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    EDN1 endothelin 1 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 699982, updated on 17-Aug-2024

    Summary

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    Official Symbol
    EDN1provided by VGNC
    Official Full Name
    endothelin 1provided by VGNC
    Primary source
    VGNC:VGNC:104374
    Locus tag
    EGK_14478
    See related
    Ensembl:ENSMMUG00000051532
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See EDN1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (157695586..157704399, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (12523700..12530835)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114677705 Neighboring gene uncharacterized LOC106997800 Neighboring gene HIVEP zinc finger 1 Neighboring gene uncharacterized LOC106997798 Neighboring gene uncharacterized LOC106997799

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables endothelin A receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables endothelin B receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular calcium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of prostaglandin-endoperoxide synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of systemic arterial blood pressure by endothelin IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of vasoconstriction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in vein smooth muscle contraction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    endothelin-1
    Names
    Preproendothelin-1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      157695586..157704399 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015135571.2 → XP_014991057.1  endothelin-1

      UniProtKB/TrEMBL
      A0A5F7ZBR6, A0A8J8XEF4, F7FGG2
      Related
      ENSMMUP00000062615.1, ENSMMUT00000093409.1
      Conserved Domains (2) summary
      smart00272
      Location:108 → 129
      END; Endothelin
      pfam00322
      Location:49 → 77
      Endothelin; Endothelin family
    Nucleotide Protein
    Heading Accession and Version

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