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    MLXIPL MLX interacting protein like [ Homo sapiens (human) ]

    Gene ID: 51085, updated on 10-Dec-2024

    Summary

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    Official Symbol
    MLXIPLprovided by HGNC
    Official Full Name
    MLX interacting protein likeprovided by HGNC
    Primary source
    HGNC:HGNC:12744
    See related
    Ensembl:ENSG00000009950 MIM:605678; AllianceGenome:HGNC:12744
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MIO; MLX; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14
    Summary
    This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
    Expression
    Biased expression in fat (RPKM 35.0), liver (RPKM 27.7) and 8 other tissues See more
    Orthologs
    mouse all
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    Genomic context

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    See MLXIPL in Genome Data Viewer
    Location:
    7q11.23
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (73593202..73647907, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (74794073..74848925, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (73007532..73038852, complement)

    Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene BAF chromatin remodeling complex subunit BCL7B Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18250 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18251 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18252 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18253 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18254 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26125 Neighboring gene transducin beta like 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73001900-73002400 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73002401-73002901 Neighboring gene Sharpr-MPRA regulatory region 5103 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73017160-73017696 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73021869-73022452 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr7:73049903-73050752 Neighboring gene Sharpr-MPRA regulatory region 8994 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18255 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18256 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18257 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18258 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18259 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr7:73082323-73083318 Neighboring gene VPS37D subunit of ESCRT-I Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26126 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 26127 Neighboring gene DnaJ heat shock protein family (Hsp40) member C30

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

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    Related articles in PubMed

    1. [Transcription factor ChREBP – the coordinator of carbohydrate and lipid metabolism]. Krawczak J, et al. Postepy Biochem, 2020 Mar 31. PMID 33320482
    2. Glucose 6-phosphate, rather than xylulose 5-phosphate, is required for the activation of ChREBP in response to glucose in the liver. Dentin R, et al. J Hepatol, 2012 Jan. PMID 21835137
    3. Integrated expression profiling and genome-wide analysis of ChREBP targets reveals the dual role for ChREBP in glucose-regulated gene expression. Jeong YS, et al. PLoS One, 2011. PMID 21811631, Free PMC Article
    4. ChREBP expression in the liver, adipose tissue and differentiated preadipocytes in human obesity. Hurtado del Pozo C, et al. Biochim Biophys Acta, 2011 Dec. PMID 21840420
    5. High prevalence of an anti-hypertriglyceridemic variant of the MLXIPL gene in Central Asia. Nakayama K, et al. J Hum Genet, 2011 Dec. PMID 21938000

    See all (143) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A genome-first approach to variants in MLXIPL and their association with hepatic steatosis and plasma lipids.
      Title: A genome-first approach to variants in MLXIPL and their association with hepatic steatosis and plasma lipids.
    2. Interaction of genetic variation at ADH1B and MLXIPL with alcohol consumption for elevated serum urate level and gout among people of European ethnicity.
      Title: Interaction of genetic variation at ADH1B and MLXIPL with alcohol consumption for elevated serum urate level and gout among people of European ethnicity.
    3. Knockdown of ChREBP ameliorates retinal microvascular endothelial cell injury and angiogenic responses in diabetic retinopathy.
      Title: Knockdown of ChREBP ameliorates retinal microvascular endothelial cell injury and angiogenic responses in diabetic retinopathy.
    4. ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits.
      Title: ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits.
    5. The role of ChREBP in carbohydrate sensing and NAFLD development.
      Title: The role of ChREBP in carbohydrate sensing and NAFLD development.
    6. New insights into the inter-organ crosstalk mediated by ChREBP.
      Title: New insights into the inter-organ crosstalk mediated by ChREBP.
    7. MLXIPL promotes the migration, invasion, and glycolysis of hepatocellular carcinoma cells by phosphorylation of mTOR.
      Title: MLXIPL promotes the migration, invasion, and glycolysis of hepatocellular carcinoma cells by phosphorylation of mTOR.
    8. HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis.
      Title: HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis.
    9. Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Cholesterol) and Triglyceride Concentrations.
      Title: Sugar-Sweetened Beverage Consumption May Modify Associations Between Genetic Variants in the CHREBP (Carbohydrate Responsive Element Binding Protein) Locus and HDL-C (High-Density Lipoprotein Cholesterol) and Triglyceride Concentrations.
    10. Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP.
      Title: Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP.
    Submit: New GeneRIF Correction See all GeneRIFs (87)

    Phenotypes

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    Find tests for this gene in the NIH Genetic Testing Registry (GTR)

