Wdr20 WD repeat domain 20 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Wdr20provided by MGI
Official Full Name: WD repeat domain 20provided by MGI
Primary source: MGI:MGI:1916891
See related: Ensembl:ENSMUSG00000037957 AllianceGenome:MGI:1916891
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Wdr20a; 2310040A13Rik
Summary: Predicted to enable deubiquitinase activator activity. Predicted to be located in cytoplasm and nucleus. Orthologous to human WDR20 (WD repeat domain 20). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in testis adult (RPKM 4.4), thymus adult (RPKM 3.0) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 12 F1; 12 60.78 cM

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	12	NC_000078.7 (110701459..110770709)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	12	NC_000078.6 (110735025..110804275)

Chromosome 12 - NC_000078.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH136892 (e-PCR)
- UniSTS:218981

UniSTS:224875 (e-PCR)
- UniSTS:224875

AI549910 (e-PCR)
- UniSTS:164514

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables deubiquitinase activator activity	ISO Inferred from Sequence Orthology more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: WD repeat-containing protein 20

Names: WD repeat domain 20A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001347428.2 → NP_001334357.1 WD repeat-containing protein 20 isoform 2

Status: VALIDATED

Source sequence(s)

AK009711, BP753580

Consensus CDS

CCDS84002.1

UniProtKB/TrEMBL

A0A0A6YX87, Q9D721

Related

ENSMUSP00000141678.2, ENSMUST00000193053.6
NM_001364272.1 → NP_001351201.1 WD repeat-containing protein 20 isoform 3

Status: VALIDATED

Source sequence(s)

AL596265

UniProtKB/TrEMBL

A0A1Y7VJI5

Conserved Domains (2) summary

sd00039
Location:113 → 178

7WD40; WD40 repeat [structural motif]

cl25539
Location:109 → 274

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_001364273.1 → NP_001351202.1 WD repeat-containing protein 20 isoform 4

Status: VALIDATED

Source sequence(s)

AL596265

UniProtKB/TrEMBL

A0A1Y7VJI5

Conserved Domains (2) summary

sd00039
Location:12 → 77

7WD40; WD40 repeat [structural motif]

cl25539
Location:8 → 173

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
NM_027149.4 → NP_081425.2 WD repeat-containing protein 20 isoform 1

See identical proteins and their annotated locations for NP_081425.2

Status: VALIDATED

Source sequence(s)

AI303487, AK136417, BC064773

Consensus CDS

CCDS26173.1

UniProtKB/TrEMBL

Q3ULP2, Q3UWE6

Related

ENSMUSP00000093059.3, ENSMUST00000095410.8

Conserved Domains (3) summary

COG2319
Location:147 → 389

WD40; WD40 repeat [General function prediction only]

sd00039
Location:153 → 218

7WD40; WD40 repeat [structural motif]

cl02567
Location:149 → 314

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000078.7 Reference GRCm39 C57BL/6J

Range

110701459..110770709

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006516203.4 → XP_006516266.1 WD repeat-containing protein 20 isoform X1

UniProtKB/TrEMBL

Q3ULP2

Conserved Domains (2) summary

sd00039
Location:153 → 218

7WD40; WD40 repeat [structural motif]

cl29593
Location:149 → 314

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_006516204.4 → XP_006516267.1 WD repeat-containing protein 20 isoform X2

UniProtKB/TrEMBL

Q3ULP2

Conserved Domains (2) summary

sd00039
Location:153 → 218

7WD40; WD40 repeat [structural motif]

cl29593
Location:149 → 314

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_036157607.1 → XP_036013500.1 WD repeat-containing protein 20 isoform X7

UniProtKB/TrEMBL

A0A0A6YX87
XM_036157606.1 → XP_036013499.1 WD repeat-containing protein 20 isoform X7

UniProtKB/TrEMBL

A0A0A6YX87
XM_006516205.4 → XP_006516268.1 WD repeat-containing protein 20 isoform X3

UniProtKB/TrEMBL

A0A1Y7VJI5

Conserved Domains (2) summary

sd00039
Location:113 → 178

7WD40; WD40 repeat [structural motif]

cl29593
Location:109 → 274

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_036157605.1 → XP_036013498.1 WD repeat-containing protein 20 isoform X4

UniProtKB/TrEMBL

A0A1Y7VJI5

Conserved Domains (2) summary

sd00039
Location:113 → 178

7WD40; WD40 repeat [structural motif]

cl29593
Location:109 → 274

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_030246901.1 → XP_030102761.1 WD repeat-containing protein 20 isoform X6

UniProtKB/TrEMBL

A0A1Y7VJI5

Conserved Domains (2) summary

sd00039
Location:50 → 86

7WD40; WD40 repeat [structural motif]

cl29593
Location:47 → 146

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_011244170.4 → XP_011242472.1 WD repeat-containing protein 20 isoform X5

See identical proteins and their annotated locations for XP_011242472.1

UniProtKB/TrEMBL

A0A1Y7VJI5

Conserved Domains (2) summary

sd00039
Location:12 → 77

7WD40; WD40 repeat [structural motif]

cl29593
Location:8 → 173

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_006516207.5 → XP_006516270.1 WD repeat-containing protein 20 isoform X6

UniProtKB/TrEMBL

A0A1Y7VJI5

Conserved Domains (2) summary

sd00039
Location:50 → 86

7WD40; WD40 repeat [structural motif]

cl29593
Location:47 → 146

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...