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    MX2 MX dynamin like GTPase 2 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 780935, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MX2provided by VGNC
    Official Full Name
    MX dynamin like GTPase 2provided by VGNC
    Primary source
    VGNC:VGNC:81723
    Locus tag
    EGK_13224
    See related
    Ensembl:ENSMMUG00000044257
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human all
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    Genomic context

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    See MX2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (5231296..5275461, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (5263958..5307761, complement)

    Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene transmembrane serine protease 2 Neighboring gene MX dynamin like GTPase 1 Neighboring gene uncharacterized LOC114676800 Neighboring gene FAM3 metabolism regulating signaling molecule B Neighboring gene beta-secretase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in defense response to virus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interferon-induced GTP-binding protein Mx2
    Names
    myxovirus (influenza virus) resistance 2
    myxovirus resistance 2
    myxovirus resistance protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079696.1 → NP_001073164.1  interferon-induced GTP-binding protein Mx2

      See identical proteins and their annotated locations for NP_001073164.1

      Status: PROVISIONAL

      Source sequence(s)
      EF101562
      UniProtKB/Swiss-Prot
      A1E2I5
      UniProtKB/TrEMBL
      A0A5F8A5U2, A0A8J8Y4X6, F7HME1, G7MMR1, H9Z970
      Related
      ENSMMUP00000072281.1, ENSMMUT00000104821.1
      Conserved Domains (3) summary
      smart00302
      Location:621 → 709
      GED; Dynamin GTPase effector domain
      cd08771
      Location:116 → 387
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:308 → 594
      Dynamin_M; Dynamin central region

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041756.1 Reference Mmul_10 Primary Assembly

      Range
      5231296..5275461 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015132841.2 → XP_014988327.1  interferon-induced GTP-binding protein Mx2 isoform X1

      UniProtKB/Swiss-Prot
      A1E2I5
      UniProtKB/TrEMBL
      A0A5F8A5U2, A0A8J8Y4X6, F7HME1, G7MMR1, H9Z970
      Related
      ENSMMUP00000068364.1, ENSMMUT00000105314.1
      Conserved Domains (3) summary
      smart00302
      Location:621 → 709
      GED; Dynamin GTPase effector domain
      cd08771
      Location:116 → 387
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:308 → 594
      Dynamin_M; Dynamin central region

    2. XM_015132843.2 → XP_014988329.1  interferon-induced GTP-binding protein Mx2 isoform X1

      UniProtKB/Swiss-Prot
      A1E2I5
      UniProtKB/TrEMBL
      A0A5F8A5U2, A0A8J8Y4X6, F7HME1, G7MMR1, H9Z970
      Related
      ENSMMUP00000070693.1, ENSMMUT00000100424.1
      Conserved Domains (3) summary
      smart00302
      Location:621 → 709
      GED; Dynamin GTPase effector domain
      cd08771
      Location:116 → 387
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:308 → 594
      Dynamin_M; Dynamin central region

    3. XM_015132842.2 → XP_014988328.1  interferon-induced GTP-binding protein Mx2 isoform X1

      UniProtKB/Swiss-Prot
      A1E2I5
      UniProtKB/TrEMBL
      A0A5F8A5U2, A0A8J8Y4X6, F7HME1, G7MMR1, H9Z970
      Related
      ENSMMUP00000024010.3, ENSMMUT00000025665.4
      Conserved Domains (3) summary
      smart00302
      Location:621 → 709
      GED; Dynamin GTPase effector domain
      cd08771
      Location:116 → 387
      DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
      pfam01031
      Location:308 → 594
      Dynamin_M; Dynamin central region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1E2I5.1 GenPept UniProtKB/Swiss-Prot:A1E2I5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.