    Review eQTL and phenotype association data in this region using PheGenI

    Associated conditions

    Description Tests
    Williams syndrome
    MedGen: C0175702 OMIM: 194050 GeneReviews: Williams Syndrome
    		Compare labs

    EBI GWAS Catalog

    Description
    Biological, clinical and population relevance of 95 loci for blood lipids.
    EBI GWAS Catalog
    Common variants at 30 loci contribute to polygenic dyslipidemia.
    EBI GWAS Catalog
    Discovery and refinement of loci associated with lipid levels.
    EBI GWAS Catalog
    Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia.
    EBI GWAS Catalog
    Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
    EBI GWAS Catalog
    Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
    EBI GWAS Catalog
    Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.
    EBI GWAS Catalog
    Genome-wide association study identifies multiple loci influencing human serum metabolite levels.
    EBI GWAS Catalog
    Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.
    EBI GWAS Catalog
    Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides.
    EBI GWAS Catalog
    Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
    EBI GWAS Catalog
    Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci.
    EBI GWAS Catalog
    Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
    EBI GWAS Catalog
    Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
    EBI GWAS Catalog
    Newly identified loci that influence lipid concentrations and risk of coronary artery disease.
    EBI GWAS Catalog
    Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans.
    EBI GWAS Catalog

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    contributes_to DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables DNA binding NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables DNA-binding transcription activator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific ISA
    Inferred from Sequence Alignment
    more info
    		  
    enables DNA-binding transcription factor binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables carbohydrate response element binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein heterodimerization activity IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    NOT enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in anatomical structure morphogenesis TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in energy homeostasis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in fatty acid homeostasis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in glucose homeostasis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in glucose mediated signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in lipid biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in negative regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in negative regulation of oxidative phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of peptidyl-serine phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in positive regulation of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of fatty acid biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in positive regulation of glycolytic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of lipid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in positive regulation of transcription from RNA polymerase II promoter by glucose IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of DNA-templated transcription NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in triglyceride homeostasis NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chromatin ISA
    Inferred from Sequence Alignment
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		  
    located_in cytosol TAS
    Traceable Author Statement
    more info
    		  
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		  
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of transcription regulator complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    carbohydrate-responsive element-binding protein
    Names
    Mlx interactor
    WS basic-helix-loop-helix leucine zipper protein
    Williams Beuren syndrome chromosome region 14
    Williams-Beuren syndrome chromosome region 14 protein 1
    Williams-Beuren syndrome chromosome region 14 protein 2
    Williams-Beuren syndrome chromosome region 14 protein 3
    carbohydrate response element binding protein
    class D basic helix-loop-helix protein 14
    williams-Beuren syndrome chromosomal region 14 protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_009307.2 RefSeqGene

      Range
      28385..59705
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_032951.3 → NP_116569.1  carbohydrate-responsive element-binding protein isoform alpha

      See identical proteins and their annotated locations for NP_116569.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (alpha).
      Source sequence(s)
      AF156603, AF245470, BC012925
      Consensus CDS
      CCDS5553.1
      UniProtKB/Swiss-Prot
      C5HU02, C5HU03, C5HU04, Q96E48, Q9BY03, Q9BY04, Q9BY05, Q9BY06, Q9NP71, Q9Y2P3
      UniProtKB/TrEMBL
      C5HU01
      Related
      ENSP00000320886.3, ENST00000313375.8
      Conserved Domains (2) summary
      cd00083
      Location:648 → 708
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      cl21462
      Location:694 → 735
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    2. NM_032952.3 → NP_116570.1  carbohydrate-responsive element-binding protein isoform beta

      See identical proteins and their annotated locations for NP_116570.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1, resulting in a shorter protein (isoform beta).
      Source sequence(s)
      AF156603, AF245471, BC012925
      Consensus CDS
      CCDS47605.1
      UniProtKB/TrEMBL
      C5HU01
      Related
      ENSP00000406296.2, ENST00000429400.6
      Conserved Domains (1) summary
      cd00083
      Location:648 → 680
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

    3. NM_032953.3 → NP_116571.1  carbohydrate-responsive element-binding protein isoform gamma

      See identical proteins and their annotated locations for NP_116571.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice site in the coding region, compared to variant 1, resulting in a shorter protein (isoform gamma).
      Source sequence(s)
      AF156603, AF245472, BC012925
      Consensus CDS
      CCDS47606.1
      UniProtKB/TrEMBL
      C5HU01
      Related
      ENSP00000412330.2, ENST00000414749.6
      Conserved Domains (2) summary
      cd00083
      Location:645 → 706
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      cl21462
      Location:692 → 733
      bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

