unknown function (DUF4562)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

      Range
      158893134..159082885 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011531671.3XP_011529973.1  protein SPMIP2 isoform X2

      See identical proteins and their annotated locations for XP_011529973.1

      Conserved Domains (1) summary
      pfam15123
      Location:15126
      DUF4562; Domain of unknown function (DUF4562)
    2. XM_011531672.4XP_011529974.1  protein SPMIP2 isoform X2

      See identical proteins and their annotated locations for XP_011529974.1

      Conserved Domains (1) summary
      pfam15123
      Location:15126
      DUF4562; Domain of unknown function (DUF4562)
    3. XM_047449676.1XP_047305632.1  protein SPMIP2 isoform X1

      UniProtKB/Swiss-Prot
      A8MPU3, C9J0T8, Q96LM5
    4. XM_017007809.2XP_016863298.1  protein SPMIP2 isoform X1

      UniProtKB/Swiss-Prot
      A8MPU3, C9J0T8, Q96LM5
      Conserved Domains (1) summary
      pfam15123
      Location:22133
      DUF4562; Domain of unknown function (DUF4562)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060928.1 Alternate T2T-CHM13v2.0

      Range
      162243906..162433698 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054349053.1XP_054205028.1  protein SPMIP2 isoform X2

    2. XM_054349051.1XP_054205026.1  protein SPMIP2 isoform X1

    3. XM_054349054.1XP_054205029.1  protein SPMIP2 isoform X2

    4. XM_054349052.1XP_054205027.1  protein SPMIP2 isoform X1