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    Pate1 prostate and testis expressed 1 [ Mus musculus (house mouse) ]

    Gene ID: 100312987, updated on 9-Aug-2024

    Summary

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    Official Symbol
    Pate1provided by MGI
    Official Full Name
    prostate and testis expressed 1provided by MGI
    Primary source
    MGI:MGI:4936886
    See related
    Ensembl:ENSMUSG00000091215 AllianceGenome:MGI:4936886
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pate; Gm17252
    Summary
    Enables acetylcholine receptor regulator activity. Involved in regulation of neurotransmitter receptor activity. Orthologous to human PATE1 (prostate and testis expressed 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward genital fat pad adult (RPKM 29.3) See more
    Orthologs
    human all
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    Genomic context

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    See Pate1 in Genome Data Viewer
    Location:
    9 A4; 9 20.39 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (35596182..35598686, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (35685079..35687371, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene prostate and testis expressed 3 Neighboring gene prostate and testis expressed 2 Neighboring gene prostate and testis expressed 10 Neighboring gene STARR-seq mESC enhancer starr_23772 Neighboring gene prostate and testis expressed 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Members of the murine Pate family are predominantly expressed in the epididymis in a segment-specific fashion and regulated by androgens and other testicular factors. Turunen HT, et al. Reprod Biol Endocrinol, 2011 Sep 26. PMID 21942998, Free PMC Article
    2. Nine genes abundantly expressed in the epididymis are not essential for male fecundity in mice. Noda T, et al. Andrology, 2019 Sep. PMID 30927342, Free PMC Article
    3. PATE gene clusters code for multiple, secreted TFP/Ly-6/uPAR proteins that are expressed in reproductive and neuron-rich tissues and possess neuromodulatory activity. Levitin F, et al. J Biol Chem, 2008 Jun 13. PMID 18387948, Free PMC Article
    4. Organization, evolution and functions of the human and mouse Ly6/uPAR family genes. Loughner CL, et al. Hum Genomics, 2016 Apr 21. PMID 27098205, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Characterization of a gene cluster consisting of at least 14 expressed Pate gene members, including Acrv1, Sslp1 and a previously uncharacterized gene which we named Pate-X.
      Title: Members of the murine Pate family are predominantly expressed in the epididymis in a segment-specific fashion and regulated by androgens and other testicular factors.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables acetylcholine receptor regulator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of neurotransmitter receptor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    prostate and testis expressed protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001199953.2 → NP_001186882.1  prostate and testis expressed protein 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC113081
      Consensus CDS
      CCDS57669.1
      UniProtKB/TrEMBL
      E9Q658
      Related
      ENSMUSP00000130484.3, ENSMUST00000170021.3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      35596182..35598686 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001167677.1: Suppressed sequence

      Description
      NM_001167677.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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