    4. NM_032954.3 → NP_116572.1  carbohydrate-responsive element-binding protein isoform delta

      See identical proteins and their annotated locations for NP_116572.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) uses an alternate in-frame splice site in the coding region, compared to variant 1, resulting in a shorter protein (isoform delta).
      Source sequence(s)
      AF156603, AF245473, BC012925
      Consensus CDS
      CCDS5554.1
      UniProtKB/TrEMBL
      C5HU01
      Related
      ENSP00000346629.1, ENST00000354613.5
      Conserved Domains (1) summary
      cd00083
      Location:645 → 678
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

    RNA

    1. NR_134541.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (5) lacks an internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AF245474, BC012925, BG772360
      Related
      ENST00000345114.9

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

      Range
      73593202..73647907 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047420437.1 → XP_047276393.1  carbohydrate-responsive element-binding protein isoform X9

    2. XM_047420435.1 → XP_047276391.1  carbohydrate-responsive element-binding protein isoform X7

      UniProtKB/TrEMBL
      C5HU01

    3. XM_047420433.1 → XP_047276389.1  carbohydrate-responsive element-binding protein isoform X5

      UniProtKB/TrEMBL
      C5HU01
      Related
      ENSP00000392636.1, ENST00000434326.5

    4. XM_047420434.1 → XP_047276390.1  carbohydrate-responsive element-binding protein isoform X6

      UniProtKB/TrEMBL
      C5HU01

    5. XM_047420432.1 → XP_047276388.1  carbohydrate-responsive element-binding protein isoform X4

      UniProtKB/TrEMBL
      C5HU01

    6. XM_011516278.2 → XP_011514580.1  carbohydrate-responsive element-binding protein isoform X2

      UniProtKB/TrEMBL
      C5HU01
      Conserved Domains (2) summary
      cd00083
      Location:712 → 772
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam08614
      Location:651 → 792
      ATG16; Autophagy protein 16 (ATG16)

    7. XM_011516279.2 → XP_011514581.1  carbohydrate-responsive element-binding protein isoform X3

      UniProtKB/TrEMBL
      C5HU01
      Conserved Domains (1) summary
      cd00083
      Location:713 → 769
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

    8. XM_011516277.2 → XP_011514579.1  carbohydrate-responsive element-binding protein isoform X1

      UniProtKB/TrEMBL
      C5HU01
      Conserved Domains (2) summary
      cd00083
      Location:713 → 773
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      pfam08614
      Location:652 → 793
      ATG16; Autophagy protein 16 (ATG16)

    9. XM_047420436.1 → XP_047276392.1  carbohydrate-responsive element-binding protein isoform X8

    10. XM_017012263.2 → XP_016867752.1  carbohydrate-responsive element-binding protein isoform X10

    RNA

    1. XR_007060040.1 RNA Sequence

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060931.1 Alternate T2T-CHM13v2.0

      Range
      74794073..74848925 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054358326.1 → XP_054214301.1  carbohydrate-responsive element-binding protein isoform X9

    2. XM_054358324.1 → XP_054214299.1  carbohydrate-responsive element-binding protein isoform X7

      UniProtKB/TrEMBL
      C5HU01

    3. XM_054358322.1 → XP_054214297.1  carbohydrate-responsive element-binding protein isoform X5

      UniProtKB/TrEMBL
      C5HU01

    4. XM_054358323.1 → XP_054214298.1  carbohydrate-responsive element-binding protein isoform X6

      UniProtKB/TrEMBL
      C5HU01

    5. XM_054358321.1 → XP_054214296.1  carbohydrate-responsive element-binding protein isoform X4

      UniProtKB/TrEMBL
      C5HU01

    6. XM_054358319.1 → XP_054214294.1  carbohydrate-responsive element-binding protein isoform X2

      UniProtKB/TrEMBL
      C5HU01

    7. XM_054358320.1 → XP_054214295.1  carbohydrate-responsive element-binding protein isoform X3

      UniProtKB/TrEMBL
      C5HU01

    8. XM_054358318.1 → XP_054214293.1  carbohydrate-responsive element-binding protein isoform X1

      UniProtKB/TrEMBL
      C5HU01

    9. XM_054358325.1 → XP_054214300.1  carbohydrate-responsive element-binding protein isoform X8

    10. XM_054358327.1 → XP_054214302.1  carbohydrate-responsive element-binding protein isoform X10

    RNA

    1. XR_008487623.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_032994.2: Suppressed sequence

      Description
      NM_032994.2: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9NP71.1 GenPept UniProtKB/Swiss-Prot:Q9NP71

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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